Radiation-Sensitising Effects of Antennapedia Proteins (ANTP)-SmacN7 on Tumour Cells

Autor: Chang Xu, Takanori Katsube, Jia Cao, Hui Zhao, Bing Wang, Sai Jun Fan, Qiang Liu, Yan Wang, Fei Yue Fan, Qin Wang, Li Qing Du

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 14; Issue 12; Pages: 24087-24096
International Journal of Molecular Sciences, Vol 14, Iss 12, Pp 24087-24096 (2013)

The objective of this study was to investigate the underlying mechanisms behind the radiation-sensitising effects of the antennapedia proteins (ANTP)-smacN7 fusion protein on tumour cells. ANTP-SmacN7 fusion proteins were synthesised, and the ability

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030229c0d38d88cd055e2e9eb306dfdf
https://doi.org/10.3390/ijms141224087

Evaluation of the Comet Assay for Assessing the Dose-Response Relationship of DNA Damage Induced by Ionizing Radiation

Autor: Yan, Wang（王 彦）, Chang, Xu（徐 暢）, Li, Qing Du（杜 利清）, Jia, Cao （曹 佳）, Jian, Xiang Liu（劉 建香）, Xu, Su（蘇 旭）, Hui, Zhao（趙 輝）, Fei-Yue, Fan（樊 飛躍）, Wang, Bing, Katube, Takanori, Sai, Jun Fan（樊 賽軍）, Qiang, Liu（劉 強）

Publikováno v: International Journal of Molecular Sciences.. 14(11):22449-22461

Dose- and time-response curves were combined to assess the potential of the comet assay in radiation biodosimetry. The neutral comet assay was used to detect DNA double-strand breaks in lymphocytes caused by γ-ray irradiation. A clear dose-response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::76a51860045463dfabf832445f933039
https://repo.qst.go.jp/records/46666

Expression of miRNA-130a in Nonsmall Cell Lung Cancer

Autor: Meng Aimin, Li-Li Tian, Du Liqing, Hongying Wu, Deguan Li, Xiaoyan Jiang, Heng Zhang, Yi She, Qing-Fen Liu, Yueying Wang, Hai-Liang Wu, Fei-Yue Fan, Xiao-Chun Wang

Publikováno v: The American Journal of the Medical Sciences. 340:385-388

MicroRNAs are short regulatory RNAs that negatively modulate gene expression at the posttranscriptional level and are deeply involved in the pathogenesis of several types of cancer. The miRNA-130a has been shown to play a role in antagonizing the inh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff566de7409709b5926b3caa1c6e17c
https://doi.org/10.1097/maj.0b013e3181e892a0

Aurora-A interacts with Cyclin B1 and enhances its stability

Autor: Lili Qin, Fei-Yue Fan, Liyan Xue, Qimin Zhan, Yongmei Song, Tong Tong

Publikováno v: Cancer Letters. 275:77-85

The mitotic regulator Aurora-A is an oncogenic protein that is over-expressed in many types of human tumors. However, the underlying mechanism through which Aurora-A promotes tumorigenesis remains unclear. Here, we show that overexpression of Aurora-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10afa9e4cecfe8e8fa73b94ea141d57d
https://doi.org/10.1016/j.canlet.2008.10.011

Overexpression of Aurora-A kinase promotes tumor cell proliferation and inhibits apoptosis in esophageal squamous cell carcinoma cell line

Autor: Shun Qian Jin, Rong Liu, Qi Min Zhan, Fei Yue Fan, Xiaoxia Wang

Publikováno v: Cell Research. 16:356-366

Aurora-A kinase, a serine/threonine protein kinase, is a potential oncogene. Amplification and overexpression of Aurora-A have been found in several types of human tumors, including esophageal squamous cell carcinoma (ESCC). It has been demonstrated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc632931cee3b9b41bfe65f5f1cacf7c
https://doi.org/10.1038/sj.cr.7310046