Zobrazeno 1 - 10
of 371
pro vyhledávání: '"Federico, Turkheimer"'
Autor:
Tracy Butler, Julia Schubert, Nikolaos A. Karakatsanis, Xiuyuan Hugh Wang, Ke Xi, Yeona Kang, Kewei Chen, Liangdong Zhou, Edward K. Fung, Abigail Patchell, Abhishek Jaywant, Yi Li, Gloria Chiang, Lidia Glodzik, Henry Rusinek, Mony de Leon, Federico Turkheimer, Sudhin A. Shah
Publikováno v:
Neurotrauma Reports, Vol 5, Iss 1, Pp 359-366 (2024)
Brain fluid clearance by pathways including the recently described paravascular glymphatic system is a critical homeostatic mechanism by which metabolic products, toxins, and other wastes are removed from the brain. Brain fluid clearance may be espec
Externí odkaz:
https://doaj.org/article/416f7eb348bb4d079b21ecc32ecb50a0
Autor:
Oliver Cousins, Julia J. Schubert, Avinash Chandra, Mattia Veronese, Polena Valkimadi, Byron Creese, Zunera Khan, Ryan Arathimos, Adam Hampshire, Ivana Rosenzweig, Clive Ballard, Anne Corbett, Dag Aasland, Latha Velayudhan, Michael O’Neill, David Collier, Ramla Awais, Kerstin Sander, Erik Årstad, Oliver Howes, Federico Turkheimer, Angela Hodges
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background Microglia are increasingly understood to play an important role in the pathogenesis of Alzheimer’s disease. The rs75932628 (p.R47H) TREM2 variant is a well-established risk factor for Alzheimer’s disease. TREM2 is a microglial
Externí odkaz:
https://doaj.org/article/dcda124d1d09457494573f17556489a7
Autor:
Ottavia Dipasquale, Alexander Cohen, Daniel Martins, Fernando Zelaya, Federico Turkheimer, Mattia Veronese, Mitul A. Mehta, Steven C. R. Williams, Baolian Yang, Suchandrima Banerjee, Yang Wang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Receptor-enriched analysis of functional connectivity by targets (REACT) is a strategy to enrich functional MRI (fMRI) data with molecular information on the neurotransmitter distribution density in the human brain, providing a biological ba
Externí odkaz:
https://doaj.org/article/573018b0c58447aab26e4d8fb1c3acf5
Autor:
Sameer Jauhar, Robert A. McCutcheon, Mattia Veronese, Faith Borgan, Matthew Nour, Maria Rogdaki, Fiona Pepper, James M. Stone, Alice Egerton, George Vamvakas, Federico Turkheimer, Philip K. McGuire, Oliver D. Howes
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The neuromodulator dopamine and excitatory neurotransmitter glutamate have both been implicated in the pathogenesis of psychosis, and dopamine antagonists remain the predominant treatment for psychotic disorders. To date no study has measure
Externí odkaz:
https://doaj.org/article/8dd3d6e9caa94fe18290de30b46752d7
Autor:
Marta Vicente-Rodríguez, Renzo Mancuso, Alba Peris-Yague, Camilla Simmons, NIMA Consortium, Diego Gómez-Nicola, V. Hugh Perry, Federico Turkheimer, Simon Lovestone, Christine A. Parker, Diana Cash
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Neuroinflammation is an important component of many neurodegenerative diseases, whether as a primary cause or a secondary outcome. For that reason, either as diagnostic tools or to monitor progression and/or pharmacological interventions, th
Externí odkaz:
https://doaj.org/article/b170cf7515074d439babacd3d3763def
Autor:
Alexander Gerhard, Richard Sharples, Tsepo Goerttler, Kathryn McDonald, Eszter Visi, Rainer Hinz, Federico Turkheimer, Isabel Lewzey, Karl Herholz, Andreas H. Jacobs, Clive Holmes
Publikováno v:
Exploration of Neuroscience, Vol 2, Iss 2, Pp 52-66 (2023)
Aim: Microglial activation is increasingly recognised as a factor in the progression of Alzheimer’s disease (AD) and may be modified by systemic inflammatory signals including serum tumour necrosis factor (TNF)-α. The aim was to investigate whethe
Externí odkaz:
https://doaj.org/article/8e7485364cb346a99bb854966d873498
Autor:
Manfred G Kitzbichler, Daniel Martins, Richard AI Bethlehem, Richard Dear, Rafael Romero-Garcia, Varun Warrier, Jakob Seidlitz, Ottavia Dipasquale, Federico Turkheimer, Mara Cercignani, Edward T Bullmore, Neil A Harrison
Publikováno v:
eLife, Vol 12 (2023)
The relationship between obesity and human brain structure is incompletely understood. Using diffusion-weighted MRI from ∼30,000 UK Biobank participants, we test the hypothesis that obesity (waist-to-hip ratio, WHR) is associated with regional diff
Externí odkaz:
https://doaj.org/article/43ef9701f5bf4bff98d32301f2f057fc
Autor:
Margherita Tassan Mazzocco, Valentina Murtaj, Daniel Martins, Roberta Schellino, Angela Coliva, Elisa Toninelli, Alessandro Vercelli, Federico Turkheimer, Sara Belloli, Rosa Maria Moresco
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background One intrastriatal administration of quinolinic acid (QA) in rats induces a lesion with features resembling those observed in Huntington’s disease. Our aim is to evaluate the effects of the cysteinyl leukotriene receptor antagoni
Externí odkaz:
https://doaj.org/article/974ef2f31bcc4b358530cb0116958ea0
Autor:
Andrea Arighi, Marina Arcaro, Giorgio Giulio Fumagalli, Tiziana Carandini, Anna Margherita Pietroboni, Luca Sacchi, Chiara Fenoglio, Maria Serpente, Federica Sorrentino, Giovanni Isgrò, Federico Turkheimer, Elio Scarpini, Daniela Galimberti
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Aquaporin-4 (AQP4) is a channel protein that plays a fundamental role in glymphatic system, a newly described pathway for fluid exchange in the central nervous system, as well as a central figure in a fascinating new theory for the pathophys
Externí odkaz:
https://doaj.org/article/9ba949bf23884ea38e448450ec33ba25
Autor:
Jessica Dafflon, Pedro F. Da Costa, František Váša, Ricardo Pio Monti, Danilo Bzdok, Peter J. Hellyer, Federico Turkheimer, Jonathan Smallwood, Emily Jones, Robert Leech
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Most neuroimaging studies are associated with a broad range analytic and methodological choices that the researcher needs to make, but every choice might lead to different answers, and evaluating all possible analytic choices is computationally chall
Externí odkaz:
https://doaj.org/article/d2239651407d46d1b4d3c392ebc0faed