Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Felicity J, Ashcroft"'
Autor:
Merete Haedersdal, Kim Kilov, Vinzent Kevin Ortner, Berit Johansen, Alejandro Castillo Mondragón, Tore Duvold, Jesper Kihl, Felicity J Ashcroft, Astrid J Feuerherm, Charlotte Pind Laugesen, Maiken Lise Marcker Espersen, Ionela Manole, Ari Pall Isberg, Anders Daniel Andersen, Elin Rakvaag, John R Zibert
Publikováno v:
BMJ Open, Vol 12, Iss 10 (2022)
Introduction Actinic keratosis (AK) is the most common precancerous skin condition caused by long-term UV exposure. Given the high recurrence rate of 15%–53%, identifying safe and effective treatment options is warranted. AVX001, a cytosolic phosph
Externí odkaz:
https://doaj.org/article/d5d4e2ebf072461090e79050543e54be
Autor:
Nur Mahammad, Felicity J. Ashcroft, Astrid J. Feuerherm, Samah Elsaadi, Esten N. Vandsemb, Magne Børset, Berit Johansen
Publikováno v:
Molecules, Vol 26, Iss 24, p 7447 (2021)
Cytosolic phospholipase A2α (cPLA2α) is the rate-limiting enzyme in releasing arachidonic acid and biosynthesis of its derivative eicosanoids. Thus, the catalytic activity of cPLA2α plays an important role in cellular metabolism in healthy as well
Externí odkaz:
https://doaj.org/article/f228e61316824e23ad71bf97edf0138e
Autor:
Felicity J. Ashcroft, Nur Mahammad, Helene Midtun Flatekvål, Astrid J. Feuerherm, Berit Johansen
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1402 (2020)
As a regulator of cellular inflammation and proliferation, cytosolic phospholipase A2 α (cPLA2α) is a promising therapeutic target for psoriasis; indeed, the cPLA2α inhibitor AVX001 has shown efficacy against plaque psoriasis in a phase I/IIa clin
Externí odkaz:
https://doaj.org/article/f495d432e2c446da91063555d0f5ffa2
Autor:
Vinzent Kevin, Ortner, Berit, Johansen, Kim, Kilov, Alejandro, Castillo Mondragón, Tore, Duvold, Jesper, Kihl, Felicity J, Ashcroft, Astrid J, Feuerherm, Charlotte, Pind Laugesen, Maiken Lise, Marcker Espersen, Ionela, Manole, Ari Pall, Isberg, Anders Daniel, Andersen, Elin, Rakvaag, John R, Zibert, Merete, Haedersdal
Publikováno v:
BMJ open. 12(10)
Actinic keratosis (AK) is the most common precancerous skin condition caused by long-term UV exposure. Given the high recurrence rate of 15%-53%, identifying safe and effective treatment options is warranted. AVX001, a cytosolic phospholipase AThis s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::446f3f91dfb7c3180d147c0df5cb5747
https://pubmed.ncbi.nlm.nih.gov/36198452
https://pubmed.ncbi.nlm.nih.gov/36198452
Autor:
Felicity J, Ashcroft, Nur, Mahammad, Helene, Midtun Flatekvål, Astrid, Jullumstrø Feuerherm, Berit, Johansen
Publikováno v:
Biomolecules
As a regulator of cellular inflammation and proliferation, cytosolic phospholipase A2 α (cPLA2α) is a promising therapeutic target for psoriasis; indeed, the cPLA2α inhibitor AVX001 has shown efficacy against plaque psoriasis in a phase I/IIa clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60877ba200ef1e6a6a4e74543b7b2639
https://pubmed.ncbi.nlm.nih.gov/33023184
https://pubmed.ncbi.nlm.nih.gov/33023184
