Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Federico Cucchiara"'
Autor:
Stefania Crucitta, Federico Cucchiara, Riccardo Marconcini, Alessandra Bulleri, Simona Manacorda, Annalisa Capuano, Dania Cioni, Amedeo Nuzzo, Evert de Jonge, Ron H. J. Mathjissen, Emanuele Neri, Ron H. N. van Schaik, Stefano Fogli, Romano Danesi, Marzia Del Re
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Introduction: Immune checkpoint inhibitors (ICIs) represent the standard therapy for metastatic melanoma. However, a few patients do not respond to ICIs and reliable predictive biomarkers are needed.Methods: This pilot study investigates the associat
Externí odkaz:
https://doaj.org/article/8e14b0fdf9504f27a43e5891cecfd741
Autor:
Eleonora Pardini, Federico Cucchiara, Sara Palumbo, Giulia Tarrini, Alessia Di Vita, Fabio Coppedè, Vanessa Nicolì, Melania Guida, Michelangelo Maestri, Roberta Ricciardi, Vittorio Aprile, Marcello C. Ambrogi, Serena Barachini, Marco Lucchi, Iacopo Petrini
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThymic epithelial tumors are rare malignant neoplasms that are frequently associated with paraneoplastic syndromes, especially myasthenia gravis. GTF2I is an oncogene mutated in a subgroup of thymomas that is reputed to drive their growth.
Externí odkaz:
https://doaj.org/article/1317aeb6d08d463381873c513bc9a53d
Autor:
Marzia Del Re, Stefania Crucitta, Federico Paolieri, Federico Cucchiara, Elena Verzoni, Francesco Bloise, Raffaele Ciampi, Chiara Mercinelli, Annalisa Capuano, Liberata Sportiello, Antonia Martinetti, Giuseppe Procopio, Luca Galli, Camillo Porta, Sergio Bracarda, Romano Danesi
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-9 (2022)
Abstract Background Despite the increasing number of treatment options, reliable prognostic/predictive biomarkers are still missing for patients affected by metastatic clear cell renal cell carcinoma (mccRCC). Methods Patients with mccRCC undergoing
Externí odkaz:
https://doaj.org/article/fef037278a2f4851b867577c0a56cf60
Autor:
Federico Cucchiara, Giacomo Luci, Noemi Giannini, Filippo Sean Giorgi, Paola Orlandi, Marta Banchi, Antonello Di Paolo, Francesco Pasqualetti, Romano Danesi, Guido Bocci
Publikováno v:
Pharmacological Research, Vol 181, Iss , Pp 106290- (2022)
Glioblastoma multiforme (GBM) is an aggressive brain tumor, often occurring with seizures managed with antiepileptic drugs, such as levetiracetam (LEV). This study is aimed at associating progression-free survival (PFS) and overall survival (OS) of G
Externí odkaz:
https://doaj.org/article/53635defdfb448509408cfa093585276
Autor:
Rossella Bruno, Marzia Del Re, Federico Cucchiara, Iacopo Petrini, Greta Alì, Stefania Crucitta, Agnese Proietti, Simona Valleggi, Antonio Chella, Romano Danesi, Gabriella Fontanini
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Resistance to EGFR tyrosin kinase inhibitors (TKI) inevitably occurs. Here it is reported the case of a young patient affected by lung adenocarcinoma harboring the L858R EGFR sensitive mutation. The patient developed multiple TKI resistance mechanism
Externí odkaz:
https://doaj.org/article/73c6bb1252184cc9a941bfeeaf8e1e4c
Autor:
Federico Cucchiara, Marzia Del Re, Simona Valleggi, Chiara Romei, Iacopo Petrini, Maurizio Lucchesi, Stefania Crucitta, Eleonora Rofi, Annalisa De Liperi, Antonio Chella, Antonio Russo, Romano Danesi
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BackgroundEGFR-positive Non-small Cell Lung Cancer (NSCLC) is a dynamic entity and tumor progression and resistance to tyrosine kinase inhibitors (TKIs) arise from the accumulation, over time and across different disease sites, of subclonal genetic m
Externí odkaz:
https://doaj.org/article/51fde2b3d39e4b779b98cf5e2303f480
Autor:
Francesco Pepe, Umberto Malapelle, Giancarlo Troncone, Caterina De Luca, Pasquale Pisapia, Alessandro Russo, Christian Rolfo, Caterina Fumagalli, Elena Guerini-Rocco, Antonio Passaro, Filippo de Marinis, Marzia Del Re, Ilaria Attili, Federico Cucchiara, Romano Danesi, Lorenzo Spaggiari
Publikováno v:
ESMO Open, Vol 5, Iss 5 (2020)
The advances in understanding the inherited biological mechanisms of non-small cell lung cancer harbouring epidermal growth factor receptor (EGFR) mutations led to a significant improvement in the outcomes of patients treated with EGFR tyrosine kinas
Externí odkaz:
https://doaj.org/article/4dd8ec3dfc374e4ea3905be9f5da3324
Autor:
Antonello Di Paolo, Elena Arrigoni, Giacomo Luci, Federico Cucchiara, Romano Danesi, Sara Galimberti
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
In recent years, many efforts have been addressed to the growing field of precision medicine in order to offer individual treatments to every patient on the basis of his/her genetic background. Formerly adopted to achieve new disease classifications
Externí odkaz:
https://doaj.org/article/901df55ebf1c4005b4ea8d40fb78105f
Autor:
Giacomo Luci, Federico Cucchiara, Laura Ciofi, Francesca Mattioli, Marianna Lastella, Romano Danesi, Antonello Di Paolo
Publikováno v:
Separations, Vol 8, Iss 5, p 63 (2021)
Mitotane (DDD) is prescribed in adrenocortical renal carcinoma. Its principal metabolite, dichlorodiphenylethene (DDE), can accumulate in fat tissues and from a toxicological point of view, is probably more interesting than the other metabolite dichl
Externí odkaz:
https://doaj.org/article/6256beac6cd04ee991d1377b76f2856c
Autor:
Federico Cucchiara, Iacopo Petrini, Antonio Passaro, Ilaria Attili, Stefania Crucitta, Eleonora Pardini, Filippo de Marinis, Romano Danesi, Marzia Del Re
Publikováno v:
Clinical Lung Cancer. 23:510-521
Small cell lung cancer (SCLC) is an aggressive tumor, and despite its sensitivity to chemotherapy and radiotherapy, patients usually have a short survival. There are no clinically relevant predictive factors of responses to therapies, and therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea53a27e9f87afd4310e2afc781428a8
https://doi.org/10.1016/j.cllc.2022.05.012
https://doi.org/10.1016/j.cllc.2022.05.012