Sarcopenia evaluated by EASL/AASLD computed tomography-based criteria predicts mortality in patients with cirrhosis: A systematic review and meta-analysis

Autor: Elton Dajti, Susana G. Rodrigues, Federica Perazza, Luigi Colecchia, Giovanni Marasco, Matteo Renzulli, Giovanni Barbara, Francesco Azzaroli, Annalisa Berzigotti, Antonio Colecchia, Federico Ravaioli

Publikováno v: JHEP Reports, Vol 6, Iss 8, Pp 101113- (2024)

Background & Aims: Sarcopenia is associated with increased morbidity and mortality in patients with cirrhosis, but its definition in current literature is very heterogeneous. We performed a systematic review and meta-analysis to assess the associatio

Externí odkaz: https://doaj.org/article/c891382aec4843878537ce8e736a8f05

Metformin and the Liver: Unlocking the Full Therapeutic Potential

Autor: Federica Perazza, Laura Leoni, Santo Colosimo, Alessandra Musio, Giulia Bocedi, Michela D’Avino, Giulio Agnelli, Alba Nicastri, Chiara Rossetti, Federica Sacilotto, Giulio Marchesini, Maria Letizia Petroni, Federico Ravaioli

Publikováno v: Metabolites, Vol 14, Iss 4, p 186 (2024)

Metformin is a highly effective medication for managing type 2 diabetes mellitus. Recent studies have shown that it has significant therapeutic benefits in various organ systems, particularly the liver. Although the effects of metformin on metabolic

Externí odkaz: https://doaj.org/article/1e23f0dfb91c443c91d74ccccb84b803

Landscape of alcohol-related hepatocellular carcinoma in the last 15 years highlights the need to expand surveillance programs

Autor: Nicola Reggidori, Laura Bucci, Valentina Santi, Benedetta Stefanini, Lorenzo Lani, Davide Rampoldi, Giorgia Ghittoni, Fabio Farinati, Alberto Masotto, Bernardo Stefanini, Andrea Mega, Elisabetta Biasini, Francesco Giuseppe Foschi, Gianluca Svegliati-Baroni, Angelo Sangiovanni, Claudia Campani, Giovanni Raimondo, Gianpaolo Vidili, Antonio Gasbarrini, Ciro Celsa, Mariella Di Marco, Edoardo G. Giannini, Rodolfo Sacco, Maurizia Rossana Brunetto, Francesco Azzaroli, Donatella Magalotti, Filomena Morisco, Gian Ludovico Rapaccini, Gerardo Nardone, Alessandro Vitale, Franco Trevisani, Maurizio Biselli, Paolo Caraceni, Annagiulia Gramenzi, Francesca Benevento, Alessandro Granito, Luca Muratori, Fabio Piscaglia, Francesco Tovoli, Gloria Allegrini, Calogero Cammà, Giuseppe Cabibbo, Carmelo Marco Giacchetto, Paolo Giuffrida, Maria Vittoria Grassini, Mauro Grova, Gabriele Rancatore, Caterina Stornello, Valentina Adotti, Tancredi Li Cavoli, Fabio Marra, Martina Rosi, Vittoria Bevilacqua, Alberto Borghi, Lucia Napoli, Fabio Conti, G.L. Frassineti, Maria Teresa Migliano, Nicoletta de Matthaeis, Francesca Romana Ponziani, Gabriele Missale, Andrea Olivani, Mario Capasso, Valentina Cossiga, Maria Guarino, Ester Marina Cela, Antonio Facciorusso, Camilla Graziosi, Valentina Lauria, Giorgio Pelecca, Marta Schirripa, Fabrizio Chegai, Armando Raso, Alessio Bozzi, Maria Stella Franzè, Carlo Saitta, Assunta Sauchella, Elton Dajti, Federico Ravaioli, Maria Corina Plaz Torres, Giulia Pieri, Filippo Oliveri, Gabriele Ricco, Veronica Romagnoli, Alessandro Inno, Fabiana Marchetti, Pietro Coccoli, Antonio Malerba, Alberta Cappelli, Rita Golfieri, Cristina Mosconi, Matteo Renzulli

Publikováno v: JHEP Reports, Vol 5, Iss 8, Pp 100784- (2023)

Background & Aims: Alcohol abuse and metabolic disorders are leading causes of hepatocellular carcinoma (HCC) worldwide. Alcohol-related aetiology is associated with a worse prognosis compared with viral agents, because of the lower percentage of pat

Externí odkaz: https://doaj.org/article/994809fcb7eb4d6c91173f05293807e2

Endothelial angiopoietin-2 overexpression in explanted livers identifies subjects at higher risk of recurrence of hepatocellular carcinoma after liver transplantation

Autor: Simone Lasagni, Filippo Leonardi, Alessandra Pivetti, Lorenza Di Marco, Federico Ravaioli, Matteo Serenari, Stefano Gitto, Rosina Maria Critelli, Fabiola Milosa, Adriana Romanzi, Serena Mancarella, Francesco Dituri, Mattia Riefolo, Barbara Catellani, Paolo Magistri, Dante Romagnoli, Ciro Celsa, Marco Enea, Nicola de Maria, Filippo Schepis, Antonio Colecchia, Calogero Cammà, Matteo Cescon, Antonietta d’Errico, Fabrizio di Benedetto, Gianluigi Giannelli, Maria Luz Martinez-Chantar, Erica Villa

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

BackgroundThough the precise criteria for accessing LT are consistently being applied, HCC recurrence (HCC-R_LT) still affects more than 15% of the patients. We analyzed the clinical, histopathological, and biological features of patients with HCC to

Externí odkaz: https://doaj.org/article/04fffa84d0da483480db0b505887750f

From Listing to Recovery: A Review of Nutritional Status Assessment and Management in Liver Transplant Patients

Autor: Federico Ravaioli, Nicola De Maria, Lorenza Di Marco, Alessandra Pivetti, Riccardo Casciola, Carlo Ceraso, Gabriella Frassanito, Martina Pambianco, Maddalena Pecchini, Chiara Sicuro, Laura Leoni, Stefano Di Sandro, Paolo Magistri, Renata Menozzi, Fabrizio Di Benedetto, Antonio Colecchia

Publikováno v: Nutrients, Vol 15, Iss 12, p 2778 (2023)

Liver transplantation (LT) is a complex surgical procedure requiring thorough pre- and post-operative planning and care. The nutritional status of the patient before, during, and after LT is crucial to surgical success and long-term prognosis. This r

Externí odkaz: https://doaj.org/article/a299ccb2917c4bcdb307bacaa073d903