Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Feimei Kuang"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Alkaliptosis is a recently discovered type of pH-dependent cell death used for tumor therapy. However, its underlying molecular mechanisms and regulatory networks are largely unknown. Here, we report that the acetate-activating enzyme acetyl
Externí odkaz:
https://doaj.org/article/2411754a82c148c691fdabbb86a40bf2
Autor:
Jiao Liu, Xinxin Song, Feimei Kuang, Qiuhong Zhang, Yangchun Xie, Rui Kang, Guido Kroemer, Daolin Tang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Ferroptosis is an iron-dependent form of oxidative cell death. In this study, the authors show that NUPR1, a stress-inducible transcription factor, may be a driver of ferroptosis resistance.
Externí odkaz:
https://doaj.org/article/e835501ea437485f9ad64815cd003830
Publikováno v:
Journal of Pancreatology, Vol 3, Iss 3, Pp 154-160 (2020)
Abstract. Ferroptosis is a oxidative damage-dependent form of regulated cell death that has become an emerging target for disease prevention and treatment. Here, we show that dual-specificity phosphatase 1 (DUSP1), a phosphatase playing multiple role
Externí odkaz:
https://doaj.org/article/692a4ef90e154584b3efeda4824a0466
Autor:
Xinxin Song, Jiao Liu, Feimei Kuang, Xin Chen, Herbert J. Zeh, III, Rui Kang, Guido Kroemer, Yangchun Xie, Daolin Tang
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108767- (2021)
Summary: Although induction of ferroptosis, an iron-dependent form of non-apoptotic cell death, has emerged as an anticancer strategy, the metabolic basis of ferroptotic death remains poorly elucidated. Here, we show that glucose determines the sensi
Externí odkaz:
https://doaj.org/article/2275ec8fa8824df9918532d28b450b92
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Many new types of regulated cell death have been recently implicated in human health and disease. These regulated cell deaths have different morphological, genetic, biochemical, and functional hallmarks. Ferroptosis was originally described as a carc
Externí odkaz:
https://doaj.org/article/ccd1c48e1aec458394aa8ef90aad9063
Publikováno v:
Journal of Pancreatology, Vol 3, Iss 3, Pp 154-160 (2020)
Ferroptosis is a oxidative damage-dependent form of regulated cell death that has become an emerging target for disease prevention and treatment. Here, we show that dual-specificity phosphatase 1 (DUSP1), a phosphatase playing multiple roles in stres
Autor:
Xinxin Song, Guido Kroemer, Yangchun Xie, Qiuhong Zhang, Daolin Tang, Feimei Kuang, Jiao Liu, Rui Kang
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.647. ⟨10.1038/s41467-021-20904-2⟩
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, 2021, 12 (1), pp.647. ⟨10.1038/s41467-021-20904-2⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.647. ⟨10.1038/s41467-021-20904-2⟩
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, 2021, 12 (1), pp.647. ⟨10.1038/s41467-021-20904-2⟩
Ferroptosis is a type of iron-dependent regulated cell death, representing an emerging disease-modulatory mechanism. Transcription factors play multiple roles in ferroptosis, although the key regulator for ferroptosis in iron metabolism remains elusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c684084f5ff58070a4ab6f1c6f3857
https://hal.sorbonne-universite.fr/hal-03127104/file/s41467-021-20904-2.pdf
https://hal.sorbonne-universite.fr/hal-03127104/file/s41467-021-20904-2.pdf
Publikováno v:
Cancer Gene Therapy. 27:267-269
Malignant tumors are one of the major causes of death worldwide, and the development of better treatments is urgently needed. There are many types of cancer treatment, such as surgery, chemotherapy, radiation therapy, immunotherapy, and targeted ther
Autor:
Xinxin Song, Xin Chen, Feimei Kuang, Daolin Tang, Herbert J. Zeh, Jiao Liu, Rui Kang, Guido Kroemer, Yangchun Xie
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108767-(2021)
Cell Reports
Cell Reports, Elsevier Inc, 2021, 34 (8), pp.108767. ⟨10.1016/j.celrep.2021.108767⟩
Cell Reports, 2021, 34 (8), pp.108767. ⟨10.1016/j.celrep.2021.108767⟩
Cell Reports
Cell Reports, Elsevier Inc, 2021, 34 (8), pp.108767. ⟨10.1016/j.celrep.2021.108767⟩
Cell Reports, 2021, 34 (8), pp.108767. ⟨10.1016/j.celrep.2021.108767⟩
International audience; Although induction of ferroptosis, an iron-dependent form of non-apoptotic cell death, has emerged as an anticancer strategy, the metabolic basis of ferroptotic death remains poorly elucidated. Here, we show that glucose deter
Publikováno v:
Cell Chemical Biology. 28:765-775.e5
Ferroptosis is a type of nonapoptotic cell death driven by lipid peroxidation. Here, we show a key role of MGST1 in inhibiting ferroptosis in cell cultures and mouse xenograft models. Ferroptosis activators induce MGST1 upregulation in human pancreat