Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Felicitas Horn"'
Autor:
Josefine Wolff, Svenja Seidel, Pia Wuelfing, Michael Patrick Lux, Christine zu Eulenburg, Martin Smollich, Freerk Baumann, Stephan Seitz, Sherko Kuemmel, Marc Thill, Joke Tio, Michael Braun, Hannah Hollaender, Angenla Seitz, Felicitas Horn, Nadia Harbeck, Rachel Wuerstlein
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionThe negative impact of unmanaged psychological distress on quality of life and outcome in breast cancer survivors has been demonstrated. Fortunately, studies indicate that distress can effectively be addressed and even prevented using evi
Externí odkaz:
https://doaj.org/article/cede718f5e5746a88b00f558393e6b1c
Autor:
Esma Elemenler, Arndt Hartmann, Christina Kriener, Oliver Treeck, Felicitas Horn, Olaf Ortmann, Anette Springwald
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 114:207-211
Genetic variations like single nucleotide polymorphisms (SNPs) in genes involved in estrogen biosynthesis, metabolism and signal transduction have been suggested to affect breast cancer susceptibility. In this study we tested the hypothesis that poly
Publikováno v:
Der Pathologe. 29:319-327
The aim of this study was to unravel the role of the transcription factor inhibitor of DNA binding 4 (ID4) in human breast carcinogenesis in more detail, especially the impact of ID4 promoter methylation on disease progression. Demethylating treatmen
Autor:
Nuran Bektas, PD Dr. E. Dahl, M Chorovicer, A. Hartmann, S. Alkaya, Felicitas Horn, Amjad Naami, Juergen Veeck, Ruth Knüchel, Michael Rose, S. von Serenyi, E. Breuer
Publikováno v:
Der Pathologe. 29:338-346
ITIH5 ist ein kurzlich von uns neu charakterisiertes Extrazellularmatrix-Protein, dessen Expression in einer Vielzahl von humanen Tumorentitaten, wie z. B. dem Mammakarzinom, deutlich herabreguliert wird. Ziel der vorliegenden Studie war es, die mole
Publikováno v:
Therapeutische Umschau. 65:231-234
Die Hormontherapie (HT) in Peri- und Postmenopause mit Östrogenen und Gestagenen ist mit einem erhöhten Mammakarzinomrisiko assoziiert. Hormone spielen eine wichtige Rolle im Entstehungsprozess dieser malignen Erkrankung. Für das Risiko, ein Mamma
Autor:
Oliver Treeck, Ingolf Juhasz-Boess, Claus Lattrich, Regina Goerse, Felicitas Horn, Olaf Ortmann
Publikováno v:
Breast Cancer Research and Treatment. 110:507-520
Estrogen receptor beta gene codes for a variety of transcript isoforms resulting from alternative splicing, which are expressed both in mammary gland and in breast cancer cells. We studied the function of two exon-deleted ERbeta isoforms recently ide
Autor:
Helena Houlihan, Georg Pfeiler, Felicitas Horn, Oliver Treeck, Olaf Ortmann, Angelika Vollmer, Bettina Federhofer
Publikováno v:
Molecular and Cellular Endocrinology. 264:50-60
Estrogen receptor (ER) beta gene codes for different transcript variants resulting from alternative splicing. In this study, we report identification of the two novel human exon-skipped ERbeta transcript isoforms ERbetaDelta125 and ERbetaDelta1256 in
Publikováno v:
Gynäkologische Endokrinologie. 3:271-276
Aromatasehemmer (AH) gewinnen insbesondere durch den Nachweis ihrer Wirksamkeit in der adjuvanten endokrinen Therapie des hormonresponsiven Mammakarzinoms zunehmend an Bedeutung. Der vorliegende Beitrag erlautert die Wirkung der Aromatasehemmer der 3
Publikováno v:
Gynecologic Oncology. 96:678-683
Objective Tamoxifen, which is widely used in the treatment of breast cancer, also has a beneficial effect on cisplatin-refractory ovarian cancer. In this study, we investigated the long-term effects of this drug on estrogen-receptor-positive ovarian
Autor:
Bernhard H. F. Weber, Marcus Karlstetter, Katharina Moeller, Thomas Langmann, Harald Neumann, Rebecca Scholz, Felicitas Horn, Alexander Aslanidis, Caroline Nothdurfter, Rainer Rupprecht
Publikováno v:
Journal of Neuroinflammation
Background The translocator protein (18 kDa) (TSPO) is a mitochondrial protein expressed on reactive glial cells and a biomarker for gliosis in the brain. TSPO ligands have been shown to reduce neuroinflammation in several mouse models of neurodegene