Tissue-resident memory T cells in epicardial adipose tissue comprise transcriptionally distinct subsets that are modulated in atrial fibrillation.

Autor: Vyas V; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Cardiology, Barts Heart Centre, St. Bartholomew's Hospital, London, UK., Sandhar B; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Keane JM; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Wood EG; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Blythe H; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Jones A; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Shahaj E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Fanti S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Williams J; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Metic N; Cancer Research UK, Barts Centre, Queen Mary University of London, London, UK., Efremova M; Cancer Research UK, Barts Centre, Queen Mary University of London, London, UK., Ng HL; Department of Immunology and Inflammation, Centre for Haematology, Faculty of Medicine, Imperial College London, London, UK., Nageswaran G; UCL Division of Infection and Immunity, University College London, London, UK., Byrne S; UCL Division of Infection and Immunity, University College London, London, UK., Feldhahn N; Department of Immunology and Inflammation, Centre for Haematology, Faculty of Medicine, Imperial College London, London, UK., Marelli-Berg F; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Chain B; UCL Division of Infection and Immunity, University College London, London, UK., Tinker A; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Finlay MC; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Cardiology, Barts Heart Centre, St. Bartholomew's Hospital, London, UK., Longhi MP; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. m.longhi@qmul.ac.uk.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2024 Sep; Vol. 3 (9), pp. 1067-1082. Date of Electronic Publication: 2024 Aug 23.

MAF functions as a pioneer transcription factor that initiates and sustains myelomagenesis.

Autor: Katsarou A; Department of Immunology and Inflammation, Hugh & Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Imperial College London, London, United Kingdom.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare National Health Service Trust, London, United Kingdom., Trasanidis N; Department of Immunology and Inflammation, Hugh & Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Imperial College London, London, United Kingdom., Ponnusamy K; Department of Immunology and Inflammation, Hugh & Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Imperial College London, London, United Kingdom., Kostopoulos IV; Department of Immunology and Inflammation, Hugh & Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Imperial College London, London, United Kingdom.; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Alvarez-Benayas J; Department of the Higher School of Computer Science, Nebrija ARIES Research Group, Universidad Antonio de Nebrija, Madrid, Spain., Papaleonidopoulou F; Department of Immunology and Inflammation, Hugh & Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Imperial College London, London, United Kingdom., Keren K; Department of Immunology and Inflammation, Hugh & Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Imperial College London, London, United Kingdom., Sabbattini PMR; Department of Immunology and Inflammation, Hugh & Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Imperial College London, London, United Kingdom., Feldhahn N; Centre for Haematology, Imperial College London, London, United Kingdom., Papaioannou M; Division of Haematology, First Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Hatjiharissi E; Division of Haematology, First Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Sudbery IM; School of Biosciences, University of Sheffield, Sheffield, United Kingdom., Chaidos A; Department of Immunology and Inflammation, Hugh & Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Imperial College London, London, United Kingdom.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare National Health Service Trust, London, United Kingdom., Caputo VS; Department of Immunology and Inflammation, Hugh & Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Imperial College London, London, United Kingdom.; Cancer Biology and Therapy laboratory, School of Applied Science, London South Bank University, London, United Kingdom., Karadimitris A; Department of Immunology and Inflammation, Hugh & Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Imperial College London, London, United Kingdom.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare National Health Service Trust, London, United Kingdom.

Publikováno v: Blood advances [Blood Adv] 2023 Nov 14; Vol. 7 (21), pp. 6395-6410.

Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies.

Autor: Cosgun KN, Jumaa H, Robinson ME, Kistner KM, Xu L, Xiao G, Chan LN, Lee J, Kume K, Leveille E, Fonseca-Arce D, Khanduja D, Ng HL, Feldhahn N, Song J, Chan WC, Chen J, Taketo MM, Kothari S, Davids MS, Schjerven H, Jellusova J, Müschen M

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 15. Date of Electronic Publication: 2023 Mar 15.

The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells.

Autor: Sprangers, M.¹, Feldhahn, N.¹, Herzog, S.², Hansmann, M.-L.³, Reppel, M.⁴, Hescheler, J.⁴, Jumaa, H.², Siebert, R.⁵, Müschen, M.¹ markus.mueschen@uni-duesseldorf.de

Publikováno v: Oncogene. 8/17/2006, Vol. 25 Issue 36, p5056-5062. 7p. 3 Graphs.

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