Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Felicidad A. Gonzales"'
Autor:
Daniel J. Weisenberger, Mihaela Velicescu, Jonathan C. Cheng, Felicidad A. Gonzales, Gangning Liang, Peter A. Jones
Publikováno v:
Molecular Cancer Research. 2:62-72
Several alternatively spliced variants of DNA methyltransferase (DNMT) 3b have been described. Here, we identified new murine Dnmt3b mRNA isoforms and found that mouse embryonic stem (ES) cells expressed only Dnmt3b transcripts that contained exons 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d19d2f9ae9e2abf6489c6b5f043dc06
https://doi.org/10.1158/1541-7786.62.2.1
https://doi.org/10.1158/1541-7786.62.2.1
Autor:
Peter A. Jones, Miguel A. Preciado-Lopez, Mihaela Velicescu, Felicidad A. Gonzales, Daniel J. Weisenberger, Yvonne C. Tsai, Gangning Liang
Publikováno v:
Gene. 298:91-99
CpG methylation is mediated by the functions of at least three active DNA methyltransferases (DNMTs). While DNMT1 is thought to perform maintenance methylation, the more recently discovered DNMT3a and DNMT3b enzymes are thought to facilitate de novo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b927f61dcd89a57c838996b5d8c4d8a
https://doi.org/10.1016/s0378-1119(02)00976-9
https://doi.org/10.1016/s0378-1119(02)00976-9
Autor:
Yoshitaka Tomigahara, Gangning Liang, Peter W. Laird, En Li, Yvonne C. Tsai, Matilda F. Chan, Felicidad A. Gonzales, Peter A. Jones
Publikováno v:
Molecular and Cellular Biology. 22:480-491
We used mouse embryonic stem (ES) cells with systematic gene knockouts for DNA methyltransferases to delineate the roles of DNA methyltransferase 1 (Dnmt1) and Dnmt3a and -3b in maintaining methylation patterns in the mouse genome. Dnmt1 alone was ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a5aa52744f9abcddf459c2ec79d109
https://doi.org/10.1128/mcb.22.2.480-491.2002
https://doi.org/10.1128/mcb.22.2.480-491.2002
Autor:
Peter A. Jones, Masakazu Tsutsumi, Eva Uzvolgyi, Felicidad A. Gonzales, Martha M. Pao, Gangning Liang
Publikováno v:
Human Molecular Genetics. 10:903-910
The 5' region for the endothelin receptor B (EDNRB) gene is a complex CpG island giving rise to four individual transcripts initiating within the island. Here, for the first time, we analyze the relationship between methylation and gene expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2a100ab324e180ce86c379fd4fb124
https://doi.org/10.1093/hmg/10.9.903
https://doi.org/10.1093/hmg/10.9.903
Autor:
Felicidad A. Gonzales, Peter A. Jones, Peter W. Nichols, TuDung T. Nguyen, Mimi C. Yu, Carvell T. Nguyen
Publikováno v:
The Prostate. 43:233-242
BACKGROUND Downregulation of genes which negatively control cell cycle progression represents a possible mechanism for prostate tumorigenesis. We examined the expression levels of the p16, p15, p14, and retinoblastoma-susceptibility (RB) genes in pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8ba8b4446da2d777758e4b8aab606d6
https://doi.org/10.1002/(sici)1097-0045(20000515)43:3<233::aid-pros10>3.0.co
https://doi.org/10.1002/(sici)1097-0045(20000515)43:3<233::aid-pros10>3.0.co
Autor:
Khandan Keyomarsi, Felicidad A. Gonzales, Peter A. Jones, Mihaela Velicescu, Keith D. Robertson
Publikováno v:
Nucleic Acids Research. 28:2108-2113
DNA methylation is essential for mammalian development, X-chromosome inactivation, and imprinting yet aberrant methylation patterns are one of the most common features of transformed cells. One of the proposed causes for these defects in the methylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb1240f3fe379789310a03d3397c501
https://doi.org/10.1093/nar/28.10.2108
https://doi.org/10.1093/nar/28.10.2108
Autor:
Carol E. Salem, Peter A. Jones, Felicidad A. Gonzales, Christina M. Bender, Gangning Liang, Isabel D.C. Markl
Publikováno v:
International Journal of Cancer. 87:179-185
The mechanisms underlying the de novo methylation of CpG islands in human cancer remain almost completely unknown. We used a methylation-sensitive arbitrarily primed polymerase chain reaction (Ms AP-PCR) technique to scan genomic DNA for differential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7744e2a1f99e8d353e9e676ef482353
https://doi.org/10.1002/1097-0215(20000715)87:2<179::aid-ijc4>3.0.co
https://doi.org/10.1002/1097-0215(20000715)87:2<179::aid-ijc4>3.0.co
Autor:
Peter A. Jones, Christina M. Bender, Felicidad A. Gonzales, Carvell T. Nguyen, Mark L. Gonzalgo, Keith D. Robertson
Publikováno v:
Molecular and Cellular Biology. 19:6690-6698
De novo methylation of CpG islands within the promoters of eukaryotic genes is often associated with their transcriptional repression, yet the methylation of CpG islands located downstream of promoters does not block transcription. We investigated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4486f0bb5880f09de6dc6f2e42e4eb19
https://doi.org/10.1128/mcb.19.10.6690
https://doi.org/10.1128/mcb.19.10.6690
Autor:
Peter A. Jones, Keith D. Robertson, Janos Sumegi, Cathy Talmadge, Gangning Liang, Eva Uzvolgyi, Felicidad A. Gonzales
Publikováno v:
Nucleic Acids Research. 27:2291-2298
DNA methylation in mammals is required for embryonic development, X chromosome inactivation and imprinting. Previous studies have shown that methylation patterns become abnormal in malignant cells and may contribute to tumorigenesis by improper de no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d87b027500a1d8c97126d147f777d7c
https://doi.org/10.1093/nar/27.11.2291
https://doi.org/10.1093/nar/27.11.2291
Autor:
B M Cattanach, H Sasaki, K D Brown, Anne C. Ferguson-Smith, Peter A. Jones, Felicidad A. Gonzales, M A Surani, P Eversole-Cire
Publikováno v:
Molecular and Cellular Biology. 13:4928-4938
The mouse insulin-like growth factor II gene (Igf 2), located on distal chromosome 7, is parentally imprinted such that the paternal allele is expressed while the maternal allele is transcriptionally silent. We derived a cell line from a mouse embryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8576a1eec0ef55aa4a833e62102ddfef
https://doi.org/10.1128/mcb.13.8.4928
https://doi.org/10.1128/mcb.13.8.4928