Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells

Autor: Riemann, Marc, Andreas, Nico, Fedoseeva, Maria, Meier, Elke, Weih, Debra, Freytag, Helga, Schmidt-Ullrich, Ruth, Klein, Ulf, Wang, Zhao-Qi, Weih, Falk

Publikováno v: In Journal of Autoimmunity July 2017 81:56-67

The microbiota regulates type 2 immunity through RORγt + T cells

Autor: Ohnmacht, Caspar, Park, Joo-Hong, Cording, Sascha, Wing, James B., Atarashi, Koji, Obata, Yuuki, Gaboriau-Routhiau, Valérie, Marques, Rute, Dulauroy, Sophie, Fedoseeva, Maria, Busslinger, Meinrad, Cerf-Bensussan, Nadine, Boneca, Ivo G., Voehringer, David, Hase, Koji, Honda, Kenya, Sakaguchi, Shimon, Eberl, Gérard

Publikováno v: Science, 2015 Aug . 349(6251), 989-993.

Externí odkaz: http://www.jstor.org/stable/24749249

MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells.

Autor: Ohnmacht C; Institut Pasteur, Microenvironment and Immunity Unit, 75724 Paris, France., Park JH; Institut Pasteur, Microenvironment and Immunity Unit, 75724 Paris, France., Cording S; Institut Pasteur, Microenvironment and Immunity Unit, 75724 Paris, France., Wing JB; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Suita 565-0871, Japan., Atarashi K; RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Yokohama, Kanagawa 230-0045, Japan. PRESTO, Japan Science and Technology Agency, Saitama 332-0012, Japan., Obata Y; The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan., Gaboriau-Routhiau V; INSERM, U1163, Laboratory of Intestinal Immunity, Paris, France. Université Paris Descartes-Sorbonne Paris Cité and Institut Imagine, Paris, France. INRA Micalis UMR1319, Jouy-en-Josas, France., Marques R; Institut Pasteur, Microenvironment and Immunity Unit, 75724 Paris, France., Dulauroy S; Institut Pasteur, Microenvironment and Immunity Unit, 75724 Paris, France., Fedoseeva M; Center of Allergy and Environment (ZAUM), Technische Universität and Helmholtz Zentrum München, Munich, Germany., Busslinger M; Research Institute of Molecular Pathology, Vienna Biocenter, 1030 Vienna, Austria., Cerf-Bensussan N; INSERM, U1163, Laboratory of Intestinal Immunity, Paris, France. Université Paris Descartes-Sorbonne Paris Cité and Institut Imagine, Paris, France., Boneca IG; Institut Pasteur, Biology and Genetics of Bacterial Cell Wall, 75724 Paris, France. INSERM, Groupe Avenir, 75015 Paris, France., Voehringer D; Department of Infection Biology at the Institute of Clinical Microbiology, Immunology and Hygiene, University Clinic Erlangen and Friedrich-Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany., Hase K; The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan., Honda K; RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Yokohama, Kanagawa 230-0045, Japan. CREST, Japan Science and Technology Agency, 4-1-8 Honcho Kawaguchi, Saitama 332-0012, Japan., Sakaguchi S; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Suita 565-0871, Japan. Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan., Eberl G; Institut Pasteur, Microenvironment and Immunity Unit, 75724 Paris, France. gerard.eberl@pasteur.fr.

Publikováno v: Science (New York, N.Y.) [Science] 2015 Aug 28; Vol. 349 (6251), pp. 989-93. Date of Electronic Publication: 2015 Jul 09.