Výsledky vyhledávání - "Federico Abbiati"

Akademický článek

Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation

Autor: Gaia Cermenati, Federico Abbiati, Solei Cermenati, Elisabetta Brioschi, Alessandro Volonterio, Guido Cavaletti, Enrique Saez, Emma De Fabiani, Maurizio Crestani, Luis M. Garcia-Segura, Roberto C. Melcangi, Donatella Caruso, Nico Mitro

Publikováno v: Journal of Lipid Research, Vol 53, Iss 2, Pp 300-310 (2012)

Diabetic peripheral neuropathy (DPN) is characterized by myelin abnormalities; however, the molecular mechanisms underlying such deficits remain obscure. To uncover the effects of diabetes on myelin alterations, we have analyzed myelin composition. I

Externí odkaz: https://doaj.org/article/537aaa785a8d4d66a8124a6e26b33788

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Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress

Autor: Paola Devoto, Valentina Bini, Marco Bortolato, Donatella Caruso, Roberto Frau, Alberto Casti, Federico Abbiati

Publikováno v: Schizophrenia Research. 168:640-648

Background Cogent evidence has shown that schizophrenia vulnerability is enhanced by psychosocial stress in adolescence, yet the underpinnings of this phenomenon remain elusive. One of the animal models that best capture the relationship between juve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44e3e7274faf86f9ce991ef3a3ec093
https://doi.org/10.1016/j.schres.2015.04.044

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Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy

Autor: Donatella Caruso, Emma De Fabiani, Nico Mitro, Luis M. Garcia-Segura, Elisabetta Brioschi, Federico Abbiati, Iñigo Azcoitia, Matteo Audano, Silvia Giatti, Roberto Cosimo Melcangi, Maurizio Crestani, Gaia Cermenati

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 143:115-121

Diabetic peripheral neuropathy causes a decrease in the levels of dihydroprogesterone and 5α-androstane-3α,17β-diol (3α-diol) in the peripheral nerves. These two neuroactive steroids exert protective effects, by mechanisms that still remain elusi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96768c04ff2013fda512d7fea3ae794a
https://doi.org/10.1016/j.jsbmb.2014.02.015

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Comparison of plasma and cerebrospinal fluid levels of neuroactive steroids with their brain, spinal cord and peripheral nerve levels in male and female rats

Autor: Roberto Cosimo Melcangi, Federico Abbiati, Donato Calabrese, Luis M. Garcia-Segura, Marzia Pesaresi, Donatella Caruso, Silvia Giatti

Publikováno v: Psychoneuroendocrinology. 38:2278-2290

Physiological changes and pathological alterations in the nervous system of rodents are associated with modifications in the levels of neuroactive steroids in the brain, spinal cord and/or peripheral nerves. Measures of tissue levels of steroids in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81b10d1e654c76b3d539d22a85bf3af
https://doi.org/10.1016/j.psyneuen.2013.04.016

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Neuroactive Steroid Levels are Modified in Cerebrospinal Fluid and Plasma of Post‐Finasteride Patients Showing Persistent Sexual Side Effects and Anxious/Depressive Symptomatology

Autor: Federico Abbiati, Guido Cavaletti, Donatella Caruso, Donato Calabrese, Fabrizio Piazza, Silvia Giatti, Roberto Cosimo Melcangi

Publikováno v: The Journal of Sexual Medicine. 10:2598-2603

Introduction Observations performed in a subset of subjects treated with finasteride (an inhibitor of the enzyme 5α‐reductase) for male pattern hair loss seem to indicate that sexual dysfunction as well as anxious/depressive symptomatology may occ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e8222670c327d5b5aa8fad6efb9966
https://doi.org/10.1111/jsm.12269

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Neuroprotective Effects of Progesterone in Chronic Experimental Autoimmune Encephalomyelitis

Autor: Silvia Giatti, Elisa Ballarini, Luis M. Garcia-Segura, Guido Cavaletti, Donato Calabrese, Marzia Pesaresi, Barbara Viviani, Federico Abbiati, Donatella Caruso, Roberta Rigolio, Roberto Cosimo Melcangi, María Santos-Galindo, Mariaserena Boraso

Publikováno v: Journal of Neuroendocrinology. 24:851-861

Observations so far obtained in experimental autoimmune encephalomyelitis (EAE) have revealed the promising neuroprotective effects exerted by progesterone (PROG). The findings suggest that this neuroactive steroid may potentially represent a therape

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4605067ca01a40b64e4c71b492db26f
https://doi.org/10.1111/j.1365-2826.2012.02284.x

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Modifications of Neuroactive Steroid Levels in an Experimental Model of Nigrostriatal Degeneration: Potential Relevance to the Pathophysiology of Parkinson’s Disease

Autor: Roberto Cosimo Melcangi, Donatella Caruso, Giovanna Levandis, Marie Therese Armentero, Federico Abbiati, Fabio Blandini

Publikováno v: Journal of Molecular Neuroscience. 46:177-183

An important link between neuroactive steroids and neurodegenerative disorders has recently been suggested. Indeed, in several neurodegenerative experimental models the levels of neuroactive steroids are affected and their administration exerts neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46016de0d13447471c92aff60c35e277
https://doi.org/10.1007/s12031-011-9570-y

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Activation of the Liver X Receptor Increases Neuroactive Steroid Levels and Protects from Diabetes-Induced Peripheral Neuropathy

Autor: Enrique Saez, Alessandro Volonterio, Omar Maschi, Marzia Pesaresi, Silvia Giatti, Federico Abbiati, Guido Cavaletti, Gaia Cermenati, Nico Mitro, Roberto Bianchi, Roberto Cosimo Melcangi, Donatella Caruso

Publikováno v: The Journal of Neuroscience. 30:11896-11901

Neuroactive steroids act in the peripheral nervous system as physiological regulators and as protective agents for acquired or inherited peripheral neuropathy. In recent years, modulation of neuroactive steroids levels has been studied as a potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd7c605c6609bf5982f9fe28a6f4bd1
https://doi.org/10.1523/jneurosci.1898-10.2010

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Inhibition of NF- κ B Activity by Minor Polar Components of Extra-Virgin Olive Oil at Gastric Level

Autor: Marco Fumagalli, Elisa Colombo, Enrico Sangiovanni, Federico Abbiati, Mario Dell'Agli, Donatella Caruso

Publikováno v: Phytotherapy Research. 26:1569-1571

The present work evaluates the effect of olive oil phenols on NF-κB activity in human gastric adenocarcinoma cells. The total phenol content was measured by the Folin Ciocalteu method, whereas the composition was assessed by LC-MS/MS analysis. Secoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a82adf4ebf35ffd3b41dff0cb3f9935c
https://doi.org/10.1002/ptr.4600

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Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma

Autor: Silvia Giatti, Simone Romano, Donatella Caruso, Letizia Fusco, Guido Cavaletti, Federico Abbiati, Roberto Cosimo Melcangi

Publikováno v: The Journal of steroid biochemistry and molecular biology. 146

Observations performed in a subset of patients treated for male pattern hair loss indicate that persistent sexual side effects as well as anxious/depressive symptomatology have been reported even after discontinuation of finasteride treatment. Due to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331be0bbd3a9fcbb40f7bace39c177cc
https://pubmed.ncbi.nlm.nih.gov/24717976

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