Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Federica Storti"'
Autor:
M. Elizabeth Hartnett, MD, Ward Fickweiler, MD, PhD, Anthony P. Adamis, MD, Michael Brownlee, MD, Arup Das, MD, PhD, Elia J. Duh, MD, Edward P. Feener, PhD, George King, MD, Renu Kowluru, PhD, Ulrich F.O. Luhmann, PhD, Federica Storti, PhD, Charles C. Wykoff, MD, PhD, Lloyd Paul Aiello, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 5, Pp 100521- (2024)
Purpose: Hyperglycemia is a major risk factor for early lesions of diabetic retinal disease (DRD). Updating the DRD staging system to incorporate relevant basic and cellular mechanisms pertinent to DRD is necessary to better address early disease, di
Externí odkaz:
https://doaj.org/article/d168a05b499a4366a82cce9f5b9f8421
Autor:
Ilaria M.C. Orlando, Véronique N. Lafleur, Federica Storti, Patrick Spielmann, Lisa Crowther, Sara Santambrogio, Johannes Schödel, David Hoogewijs, David R. Mole, Roland H. Wenger
Publikováno v:
Haematologica, Vol 105, Iss 12 (2019)
While it is well-established that distal hypoxia response elements (HREs) regulate hypoxia-inducible factor (HIF) target genes such as erythropoietin (Epo), an interplay between multiple distal and proximal (promoter) HREs has not been described so f
Externí odkaz:
https://doaj.org/article/f666788e99d749ae888feb90ab218e22
Autor:
Federica Storti, Katrin Klee, Vyara Todorova, Regula Steiner, Alaa Othman, Saskia van der Velde-Visser, Marijana Samardzija, Isabelle Meneau, Maya Barben, Duygu Karademir, Valda Pauzuolyte, Sanford L Boye, Frank Blaser, Christoph Ullmer, Joshua L Dunaief, Thorsten Hornemann, Lucia Rohrer, Anneke den Hollander, Arnold von Eckardstein, Jürgen Fingerle, Cyrille Maugeais, Christian Grimm
Publikováno v:
eLife, Vol 8 (2019)
Age-related macular degeneration (AMD) is a progressive disease of the retinal pigment epithelium (RPE) and the retina leading to loss of central vision. Polymorphisms in genes involved in lipid metabolism, including the ATP-binding cassette transpor
Externí odkaz:
https://doaj.org/article/992b60ec1c9e471eb4c01c575ad91eb9
Autor:
Federica Storti, Sara Santambrogio, Lisa M. Crowther, Teresa Otto, Irene Abreu-Rodríguez, Muriel Kaufmann, Cheng-Jun Hu, Christof Dame, Joachim Fandrey, Roland H. Wenger, David Hoogewijs
Publikováno v:
Haematologica, Vol 99, Iss 4 (2014)
Externí odkaz:
https://doaj.org/article/8d88a7c6107a4cf3bc6dc172a624b2da
Autor:
Charline Ladroue, David Hoogewijs, Sophie Gad, Romain Carcenac, Federica Storti, Michel Barrois, Anne-Paule Gimenez-Roqueplo, Michel Leporrier, Nicole Casadevall, Olivier Hermine, Jean-Jacques Kiladjian, André Baruchel, Fadi Fakhoury, Brigitte Bressac-de Paillerets, Jean Feunteun, Nathalie Mazure, Jacques Pouysségur, Roland H. Wenger, Stéphane Richard, Betty Gardie
Publikováno v:
Haematologica, Vol 97, Iss 1 (2012)
Background Congenital secondary erythrocytoses are due to deregulation of hypoxia inducible factor resulting in overproduction of erythropoietin. The most common germline mutation identified in the hypoxia signaling pathway is the Arginine 200-Trypto
Externí odkaz:
https://doaj.org/article/10d5cbd37645421ea450e12673c5f481
Publikováno v:
Translational Vision Science & Technology
Inflammation and endothelial activation play a pivotal role in development and progression of diabetic retinopathy (DR), a vision-threatening complication of diabetes mellitus (DM) and the leading cause of blindness in the working age population. Eas
Autor:
David R. Mole, Roland H. Wenger, Lisa Crowther, David Hoogewijs, Ilaria M.C. Orlando, Patrick Spielmann, Federica Storti, Sara Santambrogio, Johannes Schödel, Véronique N. Lafleur
Publikováno v:
Haematologica
While it is well-established that distal hypoxia response elements (HREs) regulate hypoxia-inducible factor (HIF) target genes such as erythropoietin (Epo), an interplay between multiple distal and proximal (promoter) HREs has not been described so f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1444796cf1cdd6eceafe64a52ab01f
https://doi.org/10.3324/haematol.2019.236406
https://doi.org/10.3324/haematol.2019.236406
Autor:
Federica, Storti, Christian, Grimm
Publikováno v:
Advances in experimental medicine and biology. 1185
The importance of cholesterol as a structural component of photoreceptors and the association between impaired cholesterol homeostasis and age-related macular degeneration (AMD) prompted in the last years a deep investigation of its metabolism in the
Autor:
Katrin Klee, Frank Blaser, Marijana Samardzija, Daniel Barthelmes, Isabelle Meneau, Federica Storti, Christian Schori, Maya Barben, Martin Biel, Christian Grimm, Stylianos Michalakis, Divya Ail
Publikováno v:
Cell Death and Differentiation
Reduced choroidal blood flow and tissue changes in the ageing human eye impair oxygen delivery to photoreceptors and the retinal pigment epithelium. As a consequence, mild but chronic hypoxia may develop and disturb cell metabolism, function and ulti
Autor:
Ema Ozaki, Sofia Theodoropoulou, Matthew Campbell, Akeem Browne, Federica Storti, Erin Fahey, Chris H. Greene, Shervin Liddie, Alan Hopkins, Mark Cahill, Marian M. Humphries, Eleanor Demmons, Paul F. Kenna, Christian Grimm, Sarah L. Doyle, Anne M. Curtis, Matthew S. Lawrence, Peter Humphries, Lucia Celkova, Natalie Hudson
Publikováno v:
Hudson, N, Celkova, L, Hopkins, A, Greene, C, Storti, F, Ozaki, E, Fahey, E, Theodoropoulou, S, Kenna, P F, Humphries, M M, Curtis, A M, Demmons, E, Browne, A, Liddie, S, Lawrence, M S, Grimm, C, Cahill, M T, Humphries, P, Doyle, S L & Campbell, M 2019, ' Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy ', JCI Insight, vol. 4, no. 15, 130273 . https://doi.org/10.1172/jci.insight.130273
Age-related macular degeneration (AMD) is the leading cause of central retinal vision loss worldwide, with an estimated 1 in 10 people over the age of 55 showing early signs of the condition. There are currently no forms of therapy available for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6e73e0d8f14543916d8e047e70781b
https://europepmc.org/articles/PMC6693834/
https://europepmc.org/articles/PMC6693834/