Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Federico M Giorgi"'
Autor:
Jayne E. Murray, Emanuele Valli, Giorgio Milazzo, Chelsea Mayoh, Andrew J. Gifford, Jamie I. Fletcher, Chengyuan Xue, Nisitha Jayatilleke, Firoozeh Salehzadeh, Laura D. Gamble, Jourdin R. C. Rouaen, Daniel R. Carter, Helen Forgham, Eric O. Sekyere, Joanna Keating, Georgina Eden, Sophie Allan, Stephanie Alfred, Frances K. Kusuma, Ashleigh Clark, Hannah Webber, Amanda J. Russell, Antoine de Weck, Benjamin T. Kile, Martina Santulli, Piergiuseppe De Rosa, Emmy D. G. Fleuren, Weiman Gao, Lorna Wilkinson-White, Jason K. K. Low, Joel P. Mackay, Glenn M. Marshall, Douglas J. Hilton, Federico M. Giorgi, Jan Koster, Giovanni Perini, Michelle Haber, Murray D. Norris
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract MYCN oncogene amplification is frequently observed in aggressive childhood neuroblastoma. Using an unbiased large-scale mutagenesis screen in neuroblastoma-prone transgenic mice, we identify a single germline point mutation in the transcript
Externí odkaz:
https://doaj.org/article/ee532e0c05a8415d9de099a04d9f475c
Autor:
Maria Stella de Biase, Florian Massip, Tzu-Ting Wei, Federico M. Giorgi, Rory Stark, Amanda Stone, Amy Gladwell, Martin O’Reilly, Daniel Schütte, Ines de Santiago, Kerstin B. Meyer, Florian Markowetz, Bruce A. J. Ponder, Robert C. Rintoul, Roland F. Schwarz
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background Lung cancer is the leading cause of cancer-related death in the world. In contrast to many other cancers, a direct connection to modifiable lifestyle risk in the form of tobacco smoke has long been established. More than 50% of al
Externí odkaz:
https://doaj.org/article/1477c061531644cca19787d9aa30b28b
Autor:
Federico M Giorgi, Gonzalo Lopez, Jung H Woo, Brygida Bisikirska, Andrea Califano, Mukesh Bansal
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163402 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0109569.].
Externí odkaz:
https://doaj.org/article/dc6663b6fe69491bbd3d1277593635d0
Autor:
Nicola Balboni, Giorgia Babini, Eleonora Poeta, Michele Protti, Laura Mercolini, Maria Chiara Magnifico, Simona Nicole Barile, Francesca Massenzio, Antonella Pignataro, Federico M. Giorgi, Francesco Massimo Lasorsa, Barbara Monti
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-26 (2024)
Abstract Aspartate–glutamate carrier isoform 1 (AGC1) is a carrier responsible for the export of mitochondrial aspartate in exchange for cytosolic glutamate and is part of the malate–aspartate shuttle, essential for the balance of reducing equiva
Externí odkaz:
https://doaj.org/article/7790a48d279b4cc18bdc2e5d13eff545
Autor:
Federico M Giorgi, Gonzalo Lopez, Jung H Woo, Brygida Bisikirska, Andrea Califano, Mukesh Bansal
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109569 (2014)
Systematic, high-throughput dissection of causal post-translational regulatory dependencies, on a genome wide basis, is still one of the great challenges of biology. Due to its complexity, however, only a handful of computational algorithms have been
Externí odkaz:
https://doaj.org/article/c75a1555b9944ab3a9bf6044883048e3
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85024 (2013)
Next Generation Sequencing is having an extremely strong impact in biological and medical research and diagnostics, with applications ranging from gene expression quantification to genotyping and genome reconstruction. Sequencing data is often provid
Externí odkaz:
https://doaj.org/article/43e0dc820ed44c82ba28223aac613d29
Autor:
Malgorzata eRyngajllo, Liam eChilds, Marc eLohse, Federico M Giorgi, Anja eLude, Joachim eSelbig, Bjoern eUsadel
Publikováno v:
Frontiers in Plant Science, Vol 2 (2011)
Despite the growing volume of experimentally validated knowledge about the subcellular localization of plant proteins, a well performing in-silico prediction tool is still a necessity. Existing tools, which employ information derived from protein seq
Externí odkaz:
https://doaj.org/article/8841e9adbc8f40f6831b96701f61bcd8
Autor:
Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Metastatic cancer cells exploit Epithelial-mesenchymal-transition (EMT) to enhance their migration, invasion, and resistance to treatments. Recent studies highlight that elevated levels of copper are implicated in cancer progressi
Externí odkaz:
https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8
Autor:
Daria Messelodi, Silvia Strocchi, Salvatore Nicola Bertuccio, Pascale Baden, Valentina Indio, Federico M. Giorgi, Alberto Taddia, Salvatore Serravalle, Sabrina Valente, Alessio di Fonzo, Emanuele Frattini, Roberto Bernardoni, Annalisa Pession, Daniela Grifoni, Michela Deleidi, Annalisa Astolfi, Andrea Pession
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Gaucher Disease (GD), the most common lysosomal disorder, arises from mutations in the GBA1 gene and is characterized by a wide spectrum of phenotypes, ranging from mild hematological and visceral involvement to severe neurological disease.
Externí odkaz:
https://doaj.org/article/9bd17c548d7444108e9aef7cad700e02
Publikováno v:
Genes, Vol 13, Iss 12, p 2240 (2022)
The molecular mechanisms and gene regulatory networks sustaining cell proliferation in neuroblastoma (NBL) cells are still not fully understood. In this tumor context, it has been proposed that anti-proliferative drugs, such as the pan-HDAC inhibitor
Externí odkaz:
https://doaj.org/article/b5852926a6584550b850c53f6a100448