Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Federico Munafò"'
Autor:
Patrizia Sarogni, Nicoletta Brindani, Agata Zamborlin, Alessandra Gonnelli, Michele Menicagli, Ana Katrina Mapanao, Federico Munafò, Marco De Vivo, Valerio Voliani
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Oral malignancies continue to have severe morbidity with less than 50% long-term survival despite the advancement in the available therapies. There is a persisting demand for new approaches to establish more efficient strategies for their tr
Externí odkaz:
https://doaj.org/article/c10e6e954fdd4079a96c1211bb80dcb5
Autor:
Federico Munafò, Elisa Donati, Nicoletta Brindani, Giuliana Ottonello, Andrea Armirotti, Marco De Vivo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a global health pandemic. Among the viral proteins, RNA-dependent RNA polymerase (RdRp) is responsible for viral genome replication and has emerged as one of the
Externí odkaz:
https://doaj.org/article/2c3f783d4fc748caa1324575af084868
Autor:
Federico Munafò, Michela Nigro, Nicoletta Brindani, Jacopo Manigrasso, Inacrist Geronimo, Giuliana Ottonello, Andrea Armirotti, Marco De Vivo
Publikováno v:
SSRN Electronic Journal.
In cancer cells, Pol η allows DNA replication and cell proliferation even in the presence of chemotherapeutic drug-induced damages, like in the case of platinum-containing drugs. Inhibition of Pol η thus represents a promising strategy to overcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49ed3386c1e5ef4a00996f70c30d1b3
https://doi.org/10.2139/ssrn.4200126
https://doi.org/10.2139/ssrn.4200126
Autor:
Nicoletta Brindani, Federico Munafò, Andrea Menichetti, Elisa Donati, Michela Nigro, Giuliana Ottonello, Andrea Armirotti, Marco De Vivo
Publikováno v:
Bioorganic & Medicinal Chemistry. 80:117179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1302065b501be78fa5ab41d7db466a0
https://doi.org/10.1016/j.bmc.2023.117179
https://doi.org/10.1016/j.bmc.2023.117179
Autor:
Federico Munafò, Elisa Donati, Nicoletta Brindani, Giuliana Ottonello, Andrea Armirotti, Marco De Vivo
Publikováno v:
Scientific reports. 12(1)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a global health pandemic. Among the viral proteins, RNA-dependent RNA polymerase (RdRp) is responsible for viral genome replication and has emerged as one of the most pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab404176077c1438d846288160a23ccf
https://pubmed.ncbi.nlm.nih.gov/35732785
https://pubmed.ncbi.nlm.nih.gov/35732785
Autor:
Anthony D. Garcia, Kim T. Tran, Lars Jakobsen Høj, Jakob S. Pallesen, Tommy N. Johansen, Giuseppe Marseglia, Michael Gajhede, Federico Munafò, Michael Sattler, Grzegorz M Popowicz, Haritha L. Desu, Dilip Narayanan, Sara Marie Øie Solbak, Anders Bach, Louis M.E. Sørensen, Rosa M. C. Carmona, Roberta Brambilla
Publikováno v:
Pallesen, J S, Narayanan, D, Tran, K T, Solbak, S M Ø, Marseglia, G, Sørensen, L M E, Høj, L J, Munafò, F, Carmona, R M C, Garcia, A D, Desu, H L, Brambilla, R, Johansen, T N, Popowicz, G M, Sattler, M, Gajhede, M & Bach, A 2021, ' Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds ', Journal of Medicinal Chemistry, vol. 64, no. 8, pp. 4623-4661 . https://doi.org/10.1021/acs.jmedchem.0c02094
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (8), pp.4623-4661. ⟨10.1021/acs.jmedchem.0c02094⟩
J. Med. Chem. 64, 4623-4661 (2021)
Journal of Medicinal Chemistry, 2021, 64 (8), pp.4623-4661. ⟨10.1021/acs.jmedchem.0c02094⟩
Pallesen, J S, Narayanan, D, Tran, K T, Solbak, S M Ø, Marseglia, G, Sørensen, L M E, Høj, L J, Munafò, F, Carmona, R M C, Garcia, A D, Desu, H L, Brambilla, R, Johansen, T N, Popowicz, G M, Sattler, M, Gajhede, M & Bach, A 2021, ' Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds ', Journal of Medicinal Chemistry, vol. 64, no. 8, pp. 4623–4661 . https://doi.org/10.1021/acs.jmedchem.0c02094
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (8), pp.4623-4661. ⟨10.1021/acs.jmedchem.0c02094⟩
J. Med. Chem. 64, 4623-4661 (2021)
Journal of Medicinal Chemistry, 2021, 64 (8), pp.4623-4661. ⟨10.1021/acs.jmedchem.0c02094⟩
Pallesen, J S, Narayanan, D, Tran, K T, Solbak, S M Ø, Marseglia, G, Sørensen, L M E, Høj, L J, Munafò, F, Carmona, R M C, Garcia, A D, Desu, H L, Brambilla, R, Johansen, T N, Popowicz, G M, Sattler, M, Gajhede, M & Bach, A 2021, ' Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds ', Journal of Medicinal Chemistry, vol. 64, no. 8, pp. 4623–4661 . https://doi.org/10.1021/acs.jmedchem.0c02094
Targeting the protein–protein interaction (PPI) between nuclear factor erythroid 2-related factor 2 (Nrf2) and Kelch-like ECH-associated protein 1 (Keap1) is a potential therapeutic strategy to control diseases involving oxidative stress. Here, six
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be38b6b6fe59378aedc77f3f260f9ff0
https://pubmed.ncbi.nlm.nih.gov/33818106
https://pubmed.ncbi.nlm.nih.gov/33818106