Zobrazeno 1 - 10
of 2 118
pro vyhledávání: '"Federico V"'
Autor:
Sandra Solaz, Elena Cardenal‐Muñoz, Alicia Muñoz, Simona Giorgi, Federico V. Pallardó, Carlos Romá‐Mateo, José Ángel Aibar
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1806-1815 (2024)
Abstract Objectives Dravet syndrome (DS) is a rare form of refractory epilepsy that begins in the first year of life. Approximately 85% of patients have a mutation in the SCN1A gene, which encodes a voltage‐gated sodium channel. The main objective
Externí odkaz:
https://doaj.org/article/c543f2f3de9046249ef6489227c98ab3
Autor:
Davinia Domínguez-González, Blanca Romero-Llopis, Marta Roldán-Lázaro, Lorena Baquero, Rita Noverques, Federico V Pallardó, Juan Antonio Navarro, Pilar Gonzalez-Cabo
Publikováno v:
Redox Experimental Medicine, Vol 2024, Iss 1, Pp 1-15 (2024)
l-glutamate is one of the major neurotransmitters in the central nervous system, directly and indirectly involved in numerous brain functions. In several neurodegenerative diseases, it has been observed that an excess of extracellular glutamate overs
Externí odkaz:
https://doaj.org/article/9761833eb5974421a19a478208ddbe52
Autor:
Marta Seco-Cervera, José Santiago Ibáñez-Cabellos, Federico V. Pallardo, José-Luis García-Giménez, Anna Aulinas, Luciana Martel-Duguech, Susan M. Webb, Elena Valassi
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionPatients with Cushing’s syndrome (CS) in remission show sustained fatigue, myopathy, and an increased prevalence of sarcopenia. The mechanisms that determine these persistent muscle problems are not well known. We aimed to identify circ
Externí odkaz:
https://doaj.org/article/5ece26e418bd4941ab70e0229556a348
Autor:
Jesús Beltrán-García, Germán Casabó-Vallés, Rebeca Osca-Verdegal, Paula Navarrete-López, María Rodriguez-Gimillo, Elena Nacher-Sendra, Carolina Ferrando-Sánchez, Eva García-López, Federico V. Pallardó, Nieves Carbonell, Salvador Mena-Mollá, José Luis García-Giménez
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionSepsis patients experience a complex interplay of host pro- and anti-inflammatory processes which compromise the clinical outcome. Despite considering the latest clinical and scientific research, our comprehension of the immunosuppressive
Externí odkaz:
https://doaj.org/article/067ce3ac24524e78b7477cb2eef62569
Autor:
José Luis García-Giménez, Eva García-López, Salvador Mena-Mollá, Jesús Beltrán-García, Rebeca Osca-Verdegal, Elena Nacher-Sendra, Carmen Aguado-Velasco, Germán Casabó-Vallés, Carlos Romá-Mateo, María Rodriguez-Gimillo, Oreto Antúnez, José Ferreres, Federico V. Pallardó, Nieves Carbonell
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background As leading contributors to worldwide morbidity and mortality, sepsis and septic shock are considered a major global health concern. Proactive biomarker identification in patients with sepsis suspicion at any time remains a dauntin
Externí odkaz:
https://doaj.org/article/76e3c8c2fdd64797b107d621919c802a
Autor:
Rocío García-Arroyo, Elena B. Domènech, Carlos Herrera-Úbeda, Miguel A. Asensi, Cristina Núñez de Arenas, José M. Cuezva, Jordi Garcia-Fernàndez, Federico V. Pallardó, Serena Mirra, Gemma Marfany
Publikováno v:
Redox Biology, Vol 66, Iss , Pp 102862- (2023)
The retina is particularly vulnerable to genetic and environmental alterations that generate oxidative stress and cause cellular damage in photoreceptors and other retinal neurons, eventually leading to cell death. CERKL (CERamide Kinase-Like) mutati
Externí odkaz:
https://doaj.org/article/3956c7ada76a466f93445df60c4c46ff
Autor:
José Luis García-Giménez, Elena R. García-Trevijano, Ana I. Avilés-Alía, José Santiago Ibañez-Cabellos, Miquel Bovea-Marco, Teresa Bas, Federico V. Pallardó, Juan R. Viña, Rosa Zaragozá
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Background Limb-girdle muscular dystrophy (LGMD) is a rare neuromuscular disease including a growing and heterogeneous number of subtypes with variable phenotype. Their clinical and histopathological characteristics frequently overlap with o
Externí odkaz:
https://doaj.org/article/83e53770d7ef42e49a96358ffec61d31
Autor:
Clara Mayayo-Vallverdú, Miguel López de Heredia, Esther Prat, Laura González, Meritxell Espino Guarch, Clara Vilches, Lourdes Muñoz, Miguel A. Asensi, Carmen Serra, Amadeu Llebaria, Mercedes Casado, Rafael Artuch, Gloria Garrabou, Pablo M. Garcia-Roves, Federico V. Pallardó, Virginia Nunes
Publikováno v:
Redox Biology, Vol 64, Iss , Pp 102801- (2023)
The high recurrence rate of cystine lithiasis observed in cystinuria patients highlights the need for new therapeutic options to address this chronic disease. There is growing evidence of an antioxidant defect in cystinuria, which has led to test ant
Externí odkaz:
https://doaj.org/article/af072a2d640d476fa7f993ce82b38f63
Autor:
Rebeca Osca-Verdegal, Jesús Beltrán-García, José Luis Górriz, José María Martínez Jabaloyas, Federico V. Pallardó, José Luis García-Giménez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Renal cell carcinoma is the most common type of kidney cancer, representing 90% of kidney cancer diagnoses, and the deadliest urological cancer. While the incidence and mortality rates by renal cell carcinoma are higher in men compared to women, in b
Externí odkaz:
https://doaj.org/article/3e47ba969e7e4a3abfa54a0ed6067c2a
Autor:
Diana C. Muñoz-Lasso, Belén Mollá, Jhon J. Sáenz-Gamboa, Edwin Insuasty, Maria de la Iglesia-Vaya, Mark A. Pook, Federico V. Pallardó, Francesc Palau, Pilar Gonzalez-Cabo
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Computational techniques for analyzing biological images offer a great potential to enhance our knowledge of the biological processes underlying disorders of the nervous system. Friedreich’s Ataxia (FRDA) is a rare progressive neurodegenerative inh
Externí odkaz:
https://doaj.org/article/fcfaa47a9b894c7b992c0ad1f5f305dc