Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Federica Marelli-Berg"'
Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans
Autor:
Krishnaraj S. Rathod, Vikas Kapil, Shanti Velmurugan, Rayomand S. Khambata, Umme Siddique, Saima Khan, Sven Van Eijl, Lorna C. Gee, Jascharanpreet Bansal, Kavi Pitrola, Christopher Shaw, Fulvio D’Acquisto, Romain A. Colas, Federica Marelli-Berg, Jesmond Dalli, Amrita Ahluwalia
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
Externí odkaz:
https://doaj.org/article/364a99d72c0f4fd4bf4174c52252091a
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 21 (2022)
Externí odkaz:
https://doaj.org/article/f372d55cc14b44bc92a9fc8582db8954
Autor:
Claire Vinel, Gabriel Rosser, Loredana Guglielmi, Myrianni Constantinou, Nicola Pomella, Xinyu Zhang, James R. Boot, Tania A. Jones, Thomas O. Millner, Anaelle A. Dumas, Vardhman Rakyan, Jeremy Rees, Jamie L. Thompson, Juho Vuononvirta, Suchita Nadkarni, Tedani El Assan, Natasha Aley, Yung-Yao Lin, Pentao Liu, Sven Nelander, Denise Sheer, Catherine L. R. Merry, Federica Marelli-Berg, Sebastian Brandner, Silvia Marino
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The identification of patient-specific disease mechanisms and druggable targets is crucial for precision medicine in glioblastoma. Here, the authors show that comparing patients-matched glioma-initiating cells with neural stem cells enables the disco
Externí odkaz:
https://doaj.org/article/eef727b592d24a7697303fa96e18e608
Autor:
Silvia C. Trevelin, Anna Zampetaki, Greta Sawyer, Aleksandar Ivetic, Alison C. Brewer, Lesley Ann Smyth, Federica Marelli-Berg, Robert Köchl, Robert I. Lechler, Ajay M. Shah, Giovanna Lombardi
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Nox2 is a ROS-generating enzyme, deficiency of which increases suppression by Tregs in vitro and in an in vivo model of cardiac remodeling. As Tregs have emerged as a candidate therapy in autoimmunity and transplantation, we hypothesized that Nox2 de
Externí odkaz:
https://doaj.org/article/bf2e0a61fa26400587326b11e001c154
Autor:
Kenneth Cheung, Federica Marelli-Berg
Publikováno v:
Bio-Protocol, Vol 8, Iss 12 (2018)
The vascular endothelium is essential to normal vascular homeostasis. Its dysfunction participates in various cardiovascular disorders. Murine endothelial cell culture is an important tool for cardiovascular disease research. This protocol demonstrat
Externí odkaz:
https://doaj.org/article/df72eb7f4e2f46458b950a3253d36982
Autor:
Daniel, Harding, Ming H A, Chong, Nishant, Lahoti, Carola M, Bigogno, Roshni, Prema, Saidi A, Mohiddin, Federica, Marelli-Berg
Publikováno v:
Journal of Internal Medicine. 293:23-47
Dilated cardiomyopathy (DCM) is typically defined by left ventricular dilation and systolic dysfunction in the absence of a clear precipitant. Idiopathic disease is common; up to 50% of patients with DCM have no cause found despite imaging, genetic a
Autor:
Mintu Nath, Simon P.R. Romaine, Andrea Koekemoer, Stephen Hamby, Thomas R. Webb, Christopher P. Nelson, Marcos Castellanos‐Uribe, Manolo Papakonstantinou, Stefan D. Anker, Chim C. Lang, Marco Metra, Faiez Zannad, Gerasimos Filippatos, Dirk J. van Veldhuisen, John G. Cleland, Leong L. Ng, Sean T. May, Federica Marelli‐Berg, Adriaan A. Voors, James A. Timmons, Nilesh J. Samani
Publikováno v:
European Journal of Heart Failure
European Journal of Heart Failure, 2022, ⟨10.1002/ejhf.2540⟩
European Journal of Heart Failure, 24(6), 1009-1019. Wiley
European Journal of Heart Failure, 2022, ⟨10.1002/ejhf.2540⟩
European Journal of Heart Failure, 24(6), 1009-1019. Wiley
Aims Chronic heart failure (CHF) is a systemic syndrome with a poor prognosis and a need for novel therapies. We investigated whether whole blood transcriptomic profiling can provide new mechanistic insights into cardiovascular (CV) mortality in CHF.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f876a4180b3e2e4baa65e22729feeca
https://hal.univ-lorraine.fr/hal-03671387/document
https://hal.univ-lorraine.fr/hal-03671387/document
Autor:
Jamie Chorlton, Zoe Hollowood, Carlene Dyer, Donna Lockhart, Pascal Boekman, Kieran McCafferty, Pete Coffey, Federica Marelli-Berg, John Martin
Publikováno v:
EClinicalMedicine. 51
A potential immunotherapeutic role for AZD1656 (a glucokinase activator) in the treatment of COVID-19 was hypothesized. The ARCADIA trial investigated the safety and efficacy of AZD1656 in diabetic patients admitted to hospital with COVID-19.The ARCA
Autor:
Gabriele G. Schiattarella, Pilar Alcaide, Gianluigi Condorelli, Thomas G. Gillette, Stephane Heymans, Elizabeth A. V. Jones, Marinos Kallikourdis, Andrew Lichtman, Federica Marelli-Berg, Sanjiv J. Shah, Edward B. Thorp, Joseph A. Hill
Publikováno v:
Nat Cardiovasc Res
Heart failure with preserved ejection fraction (HFpEF) is increasing in prevalence worldwide, already accounting for at least half of all heart failure (HF). As most patients with HFpEF are obese with metabolic syndrome, metabolic stress has been imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9401f22d0f459db19705fd68608af65
https://europepmc.org/articles/PMC9229992/
https://europepmc.org/articles/PMC9229992/
Autor:
Madeeha H. Sheikh, Mariella Errede, Antonio d'Amati, Noorafza Q. Khan, Silvia Fanti, Rodrigo A. Loiola, Simon McArthur, Gareth S. D. Purvis, Caroline E. O'Riordan, Davide Ferorelli, Alessandro Dell'Erba, Julius Kieswich, Chis Reutelingsperger, Eugenio Maiorano, Magdi Yaqoob, Christoph Thiemermann, Andrea Baragetti, Alberico Luigi Catapano, Giuseppe Danilo Norata, Federica Marelli‐Berg, Daniela Virgintino, Egle Solito
Publikováno v:
Faseb Journal, 36(1):e22107. FASEB
Mounting evidence has linked the metabolic disease to neurovascular disorders and cognitive decline. Using a murine model of a high-fat high-sugar diet mimicking obesity-induced type 2 diabetes mellitus (T2DM) in humans, we show that pro-inflammatory