Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Federico, Fogolari"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract This study presents a comprehensive analysis of the cholesterol binding mechanism and conformational changes in cyclodextrin (CD) carriers, namely βCD, 2HPβCD, and MβCD. The results revealed that the binding of cholesterol to CDs was spon
Externí odkaz:
https://doaj.org/article/e5bc523da2ac419bbfdc3a1cc7264eb4
Autor:
Gennaro Esposito, Yamanappa Hunashal, Mathias Percipalle, Federico Fogolari, Tomas Venit, Ainars Leonchiks, Kristin C Gunsalus, Fabio Piano, Piergiorgio Percipalle
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303839 (2024)
The interaction between SARS-CoV-2 non-structural protein Nsp9 and the nanobody 2NSP90 was investigated by NMR spectroscopy using the paramagnetic perturbation methodology PENELOP (Paramagnetic Equilibrium vs Nonequilibrium magnetization Enhancement
Externí odkaz:
https://doaj.org/article/a0e1d5066c4b437da54641185d876771
Publikováno v:
Biophysica, Vol 2, Iss 4, Pp 340-352 (2022)
Entropy of multivariate distributions may be estimated based on the distances of nearest neighbours from each sample from a statistical ensemble. This technique has been applied on biomolecular systems for estimating both conformational and translati
Externí odkaz:
https://doaj.org/article/0cf92b7e7cc542aa9f05cea92dbbce81
Autor:
Federico Fogolari, Gennaro Esposito
Publikováno v:
Biophysica, Vol 1, Iss 3, Pp 279-296 (2021)
Estimation of solvent entropy from equilibrium molecular dynamics simulations is a long-standing problem in statistical mechanics. In recent years, methods that estimate entropy using k-th nearest neighbours (kNN) have been applied to internal degree
Externí odkaz:
https://doaj.org/article/80adcb001b3049cc9a420e0e9b95e505
Autor:
Catia Mio, Nadia Passon, Federico Fogolari, Claudia Cesario, Antonio Novelli, Carla Pittini, Giuseppe Damante
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 9, Iss 9, Pp n/a-n/a (2021)
Abstract Background Cornelia de Lange syndrome (CdLS) is a rare and clinically variable syndrome characterized by growth impairment, multi‐organ anomalies, and a typical set of facial dysmorphisms. Here we describe a 2‐year‐old female child har
Externí odkaz:
https://doaj.org/article/971629ff9a734a8e9ec9c3055dad62b3
Autor:
Jessica Garau, Silvia Masnada, Francesca Dragoni, Daisy Sproviero, Federico Fogolari, Stella Gagliardi, Giana Izzo, Costanza Varesio, Simona Orcesi, Pierangelo Veggiotti, Gian Vincenzo Zuccotti, Orietta Pansarasa, Davide Tonduti, Cristina Cereda
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Aicardi–Goutières Syndrome (AGS) is a rare disorder characterized by neurological and immunological signs. In this study we have described a child with a phenotype consistent with AGS carrying a novel compound heterozygous mutation in RNASEH2B gen
Externí odkaz:
https://doaj.org/article/bfb8e9e1e61240c6ac4979c64f0ecdd5
Autor:
Catia Mio, Federico Fogolari, Laura Pezzoli, Angela V. D’Elia, Maria Iascone, Giuseppe Damante
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 7, Pp n/a-n/a (2020)
Abstract Background The Bosch‐Boonstra‐Schaaf optic atrophy syndrome (BBSOAS) is an autosomal‐dominant disorder (OMIM615722) mostly characterized by optic atrophy and/or hypoplasia, mild intellectual disability, hypotonia, seizures/infantile ep
Externí odkaz:
https://doaj.org/article/366ddf04f33c48069963929cac8c1c34
Autor:
Federico Fogolari, Giuseppe Serra, Saida Saad Mohamed Mahmoud, Beatrice Portelli, Giovanni D'Agostino, Gianluca Pollastri
Publikováno v:
Current Bioinformatics. 18
Background: Over the last several decades, predicting protein structures from amino acid sequences has been a core task in bioinformatics. Nowadays, the most successful methods employ multiple sequence alignments and can predict the structure with ex
Publikováno v:
Molecules, Vol 26, Iss 12, p 3567 (2021)
Background: Nanobodies, or VHHs, are derived from heavy chain-only antibodies (hcAbs) found in camelids. They overcome some of the inherent limitations of monoclonal antibodies (mAbs) and derivatives thereof, due to their smaller molecular size and h
Externí odkaz:
https://doaj.org/article/3a448972d2c1403ab2a2f3e9d28701aa
Autor:
Yamanappa Hunashal, Cristina Cantarutti, Sofia Giorgetti, Loredana Marchese, Federico Fogolari, Gennaro Esposito
Publikováno v:
Molecules, Vol 25, Iss 21, p 5187 (2020)
Background: The interaction between proteins and nanoparticles is a very relevant subject because of the potential applications in medicine and material science in general. Further interest derives from the amyloidogenic character of the considered p
Externí odkaz:
https://doaj.org/article/c07d3cc2588348b3af1c2ab9b838e43d