Local estrogen metabolism in epithelial ovarian cancer suggests novel targets for therapy

Autor: Ren, Xia, Wu, Xuan, Hillier, Stephen G., Fegan, K. Scott, Critchley, Hilary O.D., Mason, J. Ian, Sarvi, Sana, Harlow, Christopher R.

Publikováno v: Ren, X, Wu, X, Hillier, S G, Fegan, K S, Critchley, H O D, Mason, J I, Sarvi, S & Harlow, C R 2015, ' Local estrogen metabolism in epithelial ovarian cancer suggests novel targets for therapy ', Journal of Steroid Biochemistry and Molecular Biology, vol. 150, pp. 54-63 . https://doi.org/10.1016/j.jsbmb.2015.03.010

Epithelial ovarian cancer (EOC) accounts for about 90% of malignant ovarian tumors, and estrogen is often implicated in disease progression. We therefore compared the potential for gating of estrogen action via pre-receptor metabolism in normal human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d1f70c0d8a1d1fa82ef3811c0dbc2424
https://hdl.handle.net/20.500.11820/897672b6-a6db-4fc6-b377-d0bbcc5841f3

Regulation of 3β-hydroxysteroid dehydrogenase type 1 and type 2 gene expression and function in the human ovarian surface epithelium by cytokines.

Autor: Papacleovoulou, Georgia, Hogg, Kirsten, Fegan, K. Scott, Critchley, Hilary O.D., Hillier, Stephen G., Mason, J. Ian

Publikováno v: Molecular Human Reproduction; Jun2009, Vol. 15 Issue 6, p379-392, 14p

Oral contraceptive use and cancer: final report from the Oxford--Family Planning Association contraceptive study.

Autor: Fegan, K. Scott

Publikováno v: Journal of Family Planning & Reproductive Health Care; Apr2014, Vol. 40 Issue 2, p112-112, 1/2p