Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Federico Brianza"'
Autor:
Alexander Lederer, John A. Robinson, Kerstin Moehle, Thomas Klimkait, François Hamy, Vincent Brondani, Sergio Lociuro, Jean-Pierre Obrecht, Jan Willem Vrijbloed, Christian Ludin, Frank O. Gombert, Federico Brianza, Jürg Zumbrunn, Reshmi Mukherjee, Barbara Romagnoli, Heiko Henze, Steven J. DeMarco, Daniel Obrecht
Publikováno v:
CHIMIA, Vol 61, Iss 4 (2007)
Novel, highly potent CXCR4 inhibitors with good pharmacokinetic properties were obtained by applying PEM technology starting from the naturally occurring ?-hairpin peptide polyphemusin II. The design involved incorporation of key residues from polyph
Externí odkaz:
https://doaj.org/article/8217e99491f84874af190a472277fb21
Autor:
Lisa Long, Katrine B V Greve, Patrick Roussel, Philipp Knechtle, Jean Philippe Meyer, Federico Brianza, Harald Heider, Melanie Diefenbacher, Christophe Folly, Museer A. Lone, Roger Schneiter, Alexandra Santana Sorensen, Mahmoud A. Ghannoum
Publikováno v:
Antimicrob Agents Chemother.
Human fungal infections represent a therapeutic challenge. Although effective strategies for treatment are available, resistance is spreading, and many therapies have unacceptable side effects. A clear need for novel antifungal targets and molecules
Autor:
Steven J. Demarco, Kerstin Moehle, Christian Ludin, Thomas Klimkait, François Hamy, Federico Brianza, Vincent Brondani, Sergio Lociuro, Alexander Lederer, Frank Gombert, John A. Robinson, Jürg Zumbrunn, Reshmi Mukherjee, Heiko Henze, Jean-Pierre Obrecht, Daniel Obrecht, Barbara Romagnoli, Jan Wim Vrijbloed
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:8396-8404
Novel highly potent CXCR4 inhibitors with good pharmacokinetic properties were designed and optimized starting from the naturally occurring beta-hairpin peptide polyphemusin II. The design involved incorporating important residues from polyphemusin I
Publikováno v:
From Genome to Proteome: Advances in the Practice and Application of Proteomics
Functional proteomic methods have been developed and applied to the investigation of signal transduction systems involving platelet-derived growth factor (PDGF), endothelin and bradykinin receptors. Mouse fibroblast cells have been stimulated with PD
Autor:
Daniel Obrecht, Thomas Klimkait, François Hamy, Heiko Henze, Vincent Brondani, Sergio Lociuro, Barbara Romagnoli, Kerstin Moehle, Alexander Lederer, Jean-Pierre Obrecht, Steven J. Demarco, Jan Wim Vrijbloed, Christian Ludin, Frank Gombert, Reshmi Mukherjee, John A. Robinson, Jürg Zumbrunn, Federico Brianza
Publikováno v:
CHIMIA, Vol 61, Iss 4 (2007)
Novel, highly potent CXCR4 inhibitors with good pharmacokinetic properties were obtained by applying PEM technology starting from the naturally occurring ?-hairpin peptide polyphemusin II. The design involved incorporation of key residues from polyph