Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Federico Ceriani"'
Autor:
Adam J. Carlton, Jing-Yi Jeng, Fiorella C. Grandi, Francesca De Faveri, Ana E. Amariutei, Lara De Tomasi, Andrew O’Connor, Stuart L. Johnson, David N. Furness, Steve D.M. Brown, Federico Ceriani, Michael R. Bowl, Mirna Mustapha, Walter Marcotti
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114025- (2024)
Summary: Type I spiral ganglion neurons (SGNs) convey sound information to the central auditory pathway by forming synapses with inner hair cells (IHCs) in the mammalian cochlea. The molecular mechanisms regulating the formation of the post-synaptic
Externí odkaz:
https://doaj.org/article/003f391f46fe499b876a09eda87c4a9d
Autor:
Jing-Yi Jeng, Adam J. Carlton, Richard J. Goodyear, Colbie Chinowsky, Federico Ceriani, Stuart L. Johnson, Tsung-Chang Sung, Yelena Dayn, Guy P. Richardson, Michael R. Bowl, Steve D.M. Brown, Uri Manor, Walter Marcotti
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 355-370 (2022)
The transduction of acoustic information by hair cells depends upon mechanosensitive stereociliary bundles that project from their apical surface. Mutations or absence of the stereociliary protein EPS8 cause deafness in humans and mice, respectively.
Externí odkaz:
https://doaj.org/article/5942f8bc16104f7a85b0dffab23f1f8b
Autor:
Laura F. Corns, Stuart L. Johnson, Terri Roberts, Kishani M. Ranatunga, Aenea Hendry, Federico Ceriani, Saaid Safieddine, Karen P. Steel, Andy Forge, Christine Petit, David N. Furness, Corné J. Kros, Walter Marcotti
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Mechanoelectrical transducer (MET) channels on the tips of inner hair cells are essential for transducing auditory sensory information. Here, the authors show that disrupting MET channel function also prevents the preservation of normal inner hair ce
Externí odkaz:
https://doaj.org/article/ecfdf3bfbfef42019680748d1efaa1ea
Autor:
Liang Xu, Andrea Carrer, Francesco Zonta, Zhihu Qu, Peixiang Ma, Sheng Li, Federico Ceriani, Damiano Buratto, Giulia Crispino, Veronica Zorzi, Gaia Ziraldo, Francesca Bruno, Chiara Nardin, Chiara Peres, Flavia Mazzarda, Anna M. Salvatore, Marcello Raspa, Ferdinando Scavizzi, Youjun Chu, Sichun Xie, Xuemei Yang, Jun Liao, Xiao Liu, Wei Wang, Shanshan Wang, Guang Yang, Richard A. Lerner, Fabio Mammano
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Background: Mutations leading to changes in properties, regulation, or expression of connexin-made channels have been implicated in 28 distinct human hereditary diseases. Eight of these result from variants of connexin 26 (Cx26), a protein critically
Externí odkaz:
https://doaj.org/article/cc3dd804c27e4ae68e8efa44292bdd38
Autor:
Yang Yang, Kaitlin Murtha, Leslie K. Climer, Federico Ceriani, Pierce Thompson, Aubrey J. Hornak, Walter Marcotti, Dwayne D. Simmons
Publikováno v:
bioRxiv
Cochlear outer hair cells (OHCs) are responsible for the exquisite frequency selectivity and sensitivity of mammalian hearing. During development, the maturation of OHC afferent connectivity is refined by coordinated spontaneous Ca2+activity in both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7264bd08b01fc0ed610dea1c0587f2c0
https://doi.org/10.1101/2023.03.01.529895
https://doi.org/10.1101/2023.03.01.529895
Autor:
Adam J Carlton, Jing‐Yi Jeng, Fiorella C Grandi, Francesca De Faveri, Federico Ceriani, Lara De Tomasi, Anna Underhill, Stuart L Johnson, Kevin P Legan, Corné J Kros, Guy P Richardson, Mirna Mustapha, Walter Marcotti
Publikováno v:
The EMBO Journal. 42
Autor:
Adam J, Carlton, Jing-Yi, Jeng, Fiorella C, Grandi, Francesca, De Faveri, Federico, Ceriani, Lara, De Tomasi, Anna, Underhill, Stuart L, Johnson, Kevin P, Legan, Corné J, Kros, Guy P, Richardson, Mirna, Mustapha, Walter, Marcotti
Publikováno v:
The EMBO journalReferences.
Sensory-independent Ca
Autor:
Adam J Carlton, Michael R. Bowl, Julia Halford, Steve D.M. Brown, Jing-Yi Jeng, Walter Marcotti, Matthew R. Avenarius, Merle L. Gilbert, Kimimuepigha Ebisine, Peter G. Barr-Gillespie, Federico Ceriani, Anna Underhill
Publikováno v:
The Journal of Physiology
Key points Mechanoelectrical transduction at auditory hair cells requires highly specialized stereociliary bundles that project from their apical surface, forming a characteristic graded ‘staircase’ structure.The morphogenesis and maintenance of
Autor:
Jennifer Olt, Jing-Yi Jeng, Matthew C. Holley, Steve D. M. Brown, Stuart L. Johnson, Federico Ceriani, Michael R. Bowl, Walter Marcotti
Publikováno v:
J Physiol
Mammalian cochlear inner hair cells (IHCs) are specialized sensory receptors able to provide dynamic coding of sound signals. This ability is largely conferred by their ribbon synapses, which tether a large number of vesicles at the IHC’s presynapt
Autor:
Kaitlin E. Murtha, Yang Yang, Federico Ceriani, Jing-Yi Jeng, Leslie K. Climer, Forrest Jones, Jack Charles, Sai K. Devana, Aubrey J. Hornak, Walter Marcotti, Dwayne D. Simmons
Publikováno v:
Cell Calcium. 105:102613
In cochlear outer hair cells (OHCs), a network of Ca2+ channels, pumps and Ca2+-binding proteins (CaBPs) regulates the localization, spread, and magnitude of free Ca2+ ions. During early postnatal development, OHCs express three prominent mobile EF-h