Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Federico Casares"'
Publikováno v:
Journal of Human Hypertension. 24:713-720
It has been shown that vascular endothelial cells functionally express a local circuit autocrine-paracrine regulatory pathway driven by endogenously expressed chemically authentic morphine, its cognate opiate alkaloid-selective mu3 and mu4 receptors,
Autor:
George B. Stefano, Richard M. Kream, Sean Challenger, Kirk J. Mantione, Christopher Snyder, Joshua M. Samuel, Rohina Ramin, Federico Casares, Lismary Capellan
Publikováno v:
Journal of bioenergetics and biomembranes. 47(5)
The expression of morphine by plants, invertebrate, and vertebrate cells and organ systems, strongly indicates a high level of evolutionary conservation of morphine and related morphinan alkaloids as required for life. The prototype catecholamine, do
Autor:
Federico Casares, Yannick Goumon, Geert Baggerman, George B. Stefano, Wei Zhu, Bruce J. Brownawell
Publikováno v:
Molecular Brain Research. 88:155-160
Morphine and morphine-6-glucuronide, a morphine metabolite, have been identified and quantified in Mytilus edulis pedal ganglia at a level of 2.67+/-0.44 and 0.98+/-0.14 ng/ganglia, respectively by high performance liquid chromatography coupled to el
Autor:
Maria Bougaeva, Benjamin S. Weeks, George B. Stefano, Patrick Cadet, Federico Casares, Yannick Goumon, Bruce J. Brownawell, Wei Zhu
Publikováno v:
Molecular Brain Research. 81:177-180
Morphine was identified in the adrenal medulla chromaffin PC-12 cell line by reversed-phase HPLC, following liquid and solid extraction. The morphine corresponding HPLC fractions (1.746+/-0.615 ng of morphine/million cells) were further analyzed by g
Autor:
Yu Liu, Alan R. Hartman, Federico Casares, Harold I. Magazine, George B. Stefano, Thomas V. Bilfinger, Michael S. Goligorsky
Publikováno v:
Journal of Biological Chemistry. 270:30290-30293
Initial confinement of opiate receptors to the nervous system has recently been broadened to several other cell types. Based on the well established hypotensive effect of morphine, we hypothesized that endothelial cells may represent a target for thi
Autor:
Richard M, Kream, Melinda, Sheehan, Patrick, Cadet, Kirk J, Mantione, Wei, Zhu, Federico, Casares, George B, Stefano
Publikováno v:
Medical science monitor : international medical journal of experimental and clinical research. 13(12)
Biochemical, molecular and pharmacological evidence for two unique six-transmembrane helical (TMH) domain opiate receptors expressed from the micro opioid receptor (MOR) gene have been shown. Designated micro3 and micro4 receptors, both protein speci
Autor:
George B, Stefano, Ellen, Kim, Yu, Liu, Wei, Zhu, Federico, Casares, Kirk, Mantione, Dolisha A, Jones, Patrick, Cadet
Publikováno v:
Medical science monitor : international medical journal of experimental and clinical research. 10(2)
Nitric oxide (NO) has important physiological regulatory roles, i.e, vasodilation, neurotransmitter release, etc. Little is known about the processes in neural tissues, which stabilize microglia. This study attempts to answer this question by demonst
Autor:
George B, Stefano, Kirk, Mantione, Dolisha, Jones, Wei, Zhu, Federico, Casares, Patrick, Cadet
Publikováno v:
Neuro endocrinology letters. 25(1-2)
Pedal ganglia excised and maintained in culture for up to 2 h, release NO at low levels. The range can vary between 0 to 1.1 nM. Non-stimulated immunocytes do not significantly stimulate ganglionic NO release when incubated with pedal ganglia. Howeve
Autor:
George B, Stefano, Patrick, Cadet, Christos M, Rialas, Kirk, Mantione, Federico, Casares, Yannick, Goumon, Wei, Zhu
Publikováno v:
Advances in experimental medicine and biology. 521
Autor:
George B, Stefano, Patrick, Cadet, Wei, Zhu, Christos M, Rialas, Kirk, Mantione, Danielle, Benz, Rudy, Fuentes, Federico, Casares, Gregory L, Fricchione, Zoltan, Fulop, Brian, Slingsby
Publikováno v:
Neuro endocrinology letters. 23(2)
Through an extremely complicated equilibrium called homeostasis, all living organisms maintain their survival in the face of both externally and internally generated "stimuli". This apparent harmony is constantly challenged. Survival through successf