Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Federica Raimondi"'
Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements
Autor:
Federica Raimondi, Kah Mun Siow, Dominik Wrona, Carla Fuster-García, Oleksandr Pastukhov, Michael Schmitz, Katja Bargsten, Lucas Kissling, Daan C. Swarts, Geoffroy Andrieux, Toni Cathomen, Ute Modlich, Martin Jinek, Ulrich Siler, Janine Reichenbach
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract CRISPR-based genome editing of pseudogene-associated disorders, such as p47 phox -deficient chronic granulomatous disease (p47 CGD), is challenged by chromosomal rearrangements due to presence of multiple targets. We report that interactions
Externí odkaz:
https://doaj.org/article/93b02712c21d4f31ac658ae71b0f19f4
Autor:
Dominik Wrona, Oleksandr Pastukhov, Robert S. Pritchard, Federica Raimondi, Joëlle Tchinda, Martin Jinek, Ulrich Siler, Janine Reichenbach
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 936-943 (2020)
Resurrection of non-processed pseudogenes may increase the efficacy of therapeutic gene editing, upon simultaneous targeting of a mutated gene and its highly homologous pseudogenes. To investigate the potency of this approach for clinical gene therap
Externí odkaz:
https://doaj.org/article/42bafebc22c442c88606cfeb4729624c
Autor:
Federica Raimondi, Ulrich Siler, Oleksandr Pastukhov, Robert S. Pritchard, Joelle Tchinda, Martin Jinek, Janine Reichenbach, Dominik Wrona
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 936-943 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Resurrection of non-processed pseudogenes may increase the efficacy of therapeutic gene editing, upon simultaneous targeting of a mutated gene and its highly homologous pseudogenes. To investigate the potency of this approach for clinical gene therap
We are interested in a reduced model for corrosion of iron, in which ferric cations and electrons evolve in a fixed oxide layer subject to a self-consistent electrostatic potential. Reactions at the boundaries are modeled thanks to Butler-Volmer form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183597d0c0103affd2153b72abfbdcaa
https://hal.science/hal-03549457
https://hal.science/hal-03549457
Autor:
Federica Raimondi
Publikováno v:
Asymptotic Analysis
Asymptotic Analysis, 2022, ⟨10.3233/ASY-221783⟩
Asymptotic Analysis, 2022, ⟨10.3233/ASY-221783⟩
This paper deals with the homogenization of a quasilinear elliptic problem having a singular lower order term and posed in a two-component domain with an ε-periodic imperfect interface. We prescribe a Dirichlet condition on the exterior boundary, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec405f235b7f6ae8ab3d7e8308f57995
https://hal.archives-ouvertes.fr/hal-03512624
https://hal.archives-ouvertes.fr/hal-03512624
Autor:
Federica Raimondi, Patrizia Donato
Publikováno v:
Journal of Elliptic and Parabolic Equations
Journal of Elliptic and Parabolic Equations, 2019
Journal of Elliptic and Parabolic Equations, 2019
In this work we prove a uniqueness result for a quasilinear singular elliptic problem posed in a two-component domain. We prescribe a Dirichlet condition on the exterior boundary, while we prescribe a continuous flux and a jump of the solution propor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c46ef8652dff3fe82f3528539449c5
https://hal.archives-ouvertes.fr/hal-02381429
https://hal.archives-ouvertes.fr/hal-02381429
Publikováno v:
Nonlinear Analysis: Theory, Methods and Applications
Nonlinear Analysis: Theory, Methods and Applications, Elsevier, 2018
Nonlinear Analysis: Theory, Methods and Applications, Elsevier, 2018
In this work we study the asymptotic behavior of a class of quasilinear elliptic problems posed in a domain perforated by e -periodic holes of size e . The quasilinear equations present a nonlinear singular lower order term f ζ ( u e ) , where u e i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700db5a99228231aa0004371cb3b4f7c
https://hal.archives-ouvertes.fr/hal-02381360
https://hal.archives-ouvertes.fr/hal-02381360
Publikováno v:
Ricerche di matematica
Ricerche di matematica, Springer Verlag, 2017
Ricerche di matematica, Springer Verlag, 2017
In this paper we prove some existence, uniqueness and regularity results for a weak solution of a quasilinear elliptic nonlinear problem posed in a domain perforated by one or more holes. The nonlinear term is of the form $$f\zeta (u)$$ , where $$\ze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e936f732d679424349149af48093561
https://hal.archives-ouvertes.fr/hal-02381320
https://hal.archives-ouvertes.fr/hal-02381320
Autor:
Patrizia Donato, Federica Raimondi
Publikováno v:
Constanda C., Dalla Riva M., Lamberti P., Musolino P.(eds) Integral Methods in Science and Engineering, Volume 1
Constanda C., Dalla Riva M., Lamberti P., Musolino P.(eds) Integral Methods in Science and Engineering, Volume 1, 2017
Integral Methods in Science and Engineering, Volume 1 ISBN: 9783319593838
Constanda C., Dalla Riva M., Lamberti P., Musolino P.(eds) Integral Methods in Science and Engineering, Volume 1, 2017
Integral Methods in Science and Engineering, Volume 1 ISBN: 9783319593838
We prove here some existence, uniqueness, and regularity results for a weak solution of a quasilinear elliptic singular problem posed in a two-component domain. The difficulty arises in dealing simultaneously with the quasilinear matrix field, the si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2832f4d669560d6caaa688397b4379ce
https://hal.archives-ouvertes.fr/hal-02381350
https://hal.archives-ouvertes.fr/hal-02381350
Autor:
Guido Jacopo Massei, Paola Rucci, Gabriele Massei, Marta Milianti, Giovanni B. Cassano, Alfredo Sbrana, Francesca Milani, Chiara Gonnelli, Laura Ravani, Mario Miniati, Jacopo V. Bizzarri, Federica Raimondi
The aim of this article is to examine the onset and clinical correlates of substance use in patients with psychotic disorders. One hundred and eight inpatients and outpatients with DSM-IV psychotic disorders were evaluated with the SCI-SUBS, an instr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b224f6390d3f91aa469d3994a22a21
http://hdl.handle.net/11585/120785
http://hdl.handle.net/11585/120785