Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Federico Serral"'
1
Akademický článek
Five-year microevolution of a multidrug-resistant Mycobacterium tuberculosis strain within a patient with inadequate compliance to treatment
Autor: Darío A. Fernandez Do Porto, Johana Monteserin, Josefina Campos, Ezequiel J. Sosa, Mario Matteo, Federico Serral, Noemí Yokobori, Andrés Fernández Benevento, Tomás Poklepovich, Agustín Pardo, Ingrid Wainmayer, Norberto Simboli, Florencia Castello, Roxana Paul, Marcelo Martí, Beatriz López, Adrián Turjanski, Viviana Ritacco
Publikováno v: BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Whole-genome sequencing has shown that the Mycobacterium tuberculosis infection process can be more heterogeneous than previously thought. Compartmentalized infections, exogenous reinfections, and microevolution are manifestations
Externí odkaz: https://doaj.org/article/d76470240d6c495a8ec9c6c917849960
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2
Akademický článek
Pathway Driven Target Selection in Klebsiella pneumoniae: Insights Into Carbapenem Exposure
Autor: Federico Serral, Agustin M. Pardo, Ezequiel Sosa, María Mercedes Palomino, Marisa F. Nicolás, Adrian G. Turjanski, Pablo Ivan P. Ramos, Darío Fernández Do Porto
Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Carbapenem-resistant Klebsiella pneumoniae (CR-KP) represents an emerging threat to public health. CR-KP infections result in elevated morbidity and mortality. This fact, coupled with their global dissemination and increasingly limited number of ther
Externí odkaz: https://doaj.org/article/f32860b135a5461d86e242de8452f118
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3
Akademický článek
From Genome to Drugs: New Approaches in Antimicrobial Discovery
Autor: Federico Serral, Florencia A. Castello, Ezequiel J. Sosa, Agustín M. Pardo, Miranda Clara Palumbo, Carlos Modenutti, María Mercedes Palomino, Alberto Lazarowski, Jerónimo Auzmendi, Pablo Ivan P. Ramos, Marisa F. Nicolás, Adrián G. Turjanski, Marcelo A. Martí, Darío Fernández Do Porto
Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)
Decades of successful use of antibiotics is currently challenged by the emergence of increasingly resistant bacterial strains. Novel drugs are urgently required but, in a scenario where private investment in the development of new antimicrobials is d
Externí odkaz: https://doaj.org/article/1652ee5980544316aeef52a46431288e
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4
Akademický článek
Prioritisation of potential drug targets against Bartonella bacilliformis by an integrative in-silico approach
Autor: Mariella Farfán-López, Abraham Espinoza-Culupú, Ruth García-de-la-Guarda, Federico Serral, Ezequiel Sosa, María Mercedes Palomino, Darío A Fernández Do Porto
Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 115 (2020)
BACKGROUND Carrion’s disease (CD) is a neglected biphasic illness caused by Bartonella bacilliformis, a Gram-negative bacteria found in the Andean valleys. The spread of resistant strains underlines the need for novel antimicrobials against B. baci
Externí odkaz: https://doaj.org/article/8d3f389cb772479f8617b70f179ecf06
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5
Akademický článek
Methylobacterium sp. 2A Is a Plant Growth-Promoting Rhizobacteria That Has the Potential to Improve Potato Crop Yield Under Adverse Conditions
Autor: Cecilia Eugenia María Grossi, Elisa Fantino, Federico Serral, Myriam Sara Zawoznik, Darío Augusto Fernandez Do Porto, Rita María Ulloa
Publikováno v: Frontiers in Plant Science, Vol 11 (2020)
A Gram-negative pink-pigmented bacillus (named 2A) was isolated from Solanum tuberosum L. cv. Desirée plants that were strikingly more developed, presented increased root hair density, and higher biomass than other potato lines of the same age. The
Externí odkaz: https://doaj.org/article/a0c112928fdb413abb4759ef181f6ecb
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6
Akademický článek
Identification of Potential Kinase Inhibitors within the PI3K/AKT Pathway of Leishmania Species
Autor: Rodrigo Ochoa, Amaya Ortega-Pajares, Florencia A. Castello, Federico Serral, Darío Fernández Do Porto, Janny A. Villa-Pulgarin, Rubén E. Varela-M, Carlos Muskus
Publikováno v: Biomolecules, Vol 11, Iss 7, p 1037 (2021)
Leishmaniasis is a public health disease that requires the development of more effective treatments and the identification of novel molecular targets. Since blocking the PI3K/AKT pathway has been successfully studied as an effective anticancer strate
Externí odkaz: https://doaj.org/article/d8b62333c2da49bfb36bbea6ccf1300b
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7
Integrating diverse layers of omic data to identify novel drug targets in Listeria monocytogenes
Autor: Miranda Palumbo, Ezequiel Sosa, Florencia Castello, Gustavo Schottlender, Federico Serral, Adrián Turjanski, María Mercedes Palomino, Darío Fernández Do Porto
Publikováno v: Frontiers in Drug Discovery. 2
Listeriamonocytogenes (Lm) is a Gram-positive bacillus responsible for listeriosis in humans. Listeriosis has become a major foodborne illness in recent years. This illness is mainly associated with the consumption of contaminated food and ready-to-e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c10ce4d651d4b929f0e4d427d47aa673
https://doi.org/10.3389/fddsv.2022.969415
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9
Five-year microevolution of a multidrug-resistant Mycobacterium tuberculosis strain within a patient with inadequate compliance to treatment
Autor: Norberto Simboli, Johana Monteserin, Tomás Poklepovich, Agustin Maria Pardo, Darío Fernández Do Porto, Ingrid Wainmayer, Andres Fernandez Benevento, Josefina Campos, Federico Serral, Marcelo A. Martí, Viviana Ritacco, Noemí Yokobori, Mario José Matteo, Florencia Andrea Castello, Beatriz López, Ezequiel Sosa, Adrian Turjanski, Roxana Paul
Publikováno v: BMC Infectious Diseases
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-10 (2021)
Background Whole-genome sequencing has shown that the Mycobacterium tuberculosis infection process can be more heterogeneous than previously thought. Compartmentalized infections, exogenous reinfections, and microevolution are manifestations of this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789f5a16602ce478c6de189c74c8f98d
https://doi.org/10.1186/s12879-021-06069-9
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10
Prioritisation of potential drug targets against Bartonella bacilliformis by an integrative in-silico approach
Autor: Darío Fernández Do Porto, Mariella Farfán-López, Maria Mercedes Palomino, Ezequiel Sosa, Abraham Espinoza-Culupú, Ruth García-de-la-Guarda, Federico Serral
Publikováno v: Memórias do Instituto Oswaldo Cruz., Vol 115 (2020)
Memórias do Instituto Oswaldo Cruz
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
BACKGROUND Carrion’s disease (CD) is a neglected biphasic illness caused by Bartonella bacilliformis, a Gram-negative bacteria found in the Andean valleys. The spread of resistant strains underlines the need for novel antimicrobials against B. baci
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a866d2ef4a80325d579af24b41d6badb
http://www.scielo.br/pdf/mioc/v115/1678-8060-mioc-115-e200184.pdf
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