Development and Validation of a GC-MS Method for the Detection and Quantification of Clotiapine in Blood and Urine Specimens and Application to a Postmortem Case

Autor: Giulio Mannocchi, Flaminia Pantano, Roberta Tittarelli, Miriam Catanese, Federica Umani Ronchi, Francesco Paolo Busardò

Publikováno v: International Journal of Analytical Chemistry, Vol 2015 (2015)

Introduction. Clotiapine is an atypical antipsychotic of the dibenzothiazepine class introduced in a few European countries since 1970, efficient in treatment-resistant schizophrenic patients. There is little published data on the therapeutic and tox

Externí odkaz: https://doaj.org/article/6c6be7f0d8e44a638667540f7ffde43f

Evidence of Natural GHB Presence in Energy Drinks: Caution in Data Interpretation in Suspected DFSA Cases

Autor: Fabio Vaiano, Federica Umani Ronchi

Publikováno v: Journal of Analytical Toxicology. 44:811-817

Gamma-hydroxybutyric acid (GHB), usually reported as rape drug in drug-facilitated sexual assaults (DFSA), is an endogenous substance in human body and is also found in many beverages. This may lead to data misinterpretation in forensic cases. Herein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96cc14c5232116826f2d3ffc5aec00cd
https://doi.org/10.1093/jat/bkaa025

A novel LC–MS/MS analytical method for detection of articaine and mepivacaine in blood and its application to a preliminary pharmacokinetic study

Autor: Federica Umani Ronchi, Alice Ciolini, Francesco Mari, Antonina Argo, Elisabetta Bertol, Chiara Capretti, S Zerbo, Fabio Vaiano

Local anaesthetics (LAs) are commonly used in surgery, especially in dentistry. They cause a transitory inhibition of nerve signal due to the blockade of the voltage-gated sodium channels. LAs are administrated alone or with vasoconstriction agents,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f907b950b394cebe112df9959890efb
http://hdl.handle.net/11573/1497181

CRISPR-Cas and its wide-ranging applications: from human genome editing to environmental implications, technical limitations, hazards and bioethical issues

Autor: Alessandro Del Rio, Simona Zaami, Federica Umani Ronchi, Fabrizio Signore, Enrico Marinelli, Roberto Piergentili

Publikováno v: Cells, Vol 10, Iss 969, p 969 (2021)
Cells
Cells 10 (2021). doi:10.3390/cells10050969
info:cnr-pdr/source/autori:Roberto Piergentili, Alessandro Del Rio, Fabrizio Signore, Federica Umani Ronchi, Enrico Marinelli and Simona Zaami/titolo:CRISPR-Cas and Its Wide-Ranging Applications: From Human Genome Editing to Environmental Implications, Technical Limitations, Hazards and Bioethical Issues/doi:10.3390%2Fcells10050969/rivista:Cells/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:10

The CRISPR-Cas system is a powerful tool for in vivo editing the genome of most organisms, including man. During the years this technique has been applied in several fields, such as agriculture for crop upgrade and breeding including the creation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f5a49ba183c150efa32fd41c88fe8f
http://hdl.handle.net/11573/1545241

Psychotropic substance abuse and fitness to hold a driving license in Italy

Autor: Diego Palumbo, Jennifer P. Pascali, Elisabetta Bertol, Fabio Vaiano, Federica Umani Ronchi, Francesco Mari

Objective: Driving under the influence (DUI) of psychotropic substances is a serious and widespread problem in road safety. All countries try to reduce the impact with legislative controls over the criteria to regain a driver's license after suspensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c88ace9f48d85aaf85967c9bb16c333
http://hdl.handle.net/11573/1339434