Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Federica Pezzimenti"'
Autor:
Lucia Falbo, Hervé Técher, Vincenzo Sannino, Michela Robusto, Giovanni Fagà, Federica Pezzimenti, Francesco Romeo, Luca Gabriele Colombo, Stefania Vultaggio, Daniele Fancelli, Silvia Monzani, Valentina Cecatiello, Sebastiano Pasqualato, Mario Varasi, Ciro Mercurio, Vincenzo Costanzo
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110567- (2024)
Summary: Replication origin assembly is a pivotal step in chromosomal DNA replication. In this process, the ORC complex binds DNA and, together with the CDC6 and CDT1, promotes the loading of the MCM helicase. Chemicals targeting origin assembly migh
Externí odkaz:
https://doaj.org/article/adb2579a538741ef9e88a77c7a491485
Autor:
Lucia Falbo, Erica Raspelli, Francesco Romeo, Simona Fiorani, Federica Pezzimenti, Francesca Casagrande, Ilaria Costa, Dario Parazzoli, Vincenzo Costanzo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
During embryonic development, it is vital to maintain rapid genome duplication. Here, the authors shed light on the mechanism by revealing that SSRP1 stimulates replication origin assembly on somatic nuclei in Xenopus laevis egg extract by promoting
Externí odkaz:
https://doaj.org/article/0d8b5f46cc10411b9cf6cb02f0892298
Autor:
Vincenzo Costanzo, Dario Parazzoli, Francesco Romeo, Lucia Falbo, Erica Raspelli, Francesca Casagrande, Ilaria Costa, Simona Fiorani, Federica Pezzimenti
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
In several metazoans, the number of active replication origins in embryonic nuclei is higher than in somatic ones, ensuring rapid genome duplication during synchronous embryonic cell divisions. High replication origin density can be restored by somat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f82842e0cb87daf336a78223adaafc9
http://link.springer.com/article/10.1038/s41467-020-15180-5
http://link.springer.com/article/10.1038/s41467-020-15180-5
Autor:
Elisa Bernardi, Gianluca Deflorian, Federica Pezzimenti, Victor M Diaz, Marina Mione, Francesco Blasi
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15047 (2010)
Prep1 is a developmentally essential TALE class homeodomain transcription factor. In zebrafish and mouse, Prep1 is already ubiquitously expressed at the earliest stages of development, with important tissue-specific peculiarities. The Prep1 gene in m
Externí odkaz:
https://doaj.org/article/584e3d44d7cd43ee99dacf721b000b5e
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4273 (2009)
PRDM genes are a family of transcriptional regulators that modulate cellular processes such as differentiation, cell growth and apoptosis. Some family members are involved in tissue or organ maturation, and are differentially expressed in specific ph
Externí odkaz:
https://doaj.org/article/ec053a7a2aac4530bb31bc7e0442d672
Publikováno v:
Methods in enzymology. 591
Although many players of the DNA damage response and DNA repair have been identified in several systems their biochemical role is still poorly understood. The use of the Xenopus laevis egg extract cell-free system allowed biochemical dissection of DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6321207b0a7fb4776bbe1133461037f6
https://pubmed.ncbi.nlm.nih.gov/28645370
https://pubmed.ncbi.nlm.nih.gov/28645370
Although many players of the DNA damage response and DNA repair have been identified in several systems their biochemical role is still poorly understood. The use of the Xenopus laevis egg extract cell-free system allowed biochemical dissection of DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::739791362482521d86e9ce348a60fcbf
https://doi.org/10.1016/bs.mie.2017.03.018
https://doi.org/10.1016/bs.mie.2017.03.018
Autor:
Natalia Meani, Elisa Barbieri, Debora Valli, Gianluca Deflorian, Marco Saia, Myriam Alcalay, Federica Pezzimenti, Alicja M. Gruszka
Publikováno v:
Oncotarget
// Elisa Barbieri 1, 4 , Gianluca Deflorian 2 , Federica Pezzimenti 2 , Debora Valli 1 , Marco Saia 1 , Natalia Meani 1 , Alicja M. Gruszka 1, * , Myriam Alcalay 1, 3, * 1 Department of Experimental Oncology, Istituto Europeo di Oncologia, Milan, Ita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c9258fee30c4667074aeb8d5eb6bf46
https://pubmed.ncbi.nlm.nih.gov/27486814
https://pubmed.ncbi.nlm.nih.gov/27486814
Autor:
Federica Pezzimenti, Gianluca Deflorian, Danila Baldessari, Ario de Marco, Marisa Aliprandi, Carlo Beretta, Cristina Santoriello, Mario Cinquanta, Marina Mione, Annunziata Venuto
Publikováno v:
Journal of immunological methods. 346(1-2)
The lack of a sufficient number of antibodies represents an obstacle in the research performed using the zebrafish (Danio rerio) as a model organism. On the other hand, high-throughput generation of antibodies, especially those suitable for immunohis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6ac2fdf31003ef5d1d6fe786923d63
https://pubmed.ncbi.nlm.nih.gov/19410577
https://pubmed.ncbi.nlm.nih.gov/19410577
Autor:
Fabrizio d'Adda di Fagagna, Gianluca Deflorian, Cristina Santoriello, Luisa Lanfrancone, Koichi Kawakami, Marina Mione, Federica Pezzimenti
Publikováno v:
Disease modelsmechanisms. 2(1-2)
SummaryConstitutively active, ‘oncogenic’ H-RAS can drive proliferation and transformation in human cancer, or be a potent inducer of cellular senescence. Moreover, aberrant activation of the Ras pathway owing to germline mutations can cause seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfd23cc08cfcbceedf3c8ac5e425fa2
https://pubmed.ncbi.nlm.nih.gov/19132118
https://pubmed.ncbi.nlm.nih.gov/19132118