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Akademický článek

Houttuynia cordata Thunb. and its bioactive compound 2-undecanone significantly suppress benzo(a)pyrene-induced lung tumorigenesis by activating the Nrf2-HO-1/NQO-1 signaling pathway

Autor: Yanmei Lou, Zhenzhen Guo, Yuanfeng Zhu, Muyan Kong, Rongrong Zhang, Linlin Lu, Feichi Wu, Zhongqiu Liu, Jinjun Wu

Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-21 (2019)

Abstract Background Lung cancer remains the most common cause of cancer-related deaths, with a high incidence and mortality in both sexes worldwide. Chemoprevention has been the most effective strategy for lung cancer prevention. Thus, exploring nove

Externí odkaz: https://doaj.org/article/0724fad6fdea49bfb2aba8ad29d5e013

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Akademický článek

An Ultra-High Performance Liquid Chromatographic-Tandem Mass Spectrometric Method for the Determination of Sinomenine in Human Plasma after Transdermal Delivery of the Zhengqing Fengtongning Injection

Autor: Tingbo Chen, Zheng Xiang, Gengting Dong, Pei Luo, Ping Qiu, Shenzhi Wang, Baoming Huang, Yingyi Wen, Feichi Wu, Liang Liu, Hua Zhou

Publikováno v: Molecules, Vol 20, Iss 4, Pp 6454-6465 (2015)

A sensitive, precise and selective ultra-high performance liquid chromatography method coupled with triple-quadrupole mass spectrometry was developed and validated for the determination of trace amounts of sinomenine (ng/mL) in minute volumes of huma

Externí odkaz: https://doaj.org/article/24610bd9cad54decb4000e3288c29846

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Houttuynia cordata Thunb. and its bioactive compound 2-undecanone significantly suppress benzo(a)pyrene-induced lung tumorigenesis by activating the Nrf2-HO-1/NQO-1 signaling pathway

Autor: Zhongqiu Liu, Muyan Kong, Lu Linlin, Rong-Rong Zhang, Jinjun Wu, Zhenzhen Guo, Yuanfeng Zhu, Yanmei Lou, Feichi Wu

Publikováno v: Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-21 (2019)

Background Lung cancer remains the most common cause of cancer-related deaths, with a high incidence and mortality in both sexes worldwide. Chemoprevention has been the most effective strategy for lung cancer prevention. Thus, exploring novel and eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ca53758e0be591d7a0aec726fcbdb9
https://pubmed.ncbi.nlm.nih.gov/31174565

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Additional file 1: of Houttuynia cordata Thunb. and its bioactive compound 2-undecanone significantly suppress benzo(a)pyrene-induced lung tumorigenesis by activating the Nrf2-HO-1/NQO-1 signaling pathway

Autor: Yanmei Lou, Zhenzhen Guo, Yuanfeng Zhu, Muyan Kong, Rongrong Zhang, Linlin Lu, Feichi Wu, Zhongqiu Liu, Jinjun Wu

Figure S1. The GC-FID chromatogram of standard compound 2-undecanone (A) and H.cordata water extract (B). Figure S2. Representative images showing haematoxylin and eosin staining of lung samples from the different groups. Figure S3. Effects of B[a]P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9c0c9568ebce821f99e3fba31cc8b5

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Sinomenine, an Antirheumatic Alkaloid, Ameliorates Clinical Signs of Disease in the Lewis Rat Model of Acute Experimental Autoimmune Encephalolmyelitis

Autor: Bingjie Gu, Xin-Sheng Ding, Feichi Wu, Yanying Zeng, Xiaohui Ji, Chunjie Song

Publikováno v: Biological and Pharmaceutical Bulletin. 30:1438-1444

The therapeutic value of an antirheumatic alkaloid, sinomenine (SIN), was investigated in the acute experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS). SIN is a bioactive alkaloid derived from the Chinese medicinal plant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f6b1ff9b19de33d407cd36d256ab8c
https://doi.org/10.1248/bpb.30.1438

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