Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Federica Moalli"'
Autor:
Federica Colombo, Virginia Guzzeloni, Cise Kizilirmak, Francesca Brambilla, Jose Manuel Garcia-Manteiga, Anna Sofia Tascini, Federica Moalli, Francesca Mercalli, Maurilio Ponzoni, Rosanna Mezzapelle, Marina Ferrarini, Elisabetta Ferrero, Roberta Visone, Marco Rasponi, Marco E. Bianchi, Samuel Zambrano, Alessandra Agresti
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-18 (2024)
Abstract Multiple myeloma (MM) is linked to chronic NF-κB activity in myeloma cells, but this activity is generally considered a cell-autonomous property of the cancer cells. The precise extent of NF-κB activation and the contributions of the physi
Externí odkaz:
https://doaj.org/article/2b833cbac6f74de29ad22d2eeeb90e79
Autor:
Ian Baudi, Masanori Isogawa, Federica Moalli, Masaya Onishi, Keigo Kawashima, Yuji Ishida, Chise Tateno, Yusuke Sato, Hideyoshi Harashima, Hiroyasu Ito, Tetsuya Ishikawa, Takaji Wakita, Matteo Iannacone, Yasuhito Tanaka
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009228 (2021)
Virus infection, such as hepatitis B virus (HBV), occasionally causes endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) is counteractive machinery to ER stress, and the failure of UPR to cope with ER stress results in cell death.
Externí odkaz:
https://doaj.org/article/e016bc46b1164d8e848ca52ceee39270
Autor:
Mariana De Niz, Jessica Kehrer, Nicolas M B Brancucci, Federica Moalli, Emmanuel G Reynaud, Jens V Stein, Friedrich Frischknecht
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238134 (2020)
Malaria is a life-threatening disease, caused by Apicomplexan parasites of the Plasmodium genus. The Anopheles mosquito is necessary for the sexual replication of these parasites and for their transmission to vertebrate hosts, including humans. Imagi
Externí odkaz:
https://doaj.org/article/be9ec899051142d9b9b87742dc8b579f
Autor:
Neda Haghayegh Jahromi, Luca Marchetti, Federica Moalli, Donovan Duc, Camilla Basso, Heidi Tardent, Elisa Kaba, Urban Deutsch, Caroline Pot, Federica Sallusto, Jens V. Stein, Britta Engelhardt
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
In experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), myelin-specific T cells are activated in the periphery and differentiate in T helper (Th) 1 and Th17 effector cells, which cross the blood-brain barrier (
Externí odkaz:
https://doaj.org/article/1892b1576fe14ed993834d7fed2d5ea3
Autor:
Agata Gorecka, Souzan Salemi, Deana Haralampieva, Federica Moalli, Deborah Stroka, Daniel Candinas, Daniel Eberli, Lukas Brügger
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-12 (2018)
Abstract Background Skeletal muscle has a remarkable regenerative capacity. However, extensive damage that exceeds the self-regenerative ability of the muscle can lead to irreversible fibrosis, scarring, and significant loss of function. Adipose-deri
Externí odkaz:
https://doaj.org/article/18c7e980af8d4e369fab68abd599ace1
Autor:
Laura Megrelis, Elyas El Ghoul, Federica Moalli, Margaux Versapuech, Shamir Cassim, Nora Ruef, Jens V. Stein, Marianne Mangeney, Jérôme Delon
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
We previously identified Fam65b as an atypical inhibitor of the small G protein RhoA. Using a conditional model of a Fam65b-deficient mouse, we first show that Fam65b restricts spontaneous RhoA activation in resting T lymphocytes and regulates intran
Externí odkaz:
https://doaj.org/article/8a574cb581224a63a5b7c9b17f9d3650
Autor:
Valeria Fumagalli, Valentina Venzin, Pietro Di Lucia, Federica Moalli, Xenia Ficht, Gioia Ambrosi, Leonardo Giustini, Francesco Andreata, Marta Grillo, Diletta Magini, Micol Ravà, Christin Friedrich, Jason D. Fontenot, Philippe Bousso, Sarah A. Gilmore, Shahzada Khan, Manuel Baca, Eric Vivier, Georg Gasteiger, Mirela Kuka, Luca G. Guidotti, Matteo Iannacone
Publikováno v:
Science Immunology
Science Immunology, 2022, 7 (68), ⟨10.1126/sciimmunol.abi6112⟩
Science Immunology, 2022, 7 (68), ⟨10.1126/sciimmunol.abi6112⟩
Group 1 innate lymphoid cells (ILCs), which comprise both natural killer (NK) cells and ILC1s, are important innate effectors that can also positively and negatively influence adaptive immune responses. The latter function is generally ascribed to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5261369bdcd09e7fd92e474c3b145bf
https://doi.org/10.1126/sciimmunol.abi6112
https://doi.org/10.1126/sciimmunol.abi6112
In Vivo Function of the Lipid Raft Protein Flotillin-1 during CD8+ T Cell–Mediated Host Surveillance
Autor:
Ben J. Nichols, Nora Ruef, Nicolas Page, Guerric P. B. Samson, Verena Niggli, Jens V. Stein, Daniel F. Legler, Xenia Ficht, Federica Moalli, Doron Merkler, Alba Diz-Muñoz, Bettina Stolp
Publikováno v:
Journal of Immunology, Vol. 203, No 9 (2019) pp. 2377-2387
Flotillin-1 (Flot1) is an evolutionary conserved, ubiquitously expressed lipid raft–associated scaffolding protein. Migration of Flot1-deficient neutrophils is impaired because of a decrease in myosin II–mediated contractility. Flot1 also accumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34a0d6ad8adc5d482cde405815ae854
https://doi.org/10.4049/jimmunol.1900075
https://doi.org/10.4049/jimmunol.1900075
Autor:
Hideyoshi Harashima, Ian Baudi, Hiroyasu Ito, Federica Moalli, Matteo Iannacone, Masaya Onishi, Masanori Isogawa, Tetsuya Ishikawa, Keigo Kawashima, Yasuhito Tanaka, Takaji Wakita, Yusuke Sato
Virus infection, such as hepatitis B virus (HBV), often causes endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) is counteractive machinery to ER stress, and the failure of UPR to cope with ER stress results in cell death. Mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993753d1f79a4b35d19ea7717a4cfc82
https://doi.org/10.1101/2020.12.22.423938
https://doi.org/10.1101/2020.12.22.423938
Autor:
Federica Moalli, U. Valentin Nägerl, Christoph Schlapbach, Bettina Stolp, Philipp Germann, Oliver T. Fackler, Nicolas Page, Kirsten A. Keyser, Flavian Thelen, Lukas M. Altenburger, Matthias S. Dettmer, James Sharpe, Doron Merkler, S. Morteza Seyed Jafari, Xenia Ficht, Andrea Raimondi, Jens V. Stein, V. V. G. Krishna Inavalli, Nora Ruef, Matteo Iannacone, Francesca Barone
Publikováno v:
Science Immunology, Vol. 5, No 46 (2020) P. eaaz4371
It is well established that tissue macrophages and tissue-resident memory CD8+ T cells (TRM) play important roles for pathogen sensing and rapid protection of barrier tissues. In contrast, the mechanisms by which these two cell types cooperate for ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1038eff2b8c89f6e7956eea98a55f48f
http://doc.rero.ch/record/328393/files/ste_sgm.pdf
http://doc.rero.ch/record/328393/files/ste_sgm.pdf