Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Federica Pimpinelli"'
Autor:
Elio Messi, Valentina Andre, Cecilia Gotti, Roberto Maggi, Chiara Rigobello, Federica Pimpinelli
Publikováno v:
Molecular and cellular endocrinology. 460
The activation of nicotinic cholinergic receptors (nAChR) inhibits the reproductive axis; however, it is not clear whether nicotine may directly modulate the release of hypothalamic gonadotropin-releasing hormone (GnRH). Experiments carried out in GT
Autor:
Roberto Maggi, Tomas Hökfelt, Marco Parenti, Federica Pimpinelli, Francesca Guzzi, Flavio Piva
Publikováno v:
Brain Research. 1070:15-23
Opioid peptides exert an inhibitory effect on hypothalamic gonadotropin releasing hormone (GnRH) secretion mainly by interacting with μ-opioid receptors. Although a direct role for opioids via δ-opioid receptors (DORs) has been suggested, the prese
Autor:
Sophia Colamarino, Roberta Zaninetti, Elena I. Rugarli, M. Piccolella, Cristiano Rumio, Flavio Piva, Roberto Maggi, Anna Cariboni, Federica Pimpinelli
Publikováno v:
Human Molecular Genetics. 13:2781-2791
X-linked Kallmann's syndrome (KS) is a genetic disease characterized by anosmia and hypogonadism due to impairment in the development of olfactory axons and in the migration of gonadotropin-releasing hormone (GnRH)-producing neurons. Deletions or poi
Publikováno v:
Neuroendocrinology. 69:54-62
Estrogens modulate the density of opioid receptors in selected brain areas; however, it is not clear whether they exert such an effect directly on the cells which express the opioid receptors. Therefore, we analyzed the binding of [3H]-diprenorphine
Publikováno v:
Endocrinology. 140:171-177
PGs of the E series are involved in the control of LHRH secretion. The present experiments were conducted to clarify whether PGI2 (prostacyclin) might be also involved in such a control, using multiple methodological approaches on immortalized LHRH-s
Publikováno v:
Brain Research. 798:75-82
Neuropeptide Y (NPY) participates in the control of several functions in the nervous system. NPYergic neurons present in brain areas involved in cognitive processes are linked to ascending projections of the cholinergic system, a finding that suggest
Publikováno v:
Endocrinology. 136:5177-5181
The endogenous opioids play a major role in regulation of the secretion of hypothalamic LHRH. However, it is not clear whether opioids exert a direct effect on LHRH neurons or interfere with other neuronal systems impinging on the cells synthesizing
Publikováno v:
Università degli Studi di Milano-IRIS
Recent evidence suggests a direct antiproliferative effect of LHRH agonists on the prostatic carcinoma cell line LNCaP. In the present study the possible presence of a LHRH degrading activity (LHRH-DA) in soluble fractions of LNCaP cell homogenates h
Autor:
Roberta M. Moretti, Federica Pimpinelli, Donatella Dondi, Patrizia Limonta, Marcella Motta, Marina Montagnani, Roberto Maggi
Publikováno v:
The Prostate. 23:315-328
Recent evidence supports the hypothesis of a direct action of LHRH at the level of the prostate. Since peptidases able to degrade the hormone are present in several LHRH target structures, it was deemed of interest to investigate whether the prostate
Publikováno v:
The European journal of neuroscience. 21(8)
Transmissible prion diseases are fatal neurodegenerative diseases associated with the conversion of the normal host prion protein (PrP c) into an abnormal isoform (PrP Sc) that accumulates in brain. This pathology affects neurons of the central nervo