Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Felicia M. Truckenmüller"'
Autor:
Melanie Märklin, Jonas S. Heitmann, Alexander R. Fuchs, Felicia M. Truckenmüller, Michael Gutknecht, Stefanie Bugl, Sebastian J. Saur, Juliane Lazarus, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Hans-Georg Rammensee, Helmut R. Salih, Hans-Georg Kopp, Michael Haap, Andreas Kirschniak, Lothar Kanz, Anjana Rao, Stefan Wirths, Martin R. Müller
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
NFAT2 is a transcription factor that has been linked with chronic lymphocytic leukaemia (CLL), but its functions in CLL manifestation are still unclear. Here the authors show, by analysing mouse CLL models and characterising biopsies from CLL patient
Externí odkaz:
https://doaj.org/article/3d01d0e5fd30417aa6c380e7daff8c86
Autor:
Andreas Kirschniak, Anjana Rao, Michael Gutknecht, Felicia M. Truckenmüller, Hans-Georg Kopp, Jonas S. Heitmann, Stefanie Bugl, Ursula Kohlhofer, Alexander R. Fuchs, Juliane Lazarus, Lothar Kanz, Michael Haap, Stefan Wirths, Melanie Märklin, Sebastian Jonas Saur, Leticia Quintanilla-Martinez, Martin Müller, Hans-Georg Rammensee, Helmut R. Salih
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
Chronic lymphocytic leukaemia (CLL) is a clonal disorder of mature B cells. Most patients are characterised by an indolent disease course and an anergic phenotype of their leukaemia cells, which refers to a state of unresponsiveness to B cell recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7a643886c462e4a36ed56ba43cec3c
http://link.springer.com/article/10.1038/s41467-017-00830-y
http://link.springer.com/article/10.1038/s41467-017-00830-y
Publikováno v:
Journal of neurochemistry 131(6), 848-858 (2014). doi:10.1111/jnc.12813
Parkinson's disease (PD) and diabetes belong to the most common neurodegenerative and metabolic syndromes, respectively. Epidemiological links between these two frequent disorders are controversial. The neuropathological hallmarks of PD are protein a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3677aa3b0ed27af083b59e9a81448b65
https://pub.dzne.de/record/137677
https://pub.dzne.de/record/137677
Autor:
Lothar Kanz, Jonas S. Heitmann, Anjana Rao, Felicia M. Truckenmüller, Alexander R. Fuchs, Posdorowkin Anastasia, Hans-Georg Kopp, Stefan Wirths, Melanie Märklin, Martin R Mueller
Publikováno v:
Blood. 128:4371-4371
NFAT2 is a highly phosphorylated transcription factor which regulates developmental and activation programs in diverse cell types. We and others have previously described a significant overexpression of NFAT2 in CLL cells as compared to physiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1890c9e77560158424ae8cad0703d8b
https://doi.org/10.1182/blood.v128.22.4371.4371
https://doi.org/10.1182/blood.v128.22.4371.4371
Autor:
Manuela Ganser, Bugl Stefanie, Stefan Wirths, Michael Haap, Martin R Mueller, Jonas S. Heitmann, Hans-Georg Kopp, Melanie Märklin, Lothar Kanz, Anjana Rao, Felicia M. Truckenmüller, Sebastian Jonas Saur
Publikováno v:
Blood. 126:364-364
NFAT is a family of highly phosphorylated proteins residing in the cytoplasm of resting cells. Upon dephosphorylation by calcineurin, NFAT proteins translocate to the nucleus where they orchestrate developmental and activation programs in diverse cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e53a6e84f2618c65b0344786d7acf07
https://doi.org/10.1182/blood.v126.23.364.364
https://doi.org/10.1182/blood.v126.23.364.364