Zobrazeno 1 - 10
of 2 597
pro vyhledávání: '"Felice C"'
Autor:
Rebika Shrestha, Timothy S. Carpenter, Que N. Van, Constance Agamasu, Marco Tonelli, Fikret Aydin, De Chen, Gulcin Gulten, James N. Glosli, Cesar A. López, Tomas Oppelstrup, Chris Neale, Sandrasegaram Gnanakaran, William K. Gillette, Helgi I. Ingólfsson, Felice C. Lightstone, Andrew G. Stephen, Frederick H. Streitz, Dwight V. Nissley, Thomas J. Turbyville
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract The oncogene RAS, extensively studied for decades, presents persistent gaps in understanding, hindering the development of effective therapeutic strategies due to a lack of precise details on how RAS initiates MAPK signaling with RAF effecto
Externí odkaz:
https://doaj.org/article/c9c372b885d34294a1a4b151fe83ce95
Autor:
Rebika Shrestha, Timothy S. Carpenter, Que N. Van, Constance Agamasu, Marco Tonelli, Fikret Aydin, De Chen, Gulcin Gulten, James N. Glosli, Cesar A. López, Tomas Oppelstrup, Chris Neale, Sandrasegaram Gnanakaran, William K. Gillette, Helgi I. Ingólfsson, Felice C. Lightstone, Andrew G. Stephen, Frederick H. Streitz, Dwight V. Nissley, Thomas J. Turbyville
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/ebd31f95883b42a68c6081c546cb6fe3
Autor:
Leanne M. Mansfield, Sivia K. Lapidus, Samira Nazzar Romero, Lakshmi N. Moorthy, Felice C. Adler-Shohet, Matthew Hollander, Julie Cherian, Marinka Twilt, Geraldina Lionetti, Smriti Mohan, Patricia A. DeLaMora, Karen L. Durrant, Theresa Wampler Muskardin, Mariana Correia Marques, Karen B. Onel, Fatma Dedeoglu, Maria J. Gutierrez, Grant Schulert, the CARRA Autoinflammatory Network Consortium for the CARRA PFAPA/Autoinflammatory Working Group
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/8c2beb3253504e69afcf3364e66e6250
Autor:
Leanne M. Mansfield, Sivia K. Lapidus, Samira Nazzar Romero, Lakshmi N. Moorthy, Felice C. Adler-Shohet, Matthew Hollander, Julie Cherian, Marinka Twilt, Geraldina Lionetti, Smriti Mohan, Patricia A. DeLaMora, Karen L. Durrant, Theresa Wampler Muskardin, Mariana Correia Marques, Karen B. Onel, Fatma Dedeoglu, Maria J. Gutierrez, Grant Schulert, the CARRA Autoinflammatory Network Consortium for the CARRA PFAPA/Autoinflammatory Working Group, Shoghik Akoghlanian, Cassyanne L. Aguiar, Matthew Basiaga, Joyce Hui-Yuen, Elizabeth A. Kessler, Jamie Lai, Brian E. Nolan, Sheila Nolan, Melissa S. Oliver, Heather O Tory, Sirada Panupattanapong, Maryam Piram, Ann Szymanski, Tiphanie Vogel, Eveline Wu
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
The impact of the COVID-19 pandemic on new diagnoses of recurrent fevers and autoinflammatory diseases is largely unknown. The Childhood Arthritis and Rheumatology Research Alliance (CARRA) PFAPA/AID Working Group aimed to investigate the impact of t
Externí odkaz:
https://doaj.org/article/d9253a5419394c93882710b598d05dc8
Autor:
Ya Ju Fan, Jonathan E. Allen, Kevin S. McLoughlin, Da Shi, Brian J. Bennion, Xiaohua Zhang, Felice C. Lightstone
Publikováno v:
Artificial Intelligence Chemistry, Vol 1, Iss 1, Pp 100004- (2023)
Neural Network (NN) models provide potential to speed up the drug discovery process and reduce its failure rates. The success of NN models requires uncertainty quantification (UQ) as drug discovery explores chemical space beyond the training data dis
Externí odkaz:
https://doaj.org/article/efcc644112614a30945cbc2b09c71d37
Autor:
Brian J. Bennion, Michael A. Malfatti, Nicholas A. Be, Heather A. Enright, Saphon Hok, C. Linn Cadieux, Timothy S. Carpenter, Victoria Lao, Edward A. Kuhn, M. Windy McNerney, Felice C. Lightstone, Tuan H. Nguyen, Carlos A. Valdez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Nerve agents have experienced a resurgence in recent times with their use against civilian targets during the attacks in Syria (2012), the poisoning of Sergei and Yulia Skripal in the United Kingdom (2018) and Alexei Navalny in Russia (2020)
Externí odkaz:
https://doaj.org/article/f1620f48e97e419eb3cf95836925d7b8
Autor:
Edmond Y. Lau, Oscar A. Negrete, W. F. Drew Bennett, Brian J. Bennion, Monica Borucki, Feliza Bourguet, Aidan Epstein, Magdalena Franco, Brooke Harmon, Stewart He, Derek Jones, Hyojin Kim, Daniel Kirshner, Victoria Lao, Jacky Lo, Kevin McLoughlin, Richard Mosesso, Deepa K. Murugesh, Edwin A. Saada, Brent Segelke, Maxwell A. Stefan, Garrett A. Stevenson, Marisa W. Torres, Dina R. Weilhammer, Sergio Wong, Yue Yang, Adam Zemla, Xiaohua Zhang, Fangqiang Zhu, Jonathan E. Allen, Felice C. Lightstone
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
A rapid response is necessary to contain emergent biological outbreaks before they can become pandemics. The novel coronavirus (SARS-CoV-2) that causes COVID-19 was first reported in December of 2019 in Wuhan, China and reached most corners of the gl
Externí odkaz:
https://doaj.org/article/d413250ed30f441981cd5475fb7487b8
Autor:
Debanjan Goswami, De Chen, Yue Yang, Prabhakar R Gudla, John Columbus, Karen Worthy, Megan Rigby, Madeline Wheeler, Suman Mukhopadhyay, Katie Powell, William Burgan, Vanessa Wall, Dominic Esposito, Dhirendra K Simanshu, Felice C Lightstone, Dwight V Nissley, Frank McCormick, Thomas Turbyville
Publikováno v:
eLife, Vol 9 (2020)
The RAS proteins are GTP-dependent switches that regulate signaling pathways and are frequently mutated in cancer. RAS proteins concentrate in the plasma membrane via lipid-tethers and hypervariable region side-chain interactions in distinct nano-dom
Externí odkaz:
https://doaj.org/article/c798200b000d4c1ab8ba16fab0ce9c68
