Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Fee L, Romunde"'
Autor:
Yuan Ji, Marlieke G. Veldhuis, Jantien Zandvoort, Fee L. Romunde, Marien J. C. Houtman, Karen Duran, Gijs van Haaften, Eva-Maria Zangerl-Plessl, Hiroki Takanari, Anna Stary-Weinzinger, Marcel A. G. van der Heyden
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-10 (2017)
Abstract Background The inward rectifier potassium current IK1 contributes to a stable resting membrane potential and phase 3 repolarization of the cardiac action potential. KCNJ2 gain-of-function mutations V93I and D172N associate with increased IK1
Externí odkaz:
https://doaj.org/article/efbd78c2599d487c96e896e9cb6f2763
Autor:
Yuan, Ji, Hiroki, Takanari, Muge, Qile, Lukas, Nalos, Marien J C, Houtman, Fee L, Romunde, Raimond, Heukers, Paul M P, van Bergen En Henegouwen, Marc A, Vos, Marcel A G, van der Heyden
Publikováno v:
Journal of Cellular and Molecular Medicine
Drug‐induced ion channel trafficking disturbance can cause cardiac arrhythmias. The subcellular level at which drugs interfere in trafficking pathways is largely unknown. KIR2.1 inward rectifier channels, largely responsible for the cardiac inward