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An integrated approach for early in vitro seizure prediction utilizing hiPSC neurons and human ion channel assays.

Autor: Rockley, Kimberly, Roberts, Ruth, Jennings, Hannah, Jones, Karen, Davis, Myrtle, Levesque, Paul, Morton, Michael

Publikováno v: Toxicological Sciences; Nov2023, Vol. 196 Issue 1, p126-140, 15p

Complement tunes glutamate release and supports synaptic impairments in an animal model of multiple sclerosis.

Autor: Olivero G; Department of Pharmacy, DIFAR, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy., Taddeucci A; Department of Pharmacy, DIFAR, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy., Vallarino G; Department of Pharmacy, DIFAR, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy., Trebesova H; Department of Pharmacy, DIFAR, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy., Roggeri A; Department of Pharmacy, DIFAR, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy., Gagliani MC; DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Laboratory, Università di Genova, Genoa, Italy., Cortese K; DIMES, Department of Experimental Medicine, Cellular Electron Microscopy Laboratory, Università di Genova, Genoa, Italy., Grilli M; Department of Pharmacy, DIFAR, Pharmacology and Toxicology Section, University of Genoa, Genoa, Italy., Pittaluga A; Department of Pharmacy, DIFAR, Pharmacology and Toxicology Section, Centre of Excellence for Biomedical Research, 3Rs Center, University of Genoa, Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Jun; Vol. 181 (12), pp. 1812-1828. Date of Electronic Publication: 2024 Feb 18.

A multimodal, implantable sensor array and measurement system to investigate the suppression of focal epileptic seizure using hypothermia.

Autor: Csernyus, B, Szabó, Á, Fiáth, R, Zátonyi, A, Lázár, C, Pongrácz, A, Fekete, Z

Publikováno v: Journal of Neural Engineering; Aug2021, Vol. 18 Issue 4, p1-14, 14p