Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Federico N. Penas"'
Autor:
Azul V. Pieralisi, Ágata C. Cevey, Federico N. Penas, Nilda Prado, Ana Mori, Mónica Gili, Gerardo A. Mirkin, Juan Gagliardi, Nora B. Goren
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Chronic Chagas disease cardiomyopathy (CCC) is the most important clinical manifestation of infection with Trypanosma cruzi (T. cruzi) due to its frequency and effects on morbidity and mortality. Peripheral blood mononuclear cells (PBMC) infiltrate t
Externí odkaz:
https://doaj.org/article/b37c26a35ff94c1c822003ac05280bdf
Autor:
Ágata C. Cevey, Paula D. Mascolo, Federico N. Penas, Azul V. Pieralisi, Aldana S. Sequeyra, Gerardo A. Mirkin, Nora B. Goren
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Benznidazole (Bzl), the drug of choice in many countries for the treatment of Chagas disease, leads to parasite clearance in the early stages of infection and contributes to immunomodulation. In addition to its parasiticidal effect, Bzl inhibits the
Externí odkaz:
https://doaj.org/article/a448a705e0d847578212886c8a173008
Autor:
Jimena Rada, Martín Donato, Federico N. Penas, Catalina Alba Soto, Ágata C. Cevey, Azul V. Pieralisi, Ricardo Gelpi, Gerardo A. Mirkin, Nora B. Goren
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IL-10 is an anti-inflammatory cytokine that plays a significant role in the modulation of the immune response in many pathological conditions, including infectious diseases. Infection with Trypanosoma cruzi (T. cruzi), the etiological agent of Chagas
Externí odkaz:
https://doaj.org/article/789a7dcbe9e04d4498aac08b8da6b2f8
Autor:
Ágata C. Cevey, Gerardo A. Mirkin, Martín Donato, María J. Rada, Federico N. Penas, Ricardo J. Gelpi, Nora B. Goren
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 7, Iss 3, Pp 378-387 (2017)
Trypanosoma cruzi induces serious cardiac alterations during the chronic infection. Intense inflammatory response observed from the beginning of infection, is critical for the control of parasite proliferation and evolution of Chagas disease. Peroxis
Externí odkaz:
https://doaj.org/article/2098241fed4f460e822eb3c21cc598c1
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Anti-parasitic treatment for Chagas disease mainly relies on benznidazole, which is virtually the only drug available in the market. Besides its anti-parasitic effects, benznidazole has anti-inflammatory properties. In this work we studied the mechan
Externí odkaz:
https://doaj.org/article/5b549f72290a47658f292520769d03de
Autor:
Cristina S. Rigazio, Nilo Mariz-Ponte, Eugenia Pérez Caballero, Federico N. Penas, Nora B. Goren, Miguel H. Santamaría, Ricardo S. Corral
Publikováno v:
Microbial pathogenesis. 173
Cardiomyopathy is the most serious complication of chronic Chagas disease, caused by infection with the protozoan Trypanosoma cruzi. Exacerbated inflammation of the myocardium constitutes a major pathologic component of the disease. In the myocardial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b53d285ca9aad660c492ab53b25cafd
https://pubmed.ncbi.nlm.nih.gov/36379373
https://pubmed.ncbi.nlm.nih.gov/36379373