Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Federico Giannini"'
Publikováno v:
CHIMIA, Vol 66, Iss 10 (2012)
NMR spectroscopy has proved extremely beneficial in the investigation of inorganic drugs from the time that cisplatin was first introduced into the clinic more than 30 years ago. Both 195Pt and 15N NMR were used in early studies and made a major cont
Externí odkaz:
https://doaj.org/article/1bcb8dc87c0d41ff9fc4cc2883263737
Autor:
Julien Furrer, Andrew Hemphill, Federico Giannini, Peter Bütikofer, Jennifer Jelk, Georg Süss-Fink, Vreni Balmer, David Stíbal
Publikováno v:
Jelk, Jennifer; Balmer, Vreni; Stibal, David; Giannini, Federico; Süss-Fink, Georg; Bütikofer, Peter; Furrer, Julien; Hemphill, Andrew (2019). Anti-parasitic dinuclear thiolato-bridged arene ruthenium complexes alter the mitochondrial ultrastructure and membrane potential in Trypanosoma brucei bloodstream forms. Experimental parasitology, 205, p. 107753. Elsevier 10.1016/j.exppara.2019.107753
rypanosoma brucei causes human African trypanosomiasis and Nagana disease in cattle, imposing substantial medical and economic burden in sub-Saharan Africa. The current treatments have limitations, including the requirement for elaborated protocols,
Autor:
Vreni Balmer, Julien Furrer, Afonso P. Basto, Riccardo Rubbiani, Andrew Hemphill, Joachim Müller, David Stíbal, Gilles Gasser, Georg Süss-Fink, Federico Giannini, Nicoleta Anghel
Publikováno v:
Metallomics
Metallomics, Royal Society of Chemistry, 2019, ⟨10.1039/c8mt00307f⟩
Silva Pinto Basto, Afonso; Anghel, Nicoleta; Rubbiani, Riccardo; Müller, Joachim; Stibal, David; Giannini, Federico; Süss-Fink, Georg; Balmer, Vreni; Gasser, Gilles; Furrer, Julien; Hemphill, Andrew (2019). Targeting of the mitochondrion by dinuclear thiolato-bridged arene ruthenium complexes in cancer cells and in the apicomplexan parasite Neospora caninum. Metallomics, 11(2), pp. 462-474. Royal Society of Chemistry 10.1039/C8MT00307F
Metallomics, Royal Society of Chemistry, 2019, ⟨10.1039/c8mt00307f⟩
Silva Pinto Basto, Afonso; Anghel, Nicoleta; Rubbiani, Riccardo; Müller, Joachim; Stibal, David; Giannini, Federico; Süss-Fink, Georg; Balmer, Vreni; Gasser, Gilles; Furrer, Julien; Hemphill, Andrew (2019). Targeting of the mitochondrion by dinuclear thiolato-bridged arene ruthenium complexes in cancer cells and in the apicomplexan parasite Neospora caninum. Metallomics, 11(2), pp. 462-474. Royal Society of Chemistry 10.1039/C8MT00307F
A library of 18 dinuclear-thiolato bridged arene ruthenium complexes, some of which with demonstrated activity against cancer cells, was screened for activity against a transgenic Neospora caninum strain that constitutively expresses beta-galactosida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3d7005d711c8892665040eb897f90e
https://hal.archives-ouvertes.fr/hal-01977905/document
https://hal.archives-ouvertes.fr/hal-01977905/document
Usually people consider morality traits to be highly valuable, both in themselves and in others. Moreover, they tend to select moral groups and are often motivated to protect the positive identity of their groups by derogating immoral ingroup members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17ec7486d9b7b88a705cb4f9dccea5c
http://hdl.handle.net/11365/1156365
http://hdl.handle.net/11365/1156365
Autor:
Georg Süss-Fink, Lydia E. H. Paul, Federico Giannini, Julien Furrer, Thomas Roder, Lennart Geiser, Bruno Therrien
Publikováno v:
Journal of Organometallic Chemistry. 783:40-45
A new series of cationic dinuclear arene ruthenium complexes bridged by three thiophenolato ligands, [(η6-arene)2Ru2(μ2-SR)3]+ with arene = indane, R = met: 1 (met = 4-methylphenyl); R = mco: 4 (mco = 4-methylcoumarin-7-yl); arene = biphenyl, R = m
Autor:
Julien Furrer, Georg Süss-Fink, Lydia E. H. Paul, Marco Bartoloni, Jean-Louis Reymond, Federico Giannini
Publikováno v:
MedChemCom
In order to improve the water-solubility of dinuclear thiolato-bridged arene ruthenium complexes, a new series was synthesized by conjugating octaarginine, octalysine, and cyclo[Lys-Arg-Gly-Asp-D-Phe] using chloroacetyl thioether (ClAc) ligation, res
Autor:
Riccardo Rubbiani, Afonso P. Basto, Julien Furrer, Joachim Müller, Federico Giannini, Gilles Gasser, Georg Süss-Fink, David Stíbal, Vreni Balmer, Andrew Hemphill
Publikováno v:
Silva Pinto Basto, Afonso; Müller, Joachim; Rubbiani, Riccardo; Stibal, David; Giannini, Federico; Süss-Fink, Georg; Balmer, Vreni; Hemphill, Andrew; Gasser, Gilles; Furrer, Julien (2017). Characterization of the Activities of Dinuclear Thiolato-Bridged Arene Ruthenium Complexes against Toxoplasma gondii. Antimicrobial agents and chemotherapy, 61(9), e01031-17. American Society for Microbiology 10.1128/AAC.01031-17
The in vitro effects of 18 dinuclear thiolato-bridged arene ruthenium complexes (1 monohiolato compound, 4 dithiolato compounds, and 13 trithiolato compounds), originally designed as anticancer agents, on the apicomplexan parasite Toxoplasma gondii g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c92ee04427781e8e9ec2518f0c0d7b
Autor:
Federico Giannini, Julien Furrer, Georg Süss-Fink, Lydia E. H. Paul, Bruno Therrien, David Stíbal
Publikováno v:
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
The monothiolato complexes [(η6-p-MeC6H4iPr)2Ru2Cl2(μ-Cl)(μ-SR)] with R = CH2C6H5 (1), p-CH2C6H4NO2 (2), C10H15 (3), m-9-B10C2H11 (4) were synthesized by treating [(η6-p-MeC6H4iPr)2Ru2Cl2(μ-Cl)2] with the corresponding thiols RSH. The reaction o
Publikováno v:
NEW JOURNAL OF CHEMISTRY
A new series of cationic dinuclear p-cymene ruthenium complexes bridged by three thiophenolato ligands containing various substituents mainly in meta and ortho positions, [(η6-p-MeC6H4Pri)2Ru2(μ2-SR)3]+ (R = 3-C6H4Me: 1; R = 3-C6H4OMe: 2; R = 3-C6H
Autor:
Mona A. Furrer, Amine Garci, Federico Giannini, Patrick Trouillas, Catherine M. Clavel, Emmanuel Denoyelle-Di-Muro, Georg Süss-Fink, Paul J. Dyson, Julien Furrer, Bruno Therrien
Publikováno v:
CHEMISTRY-A EUROPEAN JOURNAL
Chemistry: A European Journal
Chemistry: A European Journal
Hexanuclear thiolato-bridged arene ruthenium metalla-prisms of the general formula [(p-cymene)(6)Ru(6)(SR)(6)(tpt)(2) ](6+) (R=CH(2)Ph, CH(2)C(6)H(4)-p-tBu, CH(2)CH(2)Ph; tpt=2,4,6-tris(4-pyridyl)-1,3,5-triazine), obtained from the dinuclear precurso