Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Federico Morán"'
Autor:
Soledad Delgado, Celia Perales, Carlos García-Crespo, María Eugenia Soria, Isabel Gallego, Ana Isabel de Ávila, Brenda Martínez-González, Lucía Vázquez-Sirvent, Cecilio López-Galíndez, Federico Morán, Esteban Domingo
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT RNA viruses replicate as complex mutant spectra termed viral quasispecies. The frequency of each individual genome in a mutant spectrum depends on its rate of generation and its relative fitness in the replicating population ensemble. The ad
Externí odkaz:
https://doaj.org/article/041d5980a232449789212264732757dd
Autor:
Brenda Martínez-González, María Eugenia Soria, Lucía Vázquez-Sirvent, Cristina Ferrer-Orta, Rebeca Lobo-Vega, Pablo Mínguez, Lorena de la Fuente, Carlos Llorens, Beatriz Soriano, Ricardo Ramos-Ruíz, Marta Cortón, Rosario López-Rodríguez, Carlos García-Crespo, Pilar Somovilla, Antoni Durán-Pastor, Isabel Gallego, Ana Isabel de Ávila, Soledad Delgado, Federico Morán, Cecilio López-Galíndez, Jordi Gómez, Luis Enjuanes, Llanos Salar-Vidal, Mario Esteban-Muñoz, Jaime Esteban, Ricardo Fernández-Roblas, Ignacio Gadea, Carmen Ayuso, Javier Ruíz-Hornillos, Nuria Verdaguer, Esteban Domingo, Celia Perales
Publikováno v:
Pathogens, Vol 11, Iss 6, p 662 (2022)
Populations of RNA viruses are composed of complex and dynamic mixtures of variant genomes that are termed mutant spectra or mutant clouds. This applies also to SARS-CoV-2, and mutations that are detected at low frequency in an infected individual ca
Externí odkaz:
https://doaj.org/article/1a2a6aef651b4189a3f7cf754f253bd4
Autor:
Gabriel Piedrafita, Francisco Montero, Federico Morán, María Luz Cárdenas, Athel Cornish-Bowden
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 8, Pp 861-864 (2010)
A living organism must not only organize itself from within; it must also maintain its organization in the face of changes in its environment and degradation of its components. We show here that a simple (M,R)-system consisting of three interlocking
Externí odkaz:
https://doaj.org/article/526ee2225122426db75ace3ec68bf75d
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88579 (2014)
Human Immunodeficiency Virus type 1 (HIV-1) because of high mutation rates, large population sizes, and rapid replication, exhibits complex evolutionary strategies. For the analysis of evolutionary processes, the graphical representation of fitness l
Externí odkaz:
https://doaj.org/article/6a2ed8afb4a841e8b4de71a78d165cf0
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96732 (2014)
The prediction of links among variables from a given dataset is a task referred to as network inference or reverse engineering. It is an open problem in bioinformatics and systems biology, as well as in other areas of science. Information theory, whi
Externí odkaz:
https://doaj.org/article/546421c7ce6b4544a85a2e1201229ec0
Publikováno v:
PLoS ONE, Vol 7, Iss 11 (2012)
Externí odkaz:
https://doaj.org/article/5c6441ce438b4753845b37dc98b2e7cf
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41122 (2012)
Determining the regulation of metabolic networks at genome scale is a hard task. It has been hypothesized that biochemical pathways and metabolic networks might have undergone an evolutionary process of optimization with respect to several criteria o
Externí odkaz:
https://doaj.org/article/bb780e66868d45eea6dfca089ac660aa
Autor:
Tapia, Fernando Elgueta, Iturri, Goizalde Solano, Macias, Alfonso Gutiérrez, Bocero, Marta Copado, Cuesta, Federico Moran
Publikováno v:
In Revista clinica espanola November 2023 223 Supplement 2:S629-S631
Autor:
Carlos García-Crespo, Federico Morán, Soledad Delgado, Cecilio López-Galíndez, Brenda Martínez-González, Celia Perales, Lucía Vázquez-Sirvent, María Eugenia Soria, Ana Isabel de Ávila, Esteban Domingo, Isabel Gallego
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
Microbiology Spectrum
Microbiology Spectrum
RNA viruses replicate as complex mutant spectra termed viral quasispecies. The frequency of each individual genome in a mutant spectrum depends on its rate of generation and its relative fitness in the replicating population ensemble. The advent of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78759852fcb4f834c64133826da134ae
https://journals.asm.org/doi/10.1128/Spectrum.01459-21
https://journals.asm.org/doi/10.1128/Spectrum.01459-21
Autor:
Isabel Gallego, Brenda Martínez-González, de Ávila Ai, Celia Perales, Federico Morán, Soledad Delgado, Lucía Vázquez-Sirvent, Esteban Domingo, María Eugenia Soria, Cecilio López-Galíndez, Carlos García-Crespo
Fitness landscapes reflect the adaptive potential of viruses. There is no information on how fitness peaks evolve when a virus replicates extensively in a controlled cell culture environment. Here we report the construction of Self-Organized Maps (SO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c512fcf7bd0bbb7007c2179aa02ffc1c
https://doi.org/10.1101/2021.04.22.441053
https://doi.org/10.1101/2021.04.22.441053
