Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Federico Mauri"'
Autor:
Venu Thatikonda, Verena Supper, Johannes Wachter, Onur Kaya, Anju Kombara, Ceren Bilgilier, Madhwesh C. Ravichandran, Jesse J. Lipp, Rahul Sharma, Lukas Badertscher, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Sarah Grosche, Ralph A. Neumüller, Barbara Mair, Federico Mauri, Alexandra Popa
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114175- (2024)
Summary: Transcription factors (TFs) are important mediators of aberrant transcriptional programs in cancer cells. In this study, we focus on TF activity (TFa) as a biomarker for cell-line-selective anti-proliferative effects, in that high TFa predic
Externí odkaz:
https://doaj.org/article/cf2194b70a344373b2d1a869bceef1a4
Autor:
Federico Mauri, Cédric Blanpain
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 11, Pp n/a-n/a (2020)
Merkel cell carcinoma (MCC) is a rare but very aggressive neuroendocrine cancer of the skin, with very limited therapeutic options. Although immunotherapy is effective in some cases, there is an unmet need for new therapeutic approaches in MCCs. In t
Externí odkaz:
https://doaj.org/article/8ecbaa5cafb44c9f96686769531bf3d4
Autor:
Venu Thatikonda, Verena Supper, Madhwesh C. Ravichandran, Jesse J. Lipp, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Sara Grosche, Ralph A. Neumüller, Barbara Mair, Federico Mauri, Alexandra Popa
Transcription factors (TFs) are key components of the aberrant transcriptional programs in cancer cells. In this study, we used TF activity (TFa), inferred from the downstream regulons as a potential biomarker to identify associated genetic vulnerabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49167a733aa3def504d91a1b261f0825
https://doi.org/10.1101/2023.02.23.529701
https://doi.org/10.1101/2023.02.23.529701
Autor:
Françoise Helmbacher, Jose Jf Millan-Cayetano, Ievgenia Pastushenko, L. Ríos-Buceta, Benjamin Swedlund, Alicia Perez-Bustillo, Magdalena De Troya, Delphi Van Haver, Sergio Hassid, Francis Impens, Bob Meeusen, Sophie Lemaire, Yura Song, Christine Decaestecker, Gaëlle Lapouge, Ramon Sieira-Gil, Cédric Balsat, David Perez-Morga, Beatriz Agreda-Moreno, Cédric Blanpain, Pedro Redondo, Matthieu Opitz, Youri Sokolow, Isabelle Salmon, Christos Sotiriou, Onofre Sanmatrtin, Frédérique De Cock, Virginie Moers, Samuel Scozzaro, Marjorie Vermeersch, Pedro Jaén, Yacine Bareche, Christine Dubois, Milena Rozzi, Nicky D'Haene, Manuel Théry, Yves-Remi Van Eycke, Jeremy Blondeau, Veerle Janssens, Federico Mauri
Publikováno v:
Nature
Nature, 2021, 589 (7842), pp.448-455. ⟨10.1038/s41586-020-03046-1⟩
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Nature, Nature Publishing Group, 2021, 589 (7842), pp.448-455. ⟨10.1038/s41586-020-03046-1⟩
Nature (London)
Nature, 2021, 589 (7842), pp.448-455. ⟨10.1038/s41586-020-03046-1⟩
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Nature, Nature Publishing Group, 2021, 589 (7842), pp.448-455. ⟨10.1038/s41586-020-03046-1⟩
Nature (London)
FAT1, which encodes a protocadherin, is one of the most frequently mutated genes in human cancers1-5. However, the role and the molecular mechanisms by which FAT1 mutations control tumour initiation and progression are poorly understood. Here, using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a0821ba2cc4fea1337e71af62e1782
http://zaguan.unizar.es/record/102099
http://zaguan.unizar.es/record/102099
Autor:
Cédric Blanpain, Federico Mauri
Publikováno v:
EMBO molecular medicine
EMBO Molecular Medicine, Vol 12, Iss 11, Pp n/a-n/a (2020)
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 11, Pp n/a-n/a (2020)
EMBO Molecular Medicine
Merkel cell carcinoma (MCC) is a rare but very aggressive neuroendocrine cancer of the skin, with very limited therapeutic options. Although immunotherapy is effective in some cases, there is an unmet need for new therapeutic approaches in MCCs. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178db74f659a9dc75fb98f342d1c4583
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/314327
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/314327
Autor:
Federico Mauri, Ilka Reichardt, Jennifer Jl Mummery-Widmer, Masakazu Yamazaki, Juergen Ja Knoblich
Publikováno v:
Current Biology
Summary Background Asymmetric cell division (ACD) is a key process that allows different cell types to be generated at precisely defined times and positions. In Drosophila , neural precursor cells rely heavily on ACD to generate the different cell ty
Publikováno v:
Production Planning & Control. 21:695-717
The methodology of continuous improvement in manufacturing is a well-known practice originated by the ‘Japanese approach’ to industrial production. However, some needs still exist for an easy implementation of the improvement procedures it involv
Autor:
Giannino Del Sal, Laura Lm McNamee, Fulvio Chiacchiera, Andrea Lunardi, Licio Collavin, Michael Mh Brodsky, Federico Mauri
Publikováno v:
The Journal of biological chemistry, 283 (30
Conjugation to SUMO is a reversible post-translational modification that regulates several transcription factors involved in cell proliferation, differentiation, and disease. The p53 tumor suppressor can be modified by SUMO-1 in mammalian cells, but
Autor:
Thomas Stoeger, Masakazu Yamazaki, Jennifer L. Mummery-Widmer, Juergen A. Knoblich, Federico Mauri
Publikováno v:
Mechanisms of Development. 126
Autor:
Cédric Blanpain, Marie Miglianico, Isabelle Salmon, Erwin Nkusi, Federico Mauri, Sandrine Rorive, Christos Sotiriou, Justine Allard, Jeremy Blondeau, Christine Dubois, Yacine Bareche, Milena Rozzi, Gaëlle Lapouge, Benoit Durdu, Audrey Brisebarre, Jalal Vakili, Corentin Schepkens, Ievgenia Pastushenko, Sophie Golstein, Maylis Raphaël, Floriane Ribeiro, Virginie Moers, Yura Song, Benjamin Drogat
Publikováno v:
Nature Cancer
The nongenetic mechanisms required to sustain malignant tumor state are poorly understood. During the transition from benign tumors to malignant carcinoma, tumor cells need to repress differentiation and acquire invasive features. Using transcription