Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Federico W. Grillo"'
Autor:
Mark Rigby, Federico W. Grillo, Benjamin Compans, Guilherme Neves, Julia Gallinaro, Sophie Nashashibi, Sally Horton, Pedro M. Pereira Machado, Maria Alejandra Carbajal, Gema Vizcay-Barrena, Florian Levet, Jean-Baptiste Sibarita, Angus Kirkland, Roland A. Fleck, Claudia Clopath, Juan Burrone
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112397- (2023)
Summary: Excitatory synapses are typically described as single synaptic boutons (SSBs), where one presynaptic bouton contacts a single postsynaptic spine. Using serial section block-face scanning electron microscopy, we found that this textbook defin
Externí odkaz:
https://doaj.org/article/9fe2dcf6007c438582d9f4154a119fe9
Autor:
Agata Kranjc, Federico W Grillo, Juraj Rievaj, Anna Boccaccio, Fabio Pietrucci, Anna Menini, Paolo Carloni, Claudio Anselmi
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4672 (2009)
Bestrophins are a recently discovered family of Cl(-) channels, for which no structural information is available. Some family members are activated by increased intracellular Ca2+ concentration. Bestrophins feature a well conserved Asp-rich tract in
Externí odkaz:
https://doaj.org/article/b5372c9801fb4120aad2f414c9804251
Autor:
Federico W. Grillo
Publikováno v:
Journal of Chemical Neuroanatomy. 76:28-34
All animals have to find the right balance between investing resources into their reproductive cycle and protecting their tissues from age-related damage. In higher order organisms the brain is particularly vulnerable to ageing, as the great majority
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e707a14577541e90fb3f7fe38dcfcd70
https://doi.org/10.1016/j.jchemneu.2015.12.005
https://doi.org/10.1016/j.jchemneu.2015.12.005
Autor:
Anne Jorstad, Federico W. Grillo, Bohumil Maco, Corrado Calì, Vincenzo De Paola, Marta Wawrzyniak, Pascal Fua, Graham Knott, Carlos Becker, Biagio Nigro, Marco Cantoni
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0198131 (2018)
PLoS ONE
PLoS ONE
This study has used dense reconstructions from serial EM images to compare the neuropil ultrastructure and connectivity of aged and adult mice. The analysis used models of axons, dendrites, and their synaptic connections, reconstructed from volumes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c138770d9e420b0679fe8adca8cd4125
http://europepmc.org/articles/PMC6028106?pdf=render
http://europepmc.org/articles/PMC6028106?pdf=render
Publikováno v:
Neuroinformatics. 14:121-127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca4070fc7b79f7dbbd1b3b0a024cb48e
https://doi.org/10.1007/s12021-015-9274-5
https://doi.org/10.1007/s12021-015-9274-5
Autor:
Federico W, Grillo, Guilherme, Neves, Alison, Walker, Gema, Vizcay-Barrena, Roland A, Fleck, Tiago, Branco, Juan, Burrone
Publikováno v:
Neuron
Summary How presynaptic inputs and neurotransmitter release dynamics are distributed along a dendritic tree is not well established. Here, we show that presynaptic boutons that form onto basal dendrites of CA1 pyramidal neurons display a decrease in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c417a04a76e48504d130dfd6c6e1af5a
https://pubmed.ncbi.nlm.nih.gov/29983327
https://pubmed.ncbi.nlm.nih.gov/29983327
Autor:
Gema Vizcay-Barrena, Mark Rigby, Cian O'Donnell, Roland A. Fleck, Federico W. Grillo, Juan Burrone, Andrew S. Lowe, Alison S. Walker, Guilherme Neves, Rachel E. Jackson
Publikováno v:
Walker, A S, Neves, G, Grillo, F, Jackson, R E, Rigby, M, O'Donnell, C, Lowe, A S, Vizcay-Barrena, G, Fleck, R A & Burrone, J 2017, ' Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites ', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 10, pp. 1986-1995 . https://doi.org/10.1073/pnas.1607462114
Walker, A S, Neves, G, Grillo, F, Jackson, R E, Rigby, M, O'Donnell, C, Lowe, A S, Vizcay-Barrena, G, Fleck, R A & Burrone, J 2017, ' Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites ', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 10, pp. E1986-E1995 . https://doi.org/10.1073/pnas.1607462114
Walker, A S, Neves, G, Grillo, F, Jackson, R E, Rigby, M, O'Donnell, C, Lowe, A S, Vizcay-Barrena, G, Fleck, R A & Burrone, J 2017, ' Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites ', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 10, pp. E1986-E1995 . https://doi.org/10.1073/pnas.1607462114
Neurons receive a multitude of synaptic inputs along their dendritic arbor, but how this highly heterogeneous population of synaptic compartments is spatially organized remains unclear. By measuring N-methyl-d-aspartic acid receptor (NMDAR)-driven ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234472d8ca2a9dab10fa08b2374a35ce
https://pubmed.ncbi.nlm.nih.gov/28209776
https://pubmed.ncbi.nlm.nih.gov/28209776
Autor:
Katrin Amunts, Markus Axer, Kevin Beier, Peter Bloomfield, Denis Boire, Dirk Bucher, Alison J. Canty, Marie Carlén, C. Cebrián, Francisco Clascá, Markus Cremer, Christiaan P.J. de Kock, Vincenzo De Paola, Tim B. Dyrby, Timothy J. Edwards, Robert Egger, Marian Evangelio, Maria José Galazo, Ralf Galuske, David Gräßel, Federico W. Grillo, Giorgio M. Innocenti, Zoltán Kisvárday, Carol A. Mason, Ian O. Massé, E. Mengual, S. Mongia, Laura R. Morcom, Kensaku Mori, Farzad Mortazavi, Rajeevan T. Narayanan, Marcel Oberlaender, Nicola Palomero-Gallagher, André Parent, Martin Parent, César Porrero, L. Prensa, Philippe Régnier, Linda J. Richards, Alard Roebroeck, Douglas L. Rosene, Pablo Rubio-Garrido, Philipp Schlömer, Kerstin E. Schmidt, Arne Seehaus, Austen A. Sitko, A. Tripathi, Van J. Wedeen, Roger Woods, Karl Zilles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62bba8b8f73f71a4e313f3902a4c19ee
https://doi.org/10.1016/b978-0-12-801393-9.00025-6
https://doi.org/10.1016/b978-0-12-801393-9.00025-6
Charting the trajectory of individual axons within the intact central nervous system during development into maturity and into the normal aging process has long been the holy grail of neuroimaging. We review a range of approaches that have historical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5462815ff9aa08681ef8d30b235fb0d
https://doi.org/10.1016/b978-0-12-801393-9.00011-6
https://doi.org/10.1016/b978-0-12-801393-9.00011-6
Autor:
Nabil Hajji, Banafsheh Razzaghi, Vincent T. Cunliffe, Stjepana Kovac, Michelle L. Krishnan, Johan G. Eriksson, Maxime Rotival, Klaus Wanisch, Michele Simonato, Albert J. Becker, Manuel Mattheisen, Paolo Roncon, Enrico Petretto, Doug Speed, Aleksandra Dabrowska, Marc Chadeau-Hyam, Jacques Behmoaras, Terence J. O'Brien, Federico W. Grillo, Paola L. Meza Santoscoy, Matthew C. Walker, Sarah R. Langley, Manuela Mazzuferi, Rafal Kaminski, Patrik Foerch, Marvin Johnson, Tiziana Rossetti, Susanne Schoch, Per Hoffmann, Anna Slaviero, Leonardo Bottolo, Prashant K. Srivastava, Vincenzo De Paola, Tisham De, Sven Cichon, Katharina Pernhorst, Slavé Petrovski, Pitt Niehusmann, Marec von Lehe, Kirill Shkura, Alison J. Coffey, Bénédicte Danis
Publikováno v:
NATURE COMMUNICATIONS
Johnson, M R, Behmoaras, J, Bottolo, L, Krishnan, M L, Pernhorst, K, Santoscoy, P L M, Rossetti, T, Speed, D, Srivastava, P K, Chadeau-Hyam, M, Hajji, N, Dabrowska, A, Rotival, M, Razzaghi, B, Kovac, S, Wanisch, K, Grillo, F W, Slaviero, A, Langley, S R, Shkura, K, Roncon, P, De, T, Mattheisen, M, Niehusmann, P, O'Brien, T J, Petrovski, S, von Lehe, M, Hoffmann, P, Eriksson, J, Coffey, A J, Cichon, S, Walker, M, Simonato, M, Danis, B, Mazzuferi, M, Foerch, P, Schoch, S, De Paola, V, Kaminski, R M, Cunliffe, V T, Becker, A J & Petretto, E 2015, ' Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus ', Nature Communications, vol. 6, pp. 6031 . https://doi.org/10.1038/ncomms7031
Johnson, M R, Behmoaras, J, Bottolo, L, Krishnan, M L, Pernhorst, K, Santoscoy, P L M, Rossetti, T, Speed, D, Srivastava, P K, Chadeau-Hyam, M, Hajji, N, Dabrowska, A, Rotival, M, Razzaghi, B, Kovac, S, Wanisch, K, Grillo, F W, Slaviero, A, Langley, S R, Shkura, K, Roncon, P, De, T, Mattheisen, M, Niehusmann, P, O'Brien, T J, Petrovski, S, von Lehe, M, Hoffmann, P, Eriksson, J, Coffey, A J, Cichon, S, Walker, M, Simonato, M, Danis, B, Mazzuferi, M, Foerch, P, Schoch, S, De Paola, V, Kaminski, R M, Cunliffe, V T, Becker, A J & Petretto, E 2015, ' Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus ', Nature Communications, vol. 6, pp. 6031 . https://doi.org/10.1038/ncomms7031
Gene-regulatory network analysis is a powerful approach to elucidate the molecular processes and\ud pathways underlying complex disease. Here we employ systems genetics approaches to characterize the\ud genetic regulation of pathophysiological pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8aebdabacbf3d1d0a3d5f475acb7dc3
https://doi.org/10.1038/ncomms7031
https://doi.org/10.1038/ncomms7031