Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Felicitas Altmayr"'
Autor:
Sarah Schulze, Christian Stöß, Miao Lu, Baocai Wang, Melanie Laschinger, Katja Steiger, Felicitas Altmayr, Helmut Friess, Daniel Hartmann, Bernhard Holzmann, Norbert Hüser
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Stimulation of cytosolic nucleic acid sensors of innate immunity by pathogen-derived nucleic acids is important for antimicrobial defence, but stimulation through self-derived nucleic acids may contribute to autoinflammation and cancer. DNA
Externí odkaz:
https://doaj.org/article/e23109e2d28a4177896768238a57e86e
Autor:
Lina M. Staufer, Katja Steiger, Bernhard Holzmann, Felicitas Altmayr, Daniel Hartmann, Leonie S. Jochheim, Ludwig A Kuebelsbeck, Norbert Hüser, Roland M. Schmid, Guido von Figura, Ana Hidalgo-Sastre, Widya Johannes, Monica Ronderos
Publikováno v:
European journal of immunologyReferences. 51(5)
Stringent regulation of the inflammatory response is crucial for normal tissue regeneration. Here, we analyzed the role of Toll-like receptor 3 (TLR3) in pancreatic regeneration after acute pancreatitis (AP). AP was induced by caerulein treatment in
Autor:
Felicitas Altmayr, Miao Lu, Bernhard Holzmann, Melanie Laschinger, Christian Stöß, D. Hartmann, Baocai Wang, Norbert Hüser
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(8)
TLR3 is implicated in anti-viral immune responses, but may also act as a sensor of tissue damage in the absence of infection. Here, we provide evidence for an essential role of TLR3 in liver regeneration after an acute loss of tissue due to partial h
Autor:
Helmut Friess, Melanie Laschinger, Marcus Brugger, Bernhard Holzmann, Yang Wang, Gabriela Holzmann, Felicitas Altmayr, Kazutake Tsujikawa, Daniel Hartmann, B Wang, Katja Steiger, Percy A. Knolle, Miao Lu, Annika Schneider, Norbert Hüser, Christian Stöß, Dirk Wohlleber, S. Schulze
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(6)
The effectiveness of liver regeneration limits surgical therapies of hepatic disorders and determines patient outcome. Here, we investigated the role of the neuropeptide calcitonin gene-related peptide (CGRP) for liver regeneration after acute or chr
Autor:
Heike Weighardt, Bernhard Holzmann, Felicitas Altmayr, Klaus Pfeffer, Klaus-Peter Janssen, Petra Gais, Gabriela Jusek, Daniel Reim, Tanja Rossmann-Bloeck
Publikováno v:
The Journal of Immunology. 188:5833-5837
Although global MyD88 deficiency attenuates lethal inflammation in sepsis, cell-specific functions of MyD88 remain largely unknown. Using mice with selective expression of MyD88 in myeloid cells (Myd88MYEL), we show that, during polymicrobial septic
Autor:
Marit D. Harzenetter, Petra Gais, Alexander Novotny, Carlos A. Molina, Felicitas Altmayr, Bernhard Holzmann
Publikováno v:
The Journal of Immunology. 179:607-615
Communication between the nervous and immune systems involves the release of neuropeptides, such as calcitonin gene-related peptide (CGRP), from sensory nerves during inflammation. CGRP may inhibit the activities of both innate and adaptive immune ce
Autor:
Bernhard Holzmann, Sylvia Schlautkötter, Felicitas Altmayr, Heike Weighardt, Georg F. Weber, Simone Kaiser-Moore
Publikováno v:
Infection and Immunity. 75:1690-1697
Interleukin-22 (IL-22) is a recently discovered proinflammatory cytokine, structurally related to IL-10. Since IL-22 is induced by lipopolysaccharide in vivo, we studied the role of IL-22 in a model of polymicrobial peritonitis. Quantitative real-tim
Autor:
Bernhard Holzmann, Daniel Reim, Alexander Novotny, Helmut Friess, Felicitas Altmayr, Klaus Emmanuel, Volker Assfalg
Publikováno v:
Immunobiology. 217(6)
It has been postulated that an early systemic inflammatory response syndrome (SIRS) and a subsequent compensatory anti-inflammatory response syndrome (CARS) occur sequentially in sepsis. Co-existence of both is referred to as mixed antagonist respons
Autor:
Bernhard Holzmann, Christopher Tiedje, Petra Gais, Matthias Gaestel, Heike Weighardt, Felicitas Altmayr
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(10)
The adapter protein TRIF mediates signal transduction through TLR3 and TLR4, inducing production of type I IFNs and inflammatory cytokines. The present study investigates the mechanisms by which TRIF signaling controls TNF-α biosynthesis. We provide
Publikováno v:
The Journal of biological chemistry. 285(6)
Sensory nerves may dampen inflammatory processes through the release of the neuropeptide calcitonin gene-related peptide (CGRP). CGRP mediates immunosuppressive activities through up-regulation of interleukin-10 or, alternatively, through an interleu