Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Federica Rapetti"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8052 (2024)
Phosphodiesterase 4 (PDE4) enzymes catalyze cyclic adenosine monophosphate (cAMP) hydrolysis and are involved in a variety of physiological processes, including brain function, monocyte and macrophage activation, and neutrophil infiltration. Among di
Externí odkaz:
https://doaj.org/article/47f814546bba4471b143d5bb50bd7780
Autor:
Federica Rapetti, Andrea Spallarossa, Eleonora Russo, Debora Caviglia, Carla Villa, Bruno Tasso, Maria Grazia Signorello, Camillo Rosano, Erika Iervasi, Marco Ponassi, Chiara Brullo
Publikováno v:
Molecules, Vol 29, Iss 10, p 2298 (2024)
To further extend the structure-activity relationships (SARs) of 5-aminopyrazoles (5APs) and identify novel compounds able to interfere with inflammation, oxidative stress, and tumorigenesis, 5APs 1–4 have been designed and prepared. Some chemical
Externí odkaz:
https://doaj.org/article/f972d7ba951b4953b48e4c2552e77869
Autor:
Maria Grazia Signorello, Federica Rapetti, Elda Meta, Adama Sidibè, Olga Bruno, Chiara Brullo
Publikováno v:
Molecules, Vol 26, Iss 19, p 5735 (2021)
(1) Background: different previously synthesized pyrazoles and imidazo-pyrazoles showed interesting anti-angiogenic action, being able to interfere with ERK1/2, AKT and p38MAPK phosphorylation in different manners and with different potency; (2) Meth
Externí odkaz:
https://doaj.org/article/345dea1b67ce44819c53d6fad349c480
Publikováno v:
Molecules, Vol 25, Iss 15, p 3457 (2020)
The pyrazole nucleus has long been known as a privileged scaffold in the synthesis of biologically active compounds. Within the numerous pyrazole derivatives developed as potential drugs, this review is focused on molecules characterized by a urea fu
Externí odkaz:
https://doaj.org/article/1d8acc78109a424cb701f37f7024f8f4
Autor:
Valeria Cavalloro, Katia Russo, Francesca Vasile, Luca Pignataro, Archimede Torretta, Stefano Donini, Marta S. Semrau, Paola Storici, Daniela Rossi, Federica Rapetti, Chiara Brullo, Emilio Parisini, Olga Bruno, Simona Collina
Publikováno v:
Molecules, Vol 25, Iss 4, p 935 (2020)
Alzheimer’s disease is the most common type of dementia, affecting millions of people worldwide. One of its main consequences is memory loss, which is related to downstream effectors of cyclic adenosine monophosphate (cAMP). A well-established stra
Externí odkaz:
https://doaj.org/article/39f2c7f5d6a844c197431cc422bb7ef5
Autor:
Chiara Brullo, Matteo Massa, Federica Rapetti, Silvana Alfei, Maria B. Bertolotto, Fabrizio Montecucco, Maria Grazia Signorello, Olga Bruno
Publikováno v:
Molecules, Vol 25, Iss 4, p 899 (2020)
Several anti-inflammatory agents based on pyrazole and imidazopyrazole scaffolds and a large library of substituted catechol PDE4D inhibitors were reported by us in the recent past. To obtain new molecules potentially able to act on different targets
Externí odkaz:
https://doaj.org/article/e7c6db4d1b4f4eabb71ca1df7b4c98b6
Autor:
Valeria Cavalloro, Marta Rui, Giacomo Rossino, Daniela Rossi, Federica Rapetti, Chiara Brullo, Olga Bruno, Simona Collina
Publikováno v:
Proceedings, Vol 22, Iss 1, p 15 (2019)
Nowadays, the incidence of neurodegenerative diseases is increasing, and these disorders will become one of the main challenges for medicine and public health in future years. Particularly, memory loss characterizes many neurodegenerative pathologies
Externí odkaz:
https://doaj.org/article/c57217bcf2314546974088bf34cb8d3e
Autor:
Elena Cichero, Federica Rapetti, Matteo Lusardi, Naomi Scarano, Silvana Alfei, Paola Altieri, Silvano Garibaldi, Pietro Ameri, Maria Grazia Signorello, Chiara Brullo
Publikováno v:
ChemMedChem. 18
Autor:
Federica Rapetti, Francesca Vasile, Katia Russo, Daniela Rossi, Chiara Brullo, Paola Storici, Archimede Torretta, Simona Collina, Marta S. Semrau, Stefano Donini, Emilio Parisini, Luca Pignataro, Valeria Cavalloro, Olga Bruno
Publikováno v:
Molecules
Volume 25
Issue 4
Molecules, Vol 25, Iss 4, p 935 (2020)
Volume 25
Issue 4
Molecules, Vol 25, Iss 4, p 935 (2020)
Alzheimer&rsquo
s disease is the most common type of dementia, affecting millions of people worldwide. One of its main consequences is memory loss, which is related to downstream effectors of cyclic adenosine monophosphate (cAMP). A well-establi
s disease is the most common type of dementia, affecting millions of people worldwide. One of its main consequences is memory loss, which is related to downstream effectors of cyclic adenosine monophosphate (cAMP). A well-establi
Autor:
Federica Rapetti, Camillo Rosano, Olga Bruno, Chiara Brullo, Irena Maric, Marina Mapelli, Silvana Alfei, Francesca Rizzelli, Maurizio Viale
Even though immunotherapy has radically changed the search for anticancer therapies, there are still many different pathways that are open to intervention with traditional small molecules. To expand our investigation in the anticancer field, we repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed80ba5fe42f00d603178056d7a681ab
http://hdl.handle.net/11567/1019894
http://hdl.handle.net/11567/1019894