Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Felicity C Stark"'
Autor:
Bassel Akache, Felicity C Stark, Yimei Jia, Lise Deschatelets, Renu Dudani, Blair A Harrison, Gerard Agbayani, Dean Williams, Mohammad P Jamshidi, Lakshmi Krishnan, Michael J McCluskie
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208067 (2018)
Archaeosomes are liposomes traditionally comprised of total polar lipids (TPL) or semi-synthetic glycerolipids of ether-linked isoprenoid phytanyl cores with varied glyco- and amino-head groups. As adjuvants, they induce robust, long-lasting humoral
Externí odkaz:
https://doaj.org/article/ae09ce091bc14a5eb92dd687e4c645d6
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32211 (2012)
Central memory CD8(+) T cells expressing the adhesion molecule CD62L (L-selectin) are potent mediators of anti-cancer immunity due to their ability to proliferate extensively upon antigen re-stimulation. The interaction of selectin with its ligands m
Externí odkaz:
https://doaj.org/article/f427622875144b0f856b538c0b822d07
Autor:
Bassel Akache, Andrew J. Read, Renu Dudani, Blair A. Harrison, Dean Williams, Lise Deschatelets, Yimei Jia, Vandana Chandan, Felicity C. Stark, Gerard Agbayani, Shawn R. Makinen, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Wei Zou, Peter D. Kirkland, Michael J. McCluskie
Publikováno v:
Vaccines, Vol 11, Iss 6, p 1043 (2023)
Vaccines play an important role in maintaining human and animal health worldwide. There is continued demand for effective and safe adjuvants capable of enhancing antigen-specific responses to a target pathogen. Rabbit hemorrhagic disease virus (RHDV)
Externí odkaz:
https://doaj.org/article/8033a136f9c84c7da76024c305c13447
Autor:
Gerard Agbayani, Yimei Jia, Bassel Akache, Vandana Chandan, Umar Iqbal, Felicity C. Stark, Lise Deschatelets, Edmond Lam, Usha D. Hemraz, Sophie Régnier, Lakshmi Krishnan, Michael J. McCluskie
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 9, Pp 2183-2195 (2020)
Archaeosomes are liposomes formulated using total polar lipids (TPLs) or semi-synthetic glycolipids derived from archaea. Conventional archaeosomes with entrapped antigen exhibit robust adjuvant activity as demonstrated by increased antigen-specific
Externí odkaz:
https://doaj.org/article/3e7ef0b9480d48b5baae17d096234b45
Autor:
Bassel Akache, Felicity C. Stark, Umar Iqbal, Wangxue Chen, Yimei Jia, Lakshmi Krishnan, Michael J. McCluskie
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 14, Iss 7, Pp 1746-1759 (2018)
Archaeosomes are liposomes comprised of ether lipids derived from various archaea. Unlike conventional ester-linked liposomes, archaeosomes exhibit high pH and thermal stability. As adjuvants, archaeosomes can induce robust, long-lasting humoral and
Externí odkaz:
https://doaj.org/article/63424f4b264f4f388d085f8757db0a94
Induction of a functional CD8+ T-cell response is the important criterion for cancer vaccines, and it is unclear whether acute or chronic live vectors are better suited for cancer antigen delivery. We have evaluated the tumor protective ability of tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ade8150e7333c63399174537fc4bb6
https://doi.org/10.1158/0008-5472.c.6499031.v1
https://doi.org/10.1158/0008-5472.c.6499031.v1
Autor:
Yimei Jia, Bassel Akache, Gerard Agbayani, Vandana Chandan, Renu Dudani, Blair A. Harrison, Lise Deschatelets, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Felicity C. Stark, Lakshmi Krishnan, Michael J. McCluskie
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 205 (2021)
Archaeosomes, composed of sulfated lactosyl archaeol (SLA) glycolipids, have been proven to be an effective vaccine adjuvant in multiple preclinical models of infectious disease or cancer. SLA archaeosomes are a promising adjuvant candidate due to th
Externí odkaz:
https://doaj.org/article/65ffc8ded7204b35b0730b4fdff4a621
Autor:
Bassel Akache, Gerard Agbayani, Felicity C. Stark, Yimei Jia, Renu Dudani, Blair A. Harrison, Lise Deschatelets, Vandana Chandan, Edmond Lam, Usha D. Hemraz, Sophie Régnier, Lakshmi Krishnan, Michael J. McCluskie
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 257 (2021)
Cancer remains a leading cause of morbidity and mortality worldwide. While novel treatments have improved survival outcomes for some patients, new treatment modalities/platforms are needed to combat a wider variety of tumor types. Cancer vaccines har
Externí odkaz:
https://doaj.org/article/3f660cf4148c43c3ae261ca7eac92d92
Autor:
Graham W. Burton, Trevor J. Mogg, Jacek Stupak, Felicity C. Stark, Susan M. Twine, Jianjun Li
Spontaneous oxidation of β-carotene yields a polymer-rich product (OxBC) also containing small amounts of many apocarotenoids. OxBC extends β-carotene’s benefits beyond vitamin A, finding utility in supporting health in livestock, pets, and human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba65bfef10439c078a02dd26c2d02e4e
https://doi.org/10.1101/2022.06.27.497750
https://doi.org/10.1101/2022.06.27.497750
Autor:
Felicity C. Stark, Bassel Akache, Lise Deschatelets, Anh Tran, Matthew Stuible, Yves Durocher, Michael J. McCluskie, Gerard Agbayani, Renu Dudani, Blair A. Harrison, Tyler M. Renner, Shawn R. Makinen, Jegarubee Bavananthasivam, Diana Duque, Martin Gagne, Joseph Zimmermann, C. David Zarley, Terrence R. Cochrane, Martin Handfield
Publikováno v:
Scientific reports. 12(1)
With the persistence of the SARS-CoV-2 pandemic and the emergence of novel variants, the development of novel vaccine formulations with enhanced immunogenicity profiles could help reduce disease burden in the future. Intranasally delivered vaccines o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4481bae025b8a9cae058b040ecdf8df7
https://pubmed.ncbi.nlm.nih.gov/35697917
https://pubmed.ncbi.nlm.nih.gov/35697917