Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Felicia Alina Patrascu"'
Autor:
Jean-Stéphane Gatot, Jacques Piette, Rudi Beyaert, Jean-Paul Chapelle, Alain Chariot, Romain Gioia, Felicia Alina Patrascu, Luke A. J. O'Neill, Tieu-Lan Chau, Isabelle Carpentier
Publikováno v:
Trends in Biochemical Sciences. 33:171-180
The IkappaB kinases (IKKs) IKK-alpha and IKK-beta, and the IKK-related kinases TBK1 and IKK-epsilon, have essential roles in innate immunity through signal-induced activation of NF-kappaB, IRF3 and IRF7, respectively. Although the signaling events wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6644a85658e3d258bee13f932efcdf8
https://doi.org/10.1016/j.tibs.2008.01.002
https://doi.org/10.1016/j.tibs.2008.01.002
Autor:
Eric Muraille, Pierre Close, Jean-Paul Chapelle, Alain Chariot, Jacques Piette, Keith Brown, Emmanuel Dejardin, Felicia Alina Patrascu, Tieu-Lan Chau, Romain Gioia, Jean-Stéphane Gatot, Michael Warnier, Ulrich Siebenlist
Publikováno v:
Journal of Biological Chemistry. 282:31131-31146
Type I interferon gene induction relies on IKK-related kinase TBK1 and IKKepsilon-mediated phosphorylations of IRF3/7 through the Toll-like receptor-dependent signaling pathways. The scaffold proteins that assemble these kinase complexes are poorly c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4919bdd23db6028103385f9e9e3bb08
https://doi.org/10.1074/jbc.m701690200
https://doi.org/10.1074/jbc.m701690200
Autor:
Felicia Alina Patrascu, Ayman Rammal, Laurence Borgs, Kateryna Shostak, Alain Chariot, Heike Brinkhaus, Laurent Nguyen, Fabrice Olivier, Pierre Close, Mohamed Bentires-Alj, Jean-Christophe Marine, Serkan Ismail Göktuna
Publikováno v:
Cell death and differentiation. 21(5)
Restoration of p53 tumor suppressor function through inhibition of its interaction and/or enzymatic activity of its E3 ligase, MDM2, is a promising therapeutic approach to treat cancer. However, because the MDM2 targetome extends beyond p53, MDM2 inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9070319f85d17610624f8e62e3faf8
https://pubmed.ncbi.nlm.nih.gov/24488098
https://pubmed.ncbi.nlm.nih.gov/24488098