Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Federico Tinarelli"'
Autor:
Federico Tinarelli, Elena Ivanova, Ilaria Colombi, Erica Barini, Edoardo Balzani, Celina Garcia Garcia, Laura Gasparini, Michela Chiappalone, Gavin Kelsey, Valter Tucci
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-18 (2021)
Abstract Background DNA methylation has emerged as an important epigenetic regulator of brain processes, including circadian rhythms. However, how DNA methylation intervenes between environmental signals, such as light entrainment, and the transcript
Externí odkaz:
https://doaj.org/article/d86afad3f2174d6ea036e7d177eee01c
Autor:
Petrina Lau, Michelle Simon, Anna Hoerder-Suabedissen, Federico Tinarelli, Andrew Rutman, Patrick M. Nolan, Neil R. Horner, Matthew Sweeting, Johanna E. Chesham, Sara Johnson, Henrik Westerberg, Gareth Banks, Ashleigh G. Wilcox, Zoltán Molnár, Alun R. Barnard, Valter Tucci, Robert A. Hirst, Glenda Lassi, Lee B. Smith, Michael H. Hastings, Thomas N. Lawson
Publikováno v:
Molecular Psychiatry
Banks, G, Lassi, G, Hoerder-Suabedissen, A, Tinarelli, F, Simon, M M, Wilcox, A, Lau, P, Lawson, T N, Johnson, S, Rutman, A, Sweeting, M, Chesham, J E, Barnard, A R, Horner, N R, Westerberg, H, Smith, L B, Molnar, Z, Hastings, M H, Hirst, R A, Tucci, V & Nolan, P 2017, ' A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies ', Molecular Psychiatry . https://doi.org/10.1038/mp.2017.54
Banks, G, Lassi, G, Hoerder-Suabedissen, A, Tinarelli, F, Simon, M M, Wilcox, A, Lau, P, Lawson, T N, Johnson, S, Rutman, A, Sweeting, M, Chesham, J E, Barnard, A R, Horner, N R, Westerberg, H, Smith, L B, Molnar, Z, Hastings, M H, Hirst, R A, Tucci, V & Nolan, P 2017, ' A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies ', Molecular Psychiatry . https://doi.org/10.1038/mp.2017.54
Microtubule severing enzymes implement a diverse range of tissue-specific molecular functions throughout development and into adulthood. Although microtubule severing is fundamental to many dynamic neural processes, little is known regarding the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e812ddefabe028080423319d8be25e2
Autor:
Glenda Lassi, Edoardo Balzani, Silvia Maggi, Patrick M. Nolan, Liudmila Mus, Andrea Plano, Valter Tucci, Federico Tinarelli, Raul R. Gainetdinov, Thierry Nieus, Celina Garcia-Garcia, Stefano Espinoza, Fuat Balcı
Publikováno v:
Maggi, S, Balzani, E, Lassi, G, Garcia-Garcia, C, Plano, A, Espinoza, S, Mus, L, Tinarelli, F, Nolan, P M, Gainetdinov, R R, Balci, F, Nieus, T & Tucci, V 2017, ' The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis ', Scientific Reports, vol. 7, no. 1, 17765 . https://doi.org/10.1038/s41598-017-18130-2
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Circadian clock is known to adapt to environmental changes and can significantly influence cognitive and physiological functions. In this work, we report specific behavioral, cognitive, and sleep homeostatic defects in the after hours (Afh) circadian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f746f590ca10063827da2794112cc063
https://doi.org/10.1038/s41598-017-18130-2
https://doi.org/10.1038/s41598-017-18130-2
Autor:
Erica, Barini, Ageo, Miccoli, Federico, Tinarelli, Katie, Mulholland, Hachemi, Kadri, Farhat, Khanim, Laste, Stojanovski, Kevin D, Read, Kerry, Burness, Julian J, Blow, Youcef, Mehellou, Miratul M K, Muqit
Publikováno v:
Chembiochem
Mutations in PINK1, which impair its catalytic kinase activity, are causal for autosomal recessive early‐onset Parkinson's disease (PD). Various studies have indicated that the activation of PINK1 could be a useful strategy in treating neurodegener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43c0e28f6180f669c6e2330c0a690cb0
https://pubmed.ncbi.nlm.nih.gov/29226533
https://pubmed.ncbi.nlm.nih.gov/29226533
Autor:
Federico Tinarelli, Glenda Lassi
Publikováno v:
Handbook of Neurobehavioral Genetics and Phenotyping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53ed9dd57c150c847f7a35f0ad1e6568
https://doi.org/10.1002/9781118540770.ch17
https://doi.org/10.1002/9781118540770.ch17
Publikováno v:
Frontiers in Neuroscience
Reason for Corrigendum: The primer pairs for the gene Homer1 reported in the original manuscript referred to the longer isoforms Homer1b/c and not Homer1a. Moreover, we added some missing references. Therefore at Page 2, Third paragraph, 11th line: t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6b010ae2c5af0681c3542a4db99622
https://doi.org/10.3389/fnins.2016.00409
https://doi.org/10.3389/fnins.2016.00409
Publikováno v:
Frontiers in Neuroscience
In this paper, we show that neuronal assemblies plated on Micro Electrode Arrays present synchronized, low frequency firing patterns similar to in vivo slow wave oscillations, which are a key parameter of sleep-like state. Although neuronal cultures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd9b119d1d3e8a01d8c2e80067077c0
http://europepmc.org/articles/PMC4935686
http://europepmc.org/articles/PMC4935686
Autor:
Marco Pagani, Federico Tinarelli, Alessandro Gozzi, Edoardo Balzani, Silvia Maggi, Alessandro Mauro, Valter Tucci, Graziano Grugni, Daniela Giardino, Jo Peters, Nadia El-Assawy, Lorenzo Priano, Celina Garcia-Garcia, Glenda Lassi
Study objectives Sleep-wake disturbances are often reported in Prader-Willi syndrome (PWS), a rare neurodevelopmental syndrome that is associated with paternally-expressed genomic imprinting defects within the human chromosome region 15q11-13. One of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94bf729ec0f434fe1fb4f70ca436c57d
https://europepmc.org/articles/PMC4763347/
https://europepmc.org/articles/PMC4763347/
Autor:
Thierry Nieus, Silvia Maggi, Patrick M. Nolan, Michelle Simon, Luca Dodero, Daniela Cantatore, Laura Gasparini, Willy N. Nillesen, Christopher T. Esapa, Lisenka E. L. M. Vissers, Sotirios A. Tsaftaris, Helen Hilton, Zafar Iqbal, Andrea Hardy, Sara Wells, Ines Heise, Marlies J. Kempers, Andrea Raimondi, Valter Tucci, MH Willemsen, Alessandro Gozzi, Marta Orlando, Glenda Lassi, Alessandro Maccione, Pasqualina Farisello, Federico Tinarelli, Tjitske Kleefstra, Liam J. McGuffin, Luca Berdondini, Rosario Romero, Angelo Bifone, Andrea Contestabile, Maria T. Buenavista, Barbara Greco, Anneke T. Vulto-van Silfhout, Lucie Vizor
Publikováno v:
Journal of Clinical Investigation, 124, 4, pp. 1468-82
Journal of Clinical Investigation, 124, 1468-82
Journal of Clinical Investigation, 124, 1468-82
Contains fulltext : 137817.pdf (Publisher’s version ) (Open Access) The recent identification of multiple dominant mutations in the gene encoding beta-catenin in both humans and mice has enabled exploration of the molecular and cellular basis of be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacb2576bf221c10c1a7b203bb7ca8d2
https://europepmc.org/articles/PMC3973091/
https://europepmc.org/articles/PMC3973091/
Sleep homoeostasis refers to a process in which the propensity to sleep increases as wakefulness progresses and decreases as sleep progresses. Sleep is tightly organized around the circadian clock and is regulated by genetic and epigenetic mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60cd6762692b2d842b8f46f685e37c9
https://europepmc.org/articles/PMC3895995/
https://europepmc.org/articles/PMC3895995/