Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Fedir, Bokhovchuk"'
Autor:
Yannick Mesrouze, Gustavo Aguilar, Marco Meyerhofer, Fedir Bokhovchuk, Catherine Zimmermann, Patrizia Fontana, Alexandra Vissières, Hans Voshol, Dirk Erdmann, Markus Affolter, Patrick Chène
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract The TEAD transcription factors are the most downstream elements of the Hippo pathway. Their transcriptional activity is modulated by different regulator proteins and by the palmitoylation/myristoylation of a specific cysteine residue. In thi
Externí odkaz:
https://doaj.org/article/f02b86fa3df24797a39ed636e8605ba1
Autor:
Michael Feichtinger, Andreas Beier, Mario Migotti, Matthias Schmid, Fedir Bokhovchuk, Patrick Chène, Robert Konrat
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104099- (2022)
Summary: Yes-associated protein (YAP) is a partly intrinsically disordered protein (IDP) that plays a major role as the downstream element of the Hippo pathway. Although the structures of the complex between TEA domain transcription factors (TEADs) a
Externí odkaz:
https://doaj.org/article/29d36cbaa80447f8b4aa1c02d947df57
Akademický článek
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Autor:
Fedir Bokhovchuk, Yannick Mesrouze, Marco Meyerhofer, Patrizia Fontana, Catherine Zimmermann, Frédéric Villard, Dirk Erdmann, Joerg Kallen, Clemens Scheufler, Camilo Velez‐Vega, Patrick Chène
Publikováno v:
Protein science : a publication of the Protein Society. 32(1)
The yes-associated protein (YAP) regulates the transcriptional activity of the TEAD transcription factors that are key in the control of organ morphogenesis. YAP interacts with TEAD via three secondary structure elements: a β-strand, an α-helix, an
Autor:
Yannick Mesrouze, Fedir Bokhovchuk, Marco Meyerhofer, Patrizia Fontana, Catherine Zimmermann, Typhaine Martin, Clara Delaunay, Dirk Erdmann, Tobias Schmelzle, Patrick Chène
Publikováno v:
eLife, Vol 6 (2017)
TEAD (TEA/ATTS domain) transcription factors are the most distal effectors of the Hippo pathway. YAP (Yes-associated protein) is a coactivator protein which, upon binding to TEAD proteins, stimulates their transcriptional activity. Since the Hippo pa
Externí odkaz:
https://doaj.org/article/bd70a4e9206a4019ba44712c116f4c9f
Autor:
Fedir Bokhovchuk, Thomas Vorherr, Catherine Zimmermann, Frederic Villard, Tobias Schmelzle, Patrizia Fontana, Patrick Chène, Marco Meyerhofer, Clara Delaunay, Roman Wille, Yannick Mesrouze, Markus Affolter, Dirk Erdmann, Typhaine Martin, Clemens Scheufler, Pascal Furet, Gustavo Aguilar
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
The most downstream elements of the Hippo pathway, the TEAD transcription factors, are regulated by several cofactors, such as Vg/VGLL1-3. Earlier findings on human VGLL1 and here on human VGLL3 show that these proteins interact with TEAD via a conse
Autor:
Fedir, Bokhovchuk, Yannick, Mesrouze, Marco, Meyerhofer, Patrizia, Fontana, Catherine, Zimmermann, Frédéric, Villard, Dirk, Erdmann, Joerg, Kallen, Clemens, Scheufler, Camilo, Velez‐Vega, Patrick, Chène
Publikováno v:
Protein Science: A Publication of the Protein Society; Jan2023, Vol. 32 Issue 1, p1-13, 13p
Autor:
Patrizia Fontana, Clemens Scheufler, Tobias Schmelzle, Typhaine Martin, Dirk Erdmann, Frederic Villard, Clara Delaunay, Pascal Furet, Yannick Mesrouze, Catherine Zimmermann, Marco Meyerhofer, Patrick Chène, Fedir Bokhovchuk
Publikováno v:
Protein Sci
The Hippo pathway is a key signaling pathway in the control of organ size and development. The most distal elements of this pathway, the TEAD transcription factors, are regulated by several proteins, such as YAP (Yes‐associated protein), TAZ (trans
Autor:
Dirk Erdmann, Patrick Chène, Tobias Schmelzle, Patrizia Fontana, Joerg Kallen, Yannick Mesrouze, Fedir Bokhovchuk, Catherine Zimmermann, Pascal Furet, Marco Meyerhofer, Aude Izaac
Publikováno v:
Protein Science. 27:1810-1820
Autor:
Patrizia Fontana, Yannick Mesrouze, Patrick Chène, Fedir Bokhovchuk, Dirk Erdmann, Marco Meyerhofer, Catherine Zimmermann
Publikováno v:
Protein Science : A Publication of the Protein Society
The Hippo signaling pathway, which plays a central role in the control of organ size in animals, is well conserved in metazoans. The most downstream elements of this pathway are the TEAD transcription factors that are regulated by their association w