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pro vyhledávání: '"Fee Werner"'
Publikováno v:
Matrix Proteases in Health and Disease
Autor:
Sebastian Müller, Uta Schurigt, Thomas Reinheckel, Mieczyslaw Gajda, Marie Follo, C Sieber, Lisa Sevenich, Fee Werner, Christoph Peters
Publikováno v:
Oncogene; Vol 30
Oncogene
Oncogene
Elevated expression of the cysteine protease cathepsin B (CTSB) has been correlated with a poor prognosis for cancer patients. In order to model high CTSB expression in mammary cancer, transgenic mice expressing human CTSB were crossed with transgeni
Autor:
Thomas Reinheckel, Dominik von Elverfeldt, Mieczyslaw Gajda, Uta Schurigt, Andreas Stahl, Anne-Katrin Becker, Corinne Vannier, Anne Schwinde, Lisa Sevenich, Fee Werner, Matthew Bogyo, Christoph Peters
Publikováno v:
Biological Chemistry. :080808065201770-21
Recent data suggest proteases of the papain-like cysteine cathepsin family as molecular targets for cancer therapy. Here, we report the treatment of polyoma middle T oncogene-induced breast cancers in mice with the cell-permeable broad-spectrum cyste