Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Felicity Chung"'
Autor:
Sina Jami, Jennifer R. Deuis, Tabea Klasfauseweh, Xiaoyang Cheng, Sergey Kurdyukov, Felicity Chung, Andrei L. Okorokov, Shengnan Li, Jiangtao Zhang, Ben Cristofori-Armstrong, Mathilde R. Israel, Robert J. Ju, Samuel D. Robinson, Peng Zhao, Lotten Ragnarsson, Åsa Andersson, Poanna Tran, Vanessa Schendel, Kirsten L. McMahon, Hue N. T. Tran, Yanni K.-Y. Chin, Yifei Zhu, Junyu Liu, Theo Crawford, Saipriyaa Purushothamvasan, Abdella M. Habib, David A. Andersson, Lachlan D. Rash, John N. Wood, Jing Zhao, Samantha J. Stehbens, Mehdi Mobli, Andreas Leffler, Daohua Jiang, James J. Cox, Stephen G. Waxman, Sulayman D. Dib-Hajj, G. Gregory Neely, Thomas Durek, Irina Vetter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Voltage-gated sodium (NaV) channels are critical regulators of neuronal excitability and are targeted by many toxins that directly interact with the pore-forming α subunit, typically via extracellular loops of the voltage-sensing domains, o
Externí odkaz:
https://doaj.org/article/ef7fee6301d340c5b67edc494cc4b801
Autor:
Lipin Loo, Matthew A Waller, Cesar L Moreno, Alexander J Cole, Alberto Ospina Stella, Oltin-Tiberiu Pop, Ann-Kristin Jochum, Omar Hasan Ali, Christopher E Denes, Zina Hamoudi, Felicity Chung, Anupriya Aggarwal, Jason K K Low, Karishma Patel, Rezwan Siddiquee, Taeyoung Kang, Suresh Mathivanan, Joel P Mackay, Wolfram Jochum, Lukas Flatz, Daniel Hesselson, Stuart Turville, G Gregory Neely
Publikováno v:
PLoS Biology, Vol 21, Iss 2, p e3001967 (2023)
Although ACE2 is the primary receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, a systematic assessment of host factors that regulate binding to SARS-CoV-2 spike protein has not been described. Here, we use whole-gen
Externí odkaz:
https://doaj.org/article/a8987683bf0d45a6a15d82980b6d7c2c
Autor:
Cesar L. Moreno, Fernanda V. S. Castanheira, Alberto Ospina Stella, Felicity Chung, Anupriya Aggarwal, Alexander J. Cole, Lipin Loo, Alexander Dupuy, Yvonne Kong, Lejla Hagimola, Jemma Fenwick, Paul Coleman, Michelle Willson, Maxwell Bui-Marinos, Daniel Hesselson, Jennifer Gamble, Freda Passam, Stuart Turville, Paul Kubes, G. Gregory Neely
COVID-19 causes a clinical spectrum of acute and chronic illness and host / virus interactions are not completely understood1,2. To identify host factors that can influence SARS-CoV-2 infection, we screened the human genome for genes that, when upreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4a19e378c3caf6ea3a3ae1473226e35
https://doi.org/10.1101/2023.02.13.528235
https://doi.org/10.1101/2023.02.13.528235
Autor:
Lipin Loo, Matthew A. Waller, Cesar L. Moreno, Alexander J. Cole, Alberto Ospina Stella, Oltin-Tiberiu Pop, Ann-Kristin Jochum, Omar Hasan Ali, Christopher E. Denes, Zina Hamoudi, Felicity Chung, Anupriya Aggarwal, Jason K. K. Low, Karishma Patel, Rezwan Siddiquee, Taeyoung Kang, Suresh Mathivanan, Joel P. Mackay, Lukas Flatz, Daniel Hesselson, Stuart Turville, G. Gregory Neely
Although ACE2 is the primary receptor for SARS-CoV-2 infection, a systematic assessment of host factors that regulate binding to SARS-CoV-2 spike protein has not been described. Here we use whole genome CRISPR activation to identify host factors cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c3221a58d1c406b7ac6266771be1716
https://doi.org/10.1101/2021.11.09.467981
https://doi.org/10.1101/2021.11.09.467981
Autor:
Lipin Loo, Matthew Waller, Alexander Cole, Alberto Stella, Cesar Moreno, Christopher Denes, Zina Hamoudi, Felicity Chung, Anupriya Aggarwal, Jason Low, Karishma Patel, Rezwan Siddiquee, Joel Mackay, Stuart Turville, Daniel Hesselson, G. Neely
The coronavirus pandemic has given everyone in society an education on the harms of spread of respiratory illness. Young healthy athletes are far less likely to suffer severe adverse consequences of viral illnesses than the elderly and frail, but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9590dcceb2e458573b94bc1c2872d28c
https://hdl.handle.net/2123/27003
https://hdl.handle.net/2123/27003
Autor:
Jan Parker-Thornburg, Michael J. Tuvim, Roberto Adachi, Usman I. Nazeer, Junaid Farooq, Felicity Chung, Alan R. Burns, Lucia Piccotti, Brenton L. Scott, Joshua M. Brenner, Burton F. Dickey, Walter V. Velasco, Silvia M. Kreda, Anna Sofia Huerta Delgado, Ana M. Jaramillo, Christopher M. Evans, Zoulikha Azzegagh
Airway mucin secretion is necessary for ciliary clearance of inhaled particles and pathogens, but can be detrimental in pathologies such as asthma and cystic fibrosis. Exocytosis in mammals requires a Munc18 scaffolding protein, and airway secretory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7aec728654cb4ac45befed7ead08baa
https://europepmc.org/articles/PMC6483006/
https://europepmc.org/articles/PMC6483006/