Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Felicia Roscoe"'
Autor:
Ren-Huan Xu, Daniel Rubio, Felicia Roscoe, Tracy E Krouse, Mary Ellen Truckenmiller, Christopher C Norbury, Paul N Hudson, Inger K Damon, Antonio Alcamí, Luis J Sigal
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002475 (2012)
Type 1 interferons (T1-IFNs) play a major role in antiviral defense, but when or how they protect during infections that spread through the lympho-hematogenous route is not known. Orthopoxviruses, including those that produce smallpox and mousepox, s
Externí odkaz:
https://doaj.org/article/9654e97fb13447d9ae94d808334ea8ce
Publikováno v:
PLoS Pathogens, Vol 6, Iss 2, p e1000768 (2010)
The extent to which direct- and cross-presentation (DP and CP) contribute to the priming of CD8(+) T cell (T(CD8+)) responses to viruses is unclear mainly because of the difficulty in separating the two processes. Hence, while CP in the absence of DP
Externí odkaz:
https://doaj.org/article/c5dd7851d53441b08aa09d7b1ceaaec1
Publikováno v:
The Journal of Experimental Medicine
Age-related defects in natural killer cell numbers and function underlie the decreased resistance to mousepox infection in aging mice.
Although it is well known that aged hosts are generally more susceptible to viral diseases than the young, spe
Although it is well known that aged hosts are generally more susceptible to viral diseases than the young, spe
Autor:
Eric B. Wong, Savita Nair, Reto A. Schwendener, Ren-Huan Xu, Luis J. Sigal, Shinu John, Xueying Ma, Sanda Remakus, Daniel Rubio, Mark J. Shlomchik, Felicia Roscoe
Publikováno v:
Immunity. 43(6)
SummaryToll-like receptor 9 (TLR9), its adaptor MyD88, the downstream transcription factor interferon regulatory factor 7 (IRF7), and type I interferons (IFN-I) are all required for resistance to infection with ectromelia virus (ECTV). However, it is
Publikováno v:
Journal of virology. 89(1)
It has been shown in various infection models that CD4 + T cell help (T H ) is necessary for the conditioning, maintenance, and/or recall responses of memory CD8 + T cells (CD8 M) . Yet, in the case of vaccinia virus (VACV), which constitutes the vac
Autor:
Luis J. Sigal, Nicholas A. Siciliano, Janet J. Sei, Ren-Huan Xu, Laurence C. Eisenlohr, Christopher C. Norbury, Michael L. Davies, Felicia Roscoe
Publikováno v:
Journal of virology. 88(6)
Although the pattern recognition receptor Toll-like receptor 2 (TLR2) is typically thought to recognize bacterial components, it has been described to alter the induction of both innate and adaptive immunity to a number of viruses, including vaccinia
Autor:
Luis J. Sigal, J. Charles Whitbeck, Felicia Roscoe, Gary H. Cohen, Xueying Ma, Roselyn J. Eisenberg, Ren-Huan Xu
Publikováno v:
Journal of virology. 87(12)
Orthopoxviruses (OPVs), which include the agent of smallpox (variola virus), the zoonotic monkeypox virus, the vaccine and zoonotic species vaccinia virus, and the mouse pathogen ectromelia virus (ECTV), form two types of infectious viral particles:
Publikováno v:
Journal of virology. 86(24)
The orthopoxvirus (OPV) vaccinia virus (VACV) requires an intact F13L gene to produce enveloped virions (EV) and to form plaques in cell monolayers. Simultaneous introduction of an exogenous gene and F13L into F13L -deficient VACV results in expressi
Autor:
Angela Hu, Xueying Ma, Felicia Roscoe, Ahamed R. Shamsedeen, Nicholas A. Siciliano, Luis J. Sigal, Laurence C. Eisenlohr, Adam R. Hersperger, Min Fang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(25)
CD4 + T cells are generally regarded as helpers and regulators of the immune response. Although cytolytic CD4 + T cells have been described, whether those generated during the course of a viral infection play a role in virus control remains unknown.
Autor:
Christopher C. Norbury, Ren-Huan Xu, Paul Hudson, Antonio Alcami, Daniel Rubio, Inger K. Damon, Felicia Roscoe, M.E. Truckenmiller, Luis J. Sigal, Tracy E. Krouse
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002475 (2012)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Pathogens
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Pathogens
Type 1 interferons (T1-IFNs) play a major role in antiviral defense, but when or how they protect during infections that spread through the lympho-hematogenous route is not known. Orthopoxviruses, including those that produce smallpox and mousepox, s