Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Feisi Liang"'
Publikováno v:
eLife, Vol 5 (2016)
Injured mature CNS axons do not regenerate in mammals. Deletion of PTEN, the negative regulator of PI3K, induces CNS axon regeneration through the activation of PI3K-mTOR signaling. We have conducted an extensive molecular dissection of the cross-reg
Externí odkaz:
https://doaj.org/article/41f85a7f6f8a4c929b31cb165b2faf72
Autor:
William H. Ridder, Weidong Xiao, Shaohua Li, Yang Hu, Qizhao Wang, Haoliang Huang, Lin Xu, Dong Feng Chen, Xiuyin Teng, Randal J. Kaufman, Linqing Miao, Liu Yang, Toby A. Ferguson, Feisi Liang
Publikováno v:
The Journal of Neuroscience. 36:5891-5903
Axon injury is an early event in neurodegenerative diseases that often leads to retrograde neuronal cell death and progressive permanent loss of vital neuronal functions. The connection of these two obviously sequential degenerative events, however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605875ce14fbcf74e81ae12a04398976
https://doi.org/10.1523/jneurosci.3709-15.2016
https://doi.org/10.1523/jneurosci.3709-15.2016
Autor:
Yang Sun, Linqing Miao, Feisi Liang, Yang Hu, Pei Zhuang, Haoliang Huang, Qizhao Wang, Liu Yang
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 3, Pp 1-9 (2019)
Cell Death and Disease, Vol 10, Iss 3, Pp 1-9 (2019)
Phosphatase and tensin homolog (PTEN) acts as a brake for the phosphatidylinositol 3-kinase–AKT–mTOR complex 1 (mTORC1) pathway, the deletion of which promotes potent central nervous system (CNS) axon regeneration. Previously, we demonstrated tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70eff118f130e43c30ec29df50e0aba2
https://pubmed.ncbi.nlm.nih.gov/30814515
https://pubmed.ncbi.nlm.nih.gov/30814515
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife
Injured mature CNS axons do not regenerate in mammals. Deletion of PTEN, the negative regulator of PI3K, induces CNS axon regeneration through the activation of PI3K-mTOR signaling. We have conducted an extensive molecular dissection of the cross-reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d620f4adce06760a7dfce4c026abff
https://doi.org/10.7554/elife.14908
https://doi.org/10.7554/elife.14908
Publikováno v:
Molecular Therapy. 24:S107-S108
Injuries of mature central nervous system (CNS) axons result in loss of vital functions due to the failure of CNS axons to regenerate. AKT, a family of serine/threonine-specific protein kinases, induces CNS axon regeneration through activation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::343a97d98ff5964080622fabf4041ff7
https://doi.org/10.1016/s1525-0016(16)33080-5
https://doi.org/10.1016/s1525-0016(16)33080-5
Autor:
Linqing Miao, Feisi Liang, Xiaodong Liu, Yang Hu, Kenneth S. Shindler, Yang Sun, Haoliang Huang, William H. Ridder, Qizhao Wang, Lin Xu, Xiuyin Teng
Publikováno v:
Cell Death & Disease
No therapies exist to prevent neuronal deficits in multiple sclerosis (MS), because the molecular mechanism responsible for the progressive neurodegeneration is unknown. We previously showed that axon injury-induced neuronal endoplasmic reticulum (ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf10f31bef0f22126e61ee3523594ce
https://doi.org/10.1038/cddis.2017.329
https://doi.org/10.1038/cddis.2017.329
Autor:
Jaloliddin Nuriddinov, Feisi Liang, Michael E. Selzer, Yang Hu, Xiuyin Teng, Haoliang Huang, Liu Yang, Shaohua Li, Linqing Miao
Publikováno v:
Nature communications
Using mouse optic nerve (ON) crush as a CNS injury model, we and others have found that activation of the mammalian target of rapamycin complex 1 (mTORC1) in mature retinal ganglion cells by deletion of the negative regulators, phosphatase and tensin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ff2a0f3eb94b78127867e5051a912f
https://doi.org/10.1038/ncomms6416
https://doi.org/10.1038/ncomms6416
Autor:
Liu Yang, Shaohua Li, Linqing Miao, Haoliang Huang, Feisi Liang, Xiuyin Teng, Lin Xu, Qizhao Wang, Weidong Xiao, Ridder III, William H., Ferguson, Toby A., Dong Feng Chen, Kaufman, Randal J., Yang Hu
Publikováno v:
Journal of Neuroscience; 5/25/2016, Vol. 36 Issue 21, p5891-5903, 13p