Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Federico F. De Ponti"'
Publikováno v:
JHEP Reports, Vol 6, Iss 11, Pp 101196- (2024)
Summary: Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a spectrum of disease states ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH), which can eventually lead to the development o
Externí odkaz:
https://doaj.org/article/44b2faec108940e49c66d8bb9c0cd8db
Autor:
Wouter Claeys, Daan Verhaege, Griet Van Imschoot, Elien Van Wonterghem, Lore Van Acker, Laura Amelinck, Federico F. De Ponti, Charlotte Scott, Anja Geerts, Christophe Van Steenkiste, Lien Van Hoecke, Roosmarijn E. Vandenbroucke
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Microglia, the resident macrophages of the central nervous system (CNS), play a critical role in CNS homeostasis and neuroinflammation. Pexidartinib (PLX3397), a colony-stimulating factor 1 (CSF1) receptor inhibitor, is widely used to deplete microgl
Externí odkaz:
https://doaj.org/article/c70ceb55caac4437bf8ff60c5097c15a
Publikováno v:
Clinical Science. 136:1111-1115
Non-alcoholic steatohepatitis (NASH) and associated end-stage liver disease is a growing cause of concern throughout the Western world. It constitutes a significant clinical burden for which therapeutic approaches are very limited. Over the last year
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c8b01b0b43b2483ee394c24395fcc4
https://doi.org/10.1042/cs20220258
https://doi.org/10.1042/cs20220258
Autor:
Kevin De Muynck, Bart Vanderborght, Federico F. De Ponti, Eva Gijbels, Sophie Van Welden, Martin Guilliams, Charlotte L. Scott, Alain Beschin, Mathieu Vinken, Sander Lefere, Anja Geerts, Xavier Verhelst, Hans Van Vlierberghe, Lindsey Devisscher
Primary sclerosing cholangitis (PSC) is an idiopathic chronic immune-mediated cholestatic liver disease characterized by fibro-inflammatory bile duct strictures, progressive hepatobiliary fibrosis, and gut-liver axis disruption. The pathophysiology o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428ce81d88b3036d6b496d6fcace25d6
https://doi.org/10.1016/j.ajpath.2022.12.008
https://doi.org/10.1016/j.ajpath.2022.12.008
Publikováno v:
Nature Immunology. 23:820-822
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::682759f86c82e97086d348a2c26d32e3
https://doi.org/10.1038/s41590-022-01214-1
https://doi.org/10.1038/s41590-022-01214-1
Autor:
Xenia Ficht, Marc Bajénoff, Alexandre P. Benechet, Matteo Iannacone, Federica Moalli, Svetoslav Chakarov, José M. Garcia-Manteiga, Paola Zordan, Pietro Di Lucia, Francesco Andreata, Chiara Laura, Luca G. Guidotti, Marta Mainetti, Giorgia De Simone, Camille Blériot, Elisa Bono, Gioia Ambrosi, Leonardo Giustini, Valeria Fumagalli, Stefano Gilotto, Micol Ravà, Federico F. De Ponti, Florent Ginhoux
Publikováno v:
Immunity
Immunity, Elsevier, 2021, 54 (9), pp.2089-2100.e8. ⟨10.1016/j.immuni.2021.05.005⟩
Immunity, 2021, 54 (9), pp.2089-2100.e8. ⟨10.1016/j.immuni.2021.05.005⟩
IMMUNITY
Immunity, Elsevier, 2021, 54 (9), pp.2089-2100.e8. ⟨10.1016/j.immuni.2021.05.005⟩
Immunity, 2021, 54 (9), pp.2089-2100.e8. ⟨10.1016/j.immuni.2021.05.005⟩
IMMUNITY
Summary Kupffer cells (KCs) are highly abundant, intravascular, liver-resident macrophages known for their scavenger and phagocytic functions. KCs can also present antigens to CD8+ T cells and promote either tolerance or effector differentiation, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc00c3e7901b9a5280f393fb3674b26
https://doi.org/10.1016/j.immuni.2021.05.005
https://doi.org/10.1016/j.immuni.2021.05.005
Autor:
Martin Guilliams, Johnny Bonnardel, Birthe Haest, Bart Vanderborght, Camille Wagner, Anneleen Remmerie, Anna Bujko, Liesbet Martens, Tinne Thoné, Robin Browaeys, Federico F. De Ponti, Bavo Vanneste, Christian Zwicker, Freya R. Svedberg, Tineke Vanhalewyn, Amanda Gonçalves, Saskia Lippens, Bert Devriendt, Eric Cox, Giuliano Ferrero, Valerie Wittamer, Andy Willaert, Suzanne J.F. Kaptein, Johan Neyts, Kai Dallmeier, Peter Geldhof, Stijn Casaert, Bart Deplancke, Peter ten Dijke, Anne Hoorens, Aude Vanlander, Frederik Berrevoet, Yves Van Nieuwenhove, Yvan Saeys, Wouter Saelens, Hans Van Vlierberghe, Lindsey Devisscher, Charlotte L. Scott
Publikováno v:
Cell, 185(2), 379-+. CELL PRESS
Cell
CELL
Cell
CELL
Summary The liver is the largest solid organ in the body, yet it remains incompletely characterized. Here we present a spatial proteogenomic atlas of the healthy and obese human and murine liver combining single-cell CITE-seq, single-nuclei sequencin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f651fe94b9b37bc43a0314d9223ff7f
https://infoscience.epfl.ch/record/292065
https://infoscience.epfl.ch/record/292065