Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Federico Arcamone"'
Autor:
Federico Arcamone
Publikováno v:
Bulletin des Sociétés Chimiques Belges. 91:1003-1017
The chemical manipulation of the aminosugar, daunosamine, has resulted in the development of new interesting doxorubicin analogues, namely 4′-epi- and 4′-deoxydoxorubicin, whereas the total synthesis of new aglycones has provided new structural t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bc6d5af0198e3e998cbf8ecccfa184e
https://doi.org/10.1002/bscb.19820911207
https://doi.org/10.1002/bscb.19820911207
Autor:
Fabio Animati, Federico Arcamone, Marco Berettoni, Amalia Cipollone, L. Olivieri, D. Palomba, Carlo Alberto Maggi
Publikováno v:
Tetrahedron Letters. 43:2867-2871
Synthesis of the novel anthracycline 14-fluorodoxorubicin is described. A key step in the synthesis is the hydrolysis of 14-bromo,14-fluoro derivative 14 with AgBF 4 and DMSO, to give the geminal fluorohydrin system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6a4c77f362ee3e1d268e97dff7d9692
https://doi.org/10.1016/s0040-4039(02)00299-x
https://doi.org/10.1016/s0040-4039(02)00299-x
Autor:
A. Lippi, Marco Criscuoli, Paola Cucchi, Alessandro Lecci, Laura Quartara, C.A. Maggi, Antonio Giachetti, Federico Arcamone, Manuela Tramontana, R.-M. Catalioto, Sandro Giuliani, Riccardo Patacchini, Anna Rita Renzetti, D. Giannotti
Publikováno v:
British Journal of Pharmacology. 123:81-91
1. The pharmacological profile was studied of MEN 11420, or cyclo[[Asn(beta-D-GlcNAc)-Asp-Trp-Phe-Dap-Leu]cyclo(2beta-5beta )], a glycosylated derivative of the potent, selective, conformationally-constrained tachykinin NK2 receptor antagonist MEN 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ae5ffc76f183511156e051e56572e58
https://doi.org/10.1038/sj.bjp.0701587
https://doi.org/10.1038/sj.bjp.0701587
Autor:
Rosanna Supino, Mario Bigioni, Amalia Cipollone, Michelandrea De Cesare, Claudia Caserini, Fabio Animati, Graziella Pratesi, Anna Maria Casazza, Edith Monteagudo, Marco Berettoni, Stefano Manzini, Franco Zunino, Andrea Madami, Paolo Lombardi, Federico Arcamone, Donatella Polizzi, Carmela Salvatore, Giovanni Capranico, Sabina C. Righetti, Maurizio Franciotti
Publikováno v:
Scopus-Elsevier
Background: Although doxorubicin re mains one of the most effective agent for the treatment of solid tumors, then is an intensive effort to synthesize doxo rubicin analogues (compounds with similar chemical structures) that may have improved antitumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb82281554b76494411de2e15b458246
https://doi.org/10.1093/jnci/89.16.1217
https://doi.org/10.1093/jnci/89.16.1217
Autor:
Zanella Stefania, Giuseppe Giannini, Stefania Bonazzi, Federico Arcamone, Anna Garbesi, Massimo L. Capobianco
Publikováno v:
Nucleic Acids Research. 25:2121-2128
Conjugation of an anthracycline to a triplex-forming oligonucleotide (TFO) allows delivery of this drug to a specific DNA site, preserving the intercalation geometry of this class of anticancer agents. Conjugate 11, in which the TFO is linked via a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50aaa592573ae722af32ca6d9e4ef56
https://doi.org/10.1093/nar/25.11.2121
https://doi.org/10.1093/nar/25.11.2121
Publikováno v:
Carbohydrate Research. 300:11-16
The solution conformation of 4-demethoxy-7- O -[2,6-dideoxy-4- O -(2,3,6-trideoxy-3-amino- α -l-lyxo-hexopyranosyl)- α -l-lyxo- hexopyranosyl]adriamicinone, the first doxorubicin disaccharide analogue to be reported, has been analysed using nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed10dc82876cb842f6a158c28f2b7647
https://doi.org/10.1016/s0008-6215(97)00024-4
https://doi.org/10.1016/s0008-6215(97)00024-4
Autor:
Carlo Alberto Maggi, Daniela Pinzani, Anna Maria Papini, Federico Arcamone, Mauro Ginanneschi, Laura Quartara, G. Rapi, Mario Chelli, Riccardo Patacchini, Maria E. Vallecchi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:367-372
The influence of glycosylation on the structure-activity relationship of the tachykinin antagonist MEN 10376 and of its minimal active fragment MEN 10414 was investigated. The antagonist activity was preserved only when β-d-glucosylated Tyr, Ser and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfb018759d19b8ad6c04499bc23e2058
https://doi.org/10.1016/0960-894x(96)00039-x
https://doi.org/10.1016/0960-894x(96)00039-x
Autor:
Alessandro Giolitti, Antonio Guidi, Federico Arcamone, F. Canfarini, Vittorio Pestellini, Franco Pasqui
Publikováno v:
Tetrahedron. 52:185-198
The synthesis of different anthracyclines of the daunorubicin family, fluorinated at position 8 or 10 is described. The 8-fluoroderivatives ( 2a-c ) were obtained by glycosylation of the corresponding fluorinated aglycones. The 10-fluoroderivatives (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::374d25fada3978876bbc257ea9df68f3
https://doi.org/10.1016/0040-4020(95)00892-c
https://doi.org/10.1016/0040-4020(95)00892-c
Autor:
Vittorio Pestellini, Enzo Perrotta, Roberta Sperrung, Giuseppe Satta, Maria Altamura, Grazia Angela Morandotti, Federico Arcamone, Giuseppe Cascio, Piero Sbraci
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:555-558
The new penem antibiotic Men 10700 (3), bearing an amino acid derived amide as C-2 side chain, was synthesized. Men 10700 exhibited high potency and a broad spectrum of activity against Gram positive and Gram negative microorganisms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0f18a20581bd660baca7985ec933287
https://doi.org/10.1016/0960-894x(95)00072-2
https://doi.org/10.1016/0960-894x(95)00072-2
Autor:
Luigi Gomez Paloma, Fabio Animati, Paolo Lombardi, Aldo Galeone, Federico Arcamone, Maria R. Conte, Luciano Mayol, Cristina Rossi, Patrizia Felicetti
Publikováno v:
Journal of Medicinal Chemistry. 38:1140-1149
In the course of a study aimed at the synthesis of pyrrole amidine carboxamide DNA-binding agents as novel pharmacological agents, a series of carbamoyl analogues of distamycin, containing an increasing number of pyrrole units, have been obtained by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80376e3e6c2aa11c54895a616aff3305
https://doi.org/10.1021/jm00007a011
https://doi.org/10.1021/jm00007a011