Four-gene pan-African blood signature predicts progression to tuberculosis

Autor: Sara Suliman, Ethan G. Thompson, Jayne Sutherland, January Weiner, Martin O. C. Ota, Smitha Shankar, Adam Penn-Nicholson, Bonnie Thiel, Mzwandile Erasmus, Jeroen Maertzdorf, Fergal J. Duffy, Philip C. Hill, E. Jane Hughes, Kim Stanley, Katrina Downing, Michelle L. Fisher, Joe Valvo, Shreemanta K. Parida, Gian van der Spuy, Gerard Tromp, Ifedayo M. O. Adetifa, Simon Donkor, Rawleigh Howe, Harriet Mayanja-Kizza, W. Henry Boom, Hazel M. Dockrell, Tom H. M. Ottenhoff, Mark Hatherill, Alan Aderem, Willem A. Hanekom, Thomas J. Scriba, Stefan H. E. Kaufmann, Daniel E. Zak, Gerhard Walzl, Gillian F. Black, Magdalena Kriel, Nelita Du Plessis, Nonhlanhla Nene, Teri Roberts, Leanie Kleynhans, Andrea Gutschmidt, Bronwyn Smith, Andre G. Loxton, Novel N. Chegou, Gerhardus Tromp, David Tabb, Michel R. Klein, Marielle C. Haks, Kees L. M. C. Franken, Annemieke Geluk, Krista E. van Meijgaarden, Simone A. Joosten, Moses Joloba, Sarah Zalwango, Mary Nsereko, Brenda Okwera, Hussein Kisingo, Robert Golinski, Marc Jacobson, Hazel Dockrell, Steven Smith, Patricia Gorak-Stolinska, Yun-Gyoung Hur, Maeve Lalor, Ji-Sook Lee, Amelia C. Crampin, Neil French, Bagrey Ngwira, Anne Ben-Smith, Kate Watkins, Lyn Ambrose, Felanji Simukonda, Hazzie Mvula, Femia Chilongo, Jacky Saul, Keith Branson, Hassan Mahomed, Nicole Bilek, Onke Xasa, Ashley Veldsman, Michelle Fisher, Humphrey Mulenga, Brian Abel, Mark Bowmaker, Benjamin Kagina, William Kwong Chung, Jerry Sadoff, Donata Sizemore, S. Ramachandran, Lew Barker, Michael Brennan, Frank Weichold, Stefanie Muller, Larry Geiter, Desta Kassa, Almaz Abebe, Tsehayenesh Mesele, Belete Tegbaru, Debbie van Baarle, Frank Miedema, Adane Mihret, Abraham Aseffa, Yonas Bekele, Rachel Iwnetu, Mesfin Tafesse, Lawrence Yamuah, Martin Ota, Philip Hill, Richard Adegbola, Tumani Corrah, Martin Antonio, Toyin Togun, Ifedayo Adetifa, Peter Andersen, Ida Rosenkrands, Mark Doherty, Karin Weldingh, Gary Schoolnik, Gregory Dolganov, Tran Van, Fazlin Kafaar, Leslie Workman, Yolundi Cloete, Deborah Abrahams, Sizulu Moyo, Sebastian Gelderbloem, Michele Tameris, Hennie Geldenhuys, Willem Hanekom, Gregory Hussey, Rodney Ehrlich, Suzanne Verver

Publikováno v: American journal of respiratory and critical care medicine, 197(9), 1198-1208. American Thoracic Society
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, 197(9), 1198. American Thoracic Society
American journal of respiratory and critical care medicine, vol 197, iss 9
American Journal of Respiratory and Critical Care Medicine, 197(9), 1198-1208

Rationale: Contacts of patients with tuberculosis (TB) constitute an important target population for preventive measures because they are at high risk of infection with Mycobacterium tuberculosis and progression to disease. Objectives: We investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918b39963924be0a306581252709d36a
https://pure.amc.nl/en/publications/fourgene-panafrican-blood-signature-predicts-progression-to-tuberculosis(040a7060-f30a-4cfa-a0f3-e5fd8d66f323).html

Diagnostic accuracy and clinical utility of a simplified low cost method of counting CD4 cells with flow cytometry in Malawi: diagnostic accuracy study

Autor: Joep J. van Oosterhout, Eduard E. Zijlstra, Calman A. MacLennan, Malcolm E. Molyneux, Sarah White, Michael K. P. Liu, Joseph Bwanali, Michael Moore, Mark T. Drayson, Felanji Simukonda

Publikováno v: BMJ. 335:190-190

To assess the diagnostic accuracy and clinical utility of a simplified low cost method for measuring absolute and percentage CD4 counts with flow cytometry.A CD4 counting method (Blantyre count) using a CD4 and CD45 antibody combination with reduced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775380682c99ce27246f6f347ce27072
https://doi.org/10.1136/bmj.39268.719780.be